Laboratory Technician in Pharmacology

2 weeks ago

Charlottesville, Virginia, United States Commonwealth of Virginia Full time

The Commonwealth of Virginia is seeking a Laboratory Technician or Research Associate in the field of Pharmacology, depending on the qualifications and experience of the applicant.

This role is centered around investigating clinical samples from individuals with autoimmune disorders and utilizing mouse models to explore how metal metabolism can be manipulated to enhance immune responses. The laboratory employs advanced genetic techniques, including CRISPR-Cas9 screening, to pinpoint metabolic genes that are vital for the survival and functionality of immune cells, particularly T cells, as they engage with healthy tissues.

The primary objective is to leverage these foundational insights to develop targeted therapies that promote anti-inflammatory responses in patients afflicted with autoimmune conditions such as Systemic lupus erythematosus (SLE), Type 1 diabetes (T1D), and Inflammatory bowel disease (IBD) and colitis.

A unique aspect of this laboratory's research is its focus on the metabolism of iron within immune cells, recognizing the critical role of iron in bodily functions while also addressing the risks associated with its excess, which can lead to ferroptosis. Investigating how variations in iron metabolism, such as those seen in iron deficiency anemia or iron overload disorders, influence immune system behavior is a significant area of study.

This position offers an excellent opportunity for recent graduates seeking to gain research experience prior to pursuing advanced degrees such as PhD, MD, or MD-PhD programs. Individuals in these roles will have the chance to contribute to research publications, thereby enhancing their professional development.

Key Responsibilities:Processing and managing patient blood samples for research purposes.Maintaining accurate laboratory records through both digital and traditional methods.Presenting research outcomes during laboratory meetings.Conducting various experiments, including immune cell isolation, cell culture, flow cytometry, western blotting, RNA sequencing, and viral particle generation.Overseeing laboratory supplies, managing purchases, and ensuring the laboratory environment is well-maintained.Performing other assigned tasks as needed.Minimum Qualifications:Laboratory Technician 1Education: High school diploma or equivalent.Experience: At least 1 year of laboratory experience, including student involvement. A Bachelor's degree may substitute for experience.Laboratory Technician 2Education: Associate's degree.Experience: Minimum of 2 years of laboratory experience, including student involvement. A Bachelor's degree in a relevant field may substitute for experience.Laboratory SpecialistEducation: Bachelor's degree.Experience: 3 years of relevant experience. 6 years of laboratory-related experience may substitute for a degree.Preferred Qualifications:Prior laboratory experience with fundamental molecular biology techniques, flow cytometry, and western blotting.Familiarity with handling laboratory animals is preferred.Proficiency in software applications such as Microsoft Word, PowerPoint, and Excel.Able to work independently as well as collaboratively in a supportive team environment.Strong communication and organizational skills.Physical Requirements:This position may require extended periods of standing, squatting, keyboarding, and performing delicate experiments and animal care.

The availability of this position is contingent upon project requirements, funding, and performance evaluations. For more information regarding benefits, please refer to the official resources. Applications will be reviewed until the position is filled. Background checks are mandatory for all new hires, and a pre-employment health assessment is required.

Application Process:

Interested candidates should apply through the designated application portal, ensuring that all necessary documents, including a CV or resume and a cover letter, are submitted. Incomplete applications may not be fully considered.

References will be requested through the standardized process. For any inquiries related to the application, please reach out to the designated recruiting specialist.

The Commonwealth of Virginia is committed to fostering diversity among its faculty and staff, adhering to equal opportunity and affirmative action policies to ensure fair consideration for all qualified candidates.

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