Principal Immunologist, Preclinical Research

6 days ago


Cambridge, Massachusetts, United States Flagship Ventures Full time
Job Summary

We are seeking a highly skilled PhD-level Principal Scientist with expertise in immunology and preclinical research to join our team at Flagship Ventures.

Key Responsibilities
  • Lead and manage immunology and preclinical research projects, ensuring scientific rigor and excellence.
  • Develop and validate immunological assays (e.g., flow cytometry, ELISA, CyTOF, cytokine profiling) to evaluate drug candidates' efficacy and mechanism of action.
  • Oversee in vivo and in vitro studies, including development and optimization of disease models, study design, data collection, and interpretation.
  • Collaborate closely with cross-functional teams (molecular biology, bioinformatics, clinical development) to achieve integrated research objectives.
  • Stay abreast of advancements in immunology and adopt new technologies and methodologies that enhance our research capabilities.
  • Prepare and review scientific publications, presentations, and regulatory documents.
  • Mentor and develop scientists and research associates, fostering a culture of scientific excellence.
  • Present research findings to internal and external stakeholders, including at conferences and to regulatory bodies.
Qualifications
  • PhD in Immunology, Cell Biology, Molecular Biology, or a related discipline.
  • 12+ years of relevant post-Ph.D. experience in immunology and preclinical research, with at least 3+ years in a leadership role in industry.
  • Extensive expertise in immunological techniques and assays.
  • Strong background in developing and executing preclinical models and studies.
  • Proven success in project management and team leadership.
  • Previous management experience/developing employees.
  • Excellent communication and presentation skills.
  • Proficiency in data analysis and scientific software.
  • Familiarity with regulatory guidelines and requirements for preclinical research.
Preferred Qualifications
  • Experience in the biopharmaceutical industry.
  • Knowledge in autoimmune diseases, oncology, or infectious diseases.
  • Experience in bioinformatics and computational biology tools.


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