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Associate Scientist II

3 months ago

Massachusetts, United States AbbVie Full time

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Job Description

Key Responsibilities

Responsible for working with various separation/detection platforms (PA800+, GXII-Touch, Maurice, iCE3, & UPLC/HPLC with UV, fluorescence, CAD or MS detection) & robotic liquid handlers (Protein Maker, Hamilton Star, and Tecan).Support early & late-stage CMC development activities including cell line development (CLD), cell culture development (CCD), & purification development for product quantitation, product quality & process impurities for biologic molecules.Develop & implement small-scale protein purification workflows by employing experience in protein purification techniques such as FPLC, IEX, SEC, HIC, etc.Develop & implement high-throughput & automated chromatography (HPLC/UPLC, etc.), capillary electrophoresis (icIEF, CE-SDS, etc.) & spectroscopy (UV-Vis, etc.) based analytical methods for protein characterization.Organize & document experiments & results in electronic lab notebook (ELN) and lab informatics management system (LIMS).Author technical memos & technical reports.Employ experience in chromatography data software (ChemStation, Empower, etc.) and electronic notebook software (IDBS ELN, etc.).Provide analytical support for process development, process characterization, PPQ, and GMP campaign for biologic entities.Responsible for utilizing different separation techniques such as icIEF, SEC, CEX & Poros A.Serve as Separation Lead for pipeline biologics programs.Responsible for data interpretation & trending to enable data-driven decision making with other functional teams (CC,CLD, Purification, & Pilot Lab).Improve operational workflows & data management workflows.
Qualifications
Must possess a Bachelors degree or foreign academic equivalent in Analytical Chemistry, Biochemistry, Biotechnology or a highly related field of study with at least 2 years of related experience. In the alternative, will accept a Masters degree or foreign academic equivalent in Analytical Chemistry, Biochemistry, Biotechnology or a highly related field of study with academic or industrial background in related field. Each alternative with academic or industrial background in:
  1. developing & implementing small-scale protein purification workflows by employing experience in protein purification techniques such as FPLC, IEX, SEC, HIC, etc;
  2. developing & implementing high-throughput and automated chromatography (HPLC/UPLC, etc.), capillary electrophoresis (icIEF, CE-SDS, etc.) & spectroscopy (UV-Vis, etc.) based analytical methods for protein characterization;
  3. chromatography data software (ChemStation, Empower, etc.) & electronic notebook software (IDBS ELN, etc.); &
  4. providing analytical support for process development, process characterization, PPQ, & GMP campaign for biologic entities. Employer will accept any suitable combination of education, training or experience related to the job opportunity. Apply online at Refer to Req ID: REF23448X.


    Additional Information

    We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term and long-term incentive programs.

    AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.