Senior Scientist I, Biologics Drug Product Development

1 month ago


South San Francisco, California, United States AbbVie Full time

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us Follow @abbvie onTwitter,Facebook,Instagram,YouTubeandLinkedIn.
Job Description

The Biologics Drug Product Development group within AbbVie is a global organization responsible for developing and characterizing drug product formulations and manufacturing processes for biologic therapeutics (antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats) from preclinical development through clinical proof of concept.

We have an exciting opportunity for a Senior Scientist I to join our team at our Bay Area site in South San Francisco, CA.

KEY RESPONSIBILITIES INCLUDE:

Develop stable and fit-for-purpose liquid and lyophilized drug products through the design and execution of formulation, process development, and clinical in-use studies.Support testing of representative stability lots to support drug substance and drug product shelf-life extension.Generate high-quality data based on sound scientific principles and document results in electronic lab notebook.Prepare scientific presentations, technical reports, and regulatory documents.Drive innovation and continuously enhance capabilities and business processes within the organization.Work efficiently and collaboratively in an agile team setting with minimal direction from supervisors.Represent the function within cross-functional and cross-site technical teams.
Qualifications
Ph.D. in chemical engineering, pharmaceutical sciences, material science, analytical sciences or equivalent field with 0-3 years of experience or BS/MS degree with 8-10 years of relevant experience in the biotechnology or pharmaceutical industry.Strong technical background in protein formulation principles, drug product degradation pathways, drug product lyophilization, and characterization approaches.Hands-on experience in analytical techniques used for protein characterization and stability testing preferred (e.g., SEC, CE-SDS, icIEF, HIAC, MFI, DLS, etc.).Technical experience with developing fit-for-purpose analytical characterization techniques is desired.Prior experience in the development of protein product formulations is highly desirable.Detail-oriented and highly organized with a demonstrated ability to drive innovative science and solve complex problems.Excellent communication and written skills
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees. This job is eligible to participate in our short-term incentive programs. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent with applicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status. US & Puerto Rico only - to learn more, visit

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