Assistant Scientist in Translational Research

2 weeks ago


South San Francisco, California, United States TalentBurst Full time

Position: Bioconjugation Research Scientist - I (Assistant)

Location:
South SF, CA

Duration: 12+ months

Overview:

This role is focused on bioconjugation within the Discovery Chemistry group.

We are seeking a highly motivated and exceptional individual to join our Discovery Chemistry Department.


The successful candidate will collaborate with multidisciplinary teams to develop innovative medicinal solutions by utilizing optimized conjugation protocols, analytical methodologies, and data interpretation to create drug candidates and intermediates.Strong interpersonal, teamwork, and communication skills are essential for success in this collaborative environment.Additionally, the candidate is expected to quickly adapt through hands-on training to enhance their skills and independence in reaction setup, route design, and optimization.
Key Responsibilities:

Conduct bioconjugation of linker-payload combinations to antibodies, focusing on established in-house methods.Select and implement suitable purification techniques for biologics, including SEC, hydrophobic interaction chromatography, and ion exchange chromatography.Gather and analyze analytical data, such as LC/MS results.Qualifications

This position requires a focus on bioconjugation, so please ensure that applications reflect this specialization.


Educational Background:

A minimum of a B.S./M.S./Ph.D. in chemistry, biochemistry, or a related discipline, along with relevant industrial or academic experience.
Required Experience and Skills:

Practical experience in the conjugation, purification, and characterization of antibody-drug conjugates, along with proficiency in analytical techniques and instrumentation, including chromatographic methods such as HIC, RP, SEC, SDS-PAGE, and UV-Vis.
Preferred Skills:
Experience in biologics analytics and purification techniques.

Essential Qualifications:
Experience in bioconjugation, with a strong foundation in protein biochemistry and chemistry.

Personal Attributes:
A collaborative team player who adheres to timelines and communicates effectively.

Note:
This is an onsite, lab-based role with potential for extension.

#TB_PH


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