Laboratory Technician

1 week ago

Charlottesville, Virginia, United States Commonwealth of Virginia Full time

The Commonwealth of Virginia is seeking a Laboratory Technician or a Research Lab Specialist within the field of pharmacology, contingent upon the qualifications and experience of the selected candidate.

This laboratory is dedicated to investigating clinical samples from individuals with autoimmune disorders and utilizing mouse models to explore how metal metabolism can be manipulated to enhance immune responses. By employing unbiased genetic CRISPR-Cas9 screening techniques in immune cells, such as T cells, the laboratory identifies metabolic genes that are vital for their survival and functionality during immune attacks on healthy tissues. The overarching goal is to leverage these foundational insights to develop targeted therapies that favor anti-inflammatory cells over inflammatory ones in patients afflicted with autoimmune conditions.

A distinctive focus of this laboratory's research is the metabolism of iron within immune cells, given the critical role of iron in physiological processes and the potential hazards associated with its excess, which can lead to ferroptosis. Investigating how variations in iron metabolism, including conditions like iron deficiency anemia or iron overload disorders, may influence immune system functionality is a significant area of research.

This position presents an excellent opportunity for recent graduates seeking research experience prior to pursuing advanced degrees such as PhD, MD, or MD-PhD programs. Technicians and specialists in this laboratory will have the opportunity to contribute to scholarly manuscripts, thereby gaining invaluable experience.

Key Responsibilities:Processing patient blood samples for research purposes.Maintaining accurate laboratory records through both digital and traditional methods.Presenting research outcomes during laboratory meetings.Conducting experiments, including immune cell isolation, cell culture, flow cytometry, western blotting, RNA sequencing, and viral particle generation.Overseeing laboratory supplies, managing purchases, and ensuring overall lab maintenance.Performing other assigned tasks as required.Minimum Qualifications:Laboratory Technician 1Education: High school diploma or equivalent.Experience: Minimum of 1 year of laboratory experience, including student involvement. A Bachelor's degree may substitute for experience.Laboratory Technician 2Education: Associate's degree.Experience: At least 2 years of laboratory experience, including student involvement. A Bachelor's degree in a relevant field may substitute for experience.Research Lab SpecialistEducation: Bachelor's degree.Experience: 3 years of relevant experience. 6 years of laboratory-related experience may substitute for a degree.Preferred Qualifications:Prior laboratory experience with fundamental molecular biology techniques, flow cytometry, and western blotting.Familiarity with mouse handling is advantageous.Proficiency in software applications such as Microsoft Word, PowerPoint, and Excel.Able to work independently as well as collaboratively in a supportive team environment.Strong communication and organizational skills.Physical Requirements:This role may require extended periods of standing, squatting, keyboarding, and conducting delicate experiments and animal care.

The availability of this position is contingent upon project requirements, funding, and performance evaluations. For more information regarding benefits, please refer to the official resources. Applications will be reviewed until the position is filled. Background checks are mandatory for all new hires, and a pre-employment health assessment is required.

Application Process:

Interested candidates should apply through the designated application portal, ensuring that their submission includes a CV or Resume along with a Cover Letter. Incomplete applications will not be fully considered.

References will be requested through the standardized process. For any application-related inquiries, please reach out to the designated recruiting specialist.

The Commonwealth of Virginia is committed to fostering diversity among its faculty and staff. Equal opportunity and affirmative action policies are in place to ensure fair consideration for all qualified applicants.

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