In Vitro Pharmacologist, Obesity Research

2 months ago


Cambridge, Massachusetts, United States Eli Lilly and Company Full time

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company, focuses on the discovery of biologic, small molecule, and genetic therapeutics for the treatment of diabetes, obesity, and associated complications. We are seeking a skilled, motivated, and versatile individual who can help to build a highly collaborative, successful drug discovery and development team in the Obesity research group in Boston. The successful candidate will use a strong background in cell culture and cell-based functional assays to play a critical role in supporting end-to-end discovery efforts and established pipeline projects with an emphasis on anti-obesity therapeutics. The candidate would support assay development and conduct established assays to validate new targets and characterize the in vitro function of novel therapeutics. The candidate will be responsible for setting up critical capabilities in the laboratory setting and working with other scientists within and across departments to achieve project and department goals.

Interested in engaging with groundbreaking science? Apply now to become a part of the Lilly TeamKey position requirements/responsibilities include:

Technical/scientific skills. Expertise in the following is a must-have:

Aseptic cell culture techniques with mammalian cells, transient transfections and generation of stable cell lines.Gene expression studies by qPCR, western blot and FACS techniques.Development of functional cell-based functional assays and screening of novel therapeutics in 96-/384-well plate formats.Knowledge of basic pharmacology (e.g. determination of binding affinity, potency and in vitro efficacy).Experience with colorimetric, luminescence and fluorescence-based readouts.Proficient in operating liquid handling robots and automating assaysSoft skills:Proficient oral and written communication skills and ability to work both independently and in teams.Requirement for accurate record keeping and independent data analysis. Will perform work in full compliance with Lilly Research Policies and complete all required training activities in the timeframe specified.Attention to detail and ability to prioritize work on multiple projects, timelines and company goals.Eager to grasp fundamental principles, swiftly acquire new abilities, and adjust to novel challenges.Minimum qualifications:B.S. and/or M.S. in Biology, Pharmacology, Biochemistry or related field5+ years of laboratory experienceAdditional Skills/Preferences Experience/expertise with the following is a plus: Working with native cell lines and primary cultures.Exposure to multiple therapeutic target classes and modalities.Working knowledge or background in cardiometabolic diseases Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups. #WeAreLilly

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