Bioconjugation Research Scientist
2 weeks ago
Position: Bioconjugation Research Scientist
Company: Net2Source Inc.
Duration: 12 Months
Key Responsibilities:
This role focuses on the bioconjugation processes within the Discovery Chemistry division. The ideal candidate will be an innovative and driven scientist eager to contribute to the development of novel therapeutic agents.
The selected individual will collaborate with diverse teams to create Client pharmaceuticals by utilizing refined conjugation methodologies, analytical evaluations, and data interpretation to develop drug candidates and their intermediates. Strong interpersonal, teamwork, and communication skills are essential for success in this collaborative environment. The candidate is expected to rapidly acquire skills through practical training, becoming proficient and autonomous in reaction setup, route design, and optimization.
Core Duties Include:
• Conduct bioconjugation of linker-payload combinations to antibodies, focusing on established internal methodologies.
• Choose and implement suitable purification methods for biologics, including SEC, hydrophobic interaction chromatography, and ion exchange chromatography.
• Gather and analyze analytical data, such as LC/MS results.
Qualifications:
Educational Background:
• A minimum of a B.S., M.S., or Ph.D. in chemistry, biochemistry, or a related discipline, complemented by relevant industrial or academic experience.
Experience and Skills:
• Practical experience in the conjugation, purification, and characterization of antibody-drug conjugates, along with proficiency in analytical techniques and instrumentation, including chromatographic methods such as HIC and RP, SEC, SDS-PAGE, and UV-Vis.
• Preferred skills: Experience in biologics analytics and purification techniques.
• Essential skills: Expertise in bioconjugation, protein biochemistry, and a solid chemistry foundation.
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