Current jobs related to Senior Scientist I - Massachusetts - AbbVie


  • Watertown, Massachusetts, United States VHB Full time

    Job Title: Senior Environmental ScientistWe are seeking a highly skilled Senior Environmental Scientist to join our team at VHB. As a Senior Environmental Scientist, you will play a key role in supporting current and future projects, working in the field and office, and providing excellent growth opportunities within a vibrant team of...


  • Cambridge, Massachusetts, United States AbbVie Full time

    About the RoleWe are seeking a highly motivated and experienced Senior Scientist to join our Molecular Profiling and Drug Delivery (MPDD) team at AbbVie. As a Senior Scientist, you will play a key role in leading CMC developability assessment for emerging molecules on small molecule pipeline programs.Key ResponsibilitiesLead CMC developability assessment for...


  • Waltham, Massachusetts, United States AbbVie Full time

    Job SummaryWe are seeking a highly skilled Senior Process Development Scientist to join our team at AbbVie. As a key member of our process development group, you will be responsible for driving late-stage process development activities of novel antibody-drug conjugates (ADCs).Key ResponsibilitiesIndependently design, execute, and interpret critical...

  • Senior Scientist, II

    2 weeks ago


    Cambridge, Massachusetts, United States AbbVie Full time

    Job Overview AbbVie's Molecular Profiling and Drug Delivery (MPDD) organization is seeking a highly motivated and talented scientist to serve as a Senior Scientist II. The primary role of this position is to lead CMC developability assessment for emerging molecules on small molecule pipeline programs. The successful candidate will work collaboratively with...


  • Cambridge, Massachusetts, United States Bicycle Therapeutics Full time

    Job DescriptionWe are seeking a highly skilled Senior Translational Data Scientist to join our Translational Sciences team at Bicycle Therapeutics. This individual will be responsible for leading the development, customization, and maintenance of a biomarker software solution to support our clinical-stage oncology portfolio assets.Key Responsibilities:Lead...


  • Worcester, Massachusetts, United States University of Massachusetts Medical School Full time

    Job Summary:The University of Massachusetts Medical School seeks a highly skilled and experienced Senior Research Scientist to join our team. As a key member of our research laboratory, you will be responsible for designing and implementing complex research experiments, analyzing data, and presenting research results.Key Responsibilities:Design and implement...


  • Massachusetts, United States HireMinds Full time

    Job SummaryHireMinds is seeking a highly skilled Senior Scientist to join our team in the field of Next-Generation Sequencing (NGS). As a key member of our team, you will be responsible for developing and optimizing NGS assays, staying up-to-date with the latest advancements in the field, and collaborating with computational experts to turn data into...


  • Boston, Massachusetts, United States Two95 International Inc. Full time

    Job Title: Sr. Software Engineer/Data ScienceAbout the Role:We are seeking a highly skilled and experienced Senior Software Engineer/Scientist to join our team at Two95 International Inc. as a Lead Data Science Professional. The successful candidate will be responsible for leading the development of data-driven solutions and driving business growth through...


  • Massachusetts, United States Partners HealthCare Full time

    Comprehensive Benefits Package, Immediate Health Coverage, $10,000 Signing Bonus Role Overview: Testing Personnel as defined by CLIA The Clinical Laboratory Scientist, serving as Testing Personnel under CLIA guidelines, is responsible for conducting both waived and non-waived laboratory tests. Each professional is authorized to perform only those tests...


  • Massachusetts, United States Partners HealthCare Full time

    Exciting Opportunity with Comprehensive Benefits Position Overview: The Clinical Laboratory Scientist plays a crucial role in the healthcare system, functioning as Testing Personnel as per CLIA regulations. This position involves performing both waived and non-waived laboratory tests. Each professional is responsible for conducting tests that have been...


  • Boston, Massachusetts, United States The Vertex Companies, LLC Full time

    Job OverviewThe Vertex Companies, LLC is on the lookout for a Senior Environmental Engineer/Scientist to spearhead the development and execution of comprehensive assessment and remediation initiatives across New England. Our clientele encompasses a wide range of stakeholders, including private developers, property owners, legal representatives, and various...


  • Cambridge, Massachusetts, United States AbbVie Full time

    Job SummaryWe are seeking a highly motivated and experienced analytical scientist to lead a team of analytical scientists supporting early phase development of New Chemical Entities (NCEs) drug substance and drug product in both preclinical and clinical. The ideal candidate will have extensive expertise in applying regulatory guidelines within an R&D...


  • Massachusetts, United States HireMinds Full time

    Job SummaryHireMinds is seeking a highly skilled Senior Scientist to join our team in the field of Next-Generation Sequencing (NGS). As a key member of our team, you will be responsible for developing and optimizing NGS assays, staying up-to-date with the latest advancements in the field, and collaborating with computational experts to turn data into...


  • Cambridge, Massachusetts, United States Bicycle Therapeutics Full time

    Job SummaryBicycle Therapeutics is seeking a highly motivated and experienced Clinical Scientist (Associate Director) to provide scientific support for all clinical development activities involving the conduct of clinical studies. This role will sit within the clinical department, working to advance Bicycle Toxin Conjugates and Bicycle Immune Agonists as...


  • Cambridge, Massachusetts, United States Foghorn Therapeutics Full time

    About the RoleFoghorn Therapeutics is seeking a highly skilled and experienced Senior Analytical Development Scientist to join our team. As a key member of our Analytical Development and Quality Control department, you will be responsible for driving the analytical development and QC functions, ensuring the successful advancement of small molecule candidates...


  • Waltham, Massachusetts, United States AbbVie Full time

    Job Summary:AbbVie is seeking a highly skilled Senior Research Scientist to join our Process Development team. As a key member of our team, you will be responsible for driving late-stage process development activities of novel antibody-drug conjugates (ADCs).Key Responsibilities:Independently design, execute, and interpret critical experiments to answer...


  • Framingham, Massachusetts, United States Replimune, Inc. Full time

    Job Summary:We are seeking a highly skilled Senior Scientist, Process Development and Optimization to join our team at Replimune, Inc. in Framingham. As a key member of our Process Development team, you will be responsible for leading drug substance process development lab-based process characterization and optimization activities and personnel in support of...


  • Cambridge, Massachusetts, United States Editas Medicine Full time

    About Editas MedicineEditas Medicine is a pioneering biotechnology company dedicated to harnessing the power of genetic innovation to transform healthcare. Our mission is to redefine the treatment of serious diseases by leveraging cutting-edge gene editing technologies.Job SummaryWe are seeking a highly skilled Senior Scientist, Molecular Bioanalytics to...


  • Cambridge, Massachusetts, United States AbbVie Full time

    Drug Product Design and Development is a critical function at AbbVie, responsible for creating formulations that enable the delivery of our candidate molecules in a dosage form intended for commercialization. We are seeking a highly motivated and collaborative Senior Scientist to join our team in Cambridge, MA.Key responsibilities include:* Leading the...


  • Cambridge, Massachusetts, United States Editas Medicine Full time

    Transformative Therapies at Editas MedicineWe're driven by a collective purpose to bring life-changing therapies to people living with serious diseases. Our scientific innovation fuels our drive to excel, harnessing the power of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing.Our CultureWe believe our people are at the core of everything we do. We're...

Senior Scientist I

4 months ago


Massachusetts, United States AbbVie Full time

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Job Description

Key Responsibilities

Responsible for developing, optimizing & executing new analytical methods & techniques to characterize complex proteins/glycoproteins, antigens & novel protein-based therapeutics.Work within multi-disciplinary project teams & act as a lead analytical & biophysical resource to guide development & advance pipeline.Resolve key project challenges by effectively utilizing available analytical tools, information & technical expertise.Develop, optimize & execute new analytical methods & techniques to characterize complex proteins/glycoproteins, antigens & novel protein-based therapeutics.Strategically advance scientific expertise within the Analytics group by conceiving & executing novel scientific research & development efforts to address project challenges & provide novel insights.Demonstrate leadership by advising & sharing knowledge & expert opinions with peers & senior management.Contribute to research that leads to peer-reviewed publications, reports & external presentations.Employ experience in protein analytical & biophysical characterization to discern protein critical quality attributes (physiochemical properties, post-translational modifications) & better understand protein structure-function relationships.Work in cross-functional teams with scientists across functions & therapeutic areas (Virology, Immunology, Oncology & Neuroscience) to discover & develop next generation biologics through interrogation & engineering of protein attributes across both targets and therapeutic molecules.Responsible for utilizing verbal & written skills & the ability to clearly present scientific concepts & results for functional scientific & non-scientific leaders.Employ experience with in-depth protein analytical characterization using a variety of techniques such as LC-MS/MS, SE-HPLC, CE, CD, NMR, TEM, SE-HPLC-MALS, DLS, iCIEF.Employ experience utilizing various software such as Thermo Xcalibur, BSI PEAKS, PMI Byologic, Wyatt Astra, Wyatt Dynamics, MS Word, MS Excel, MS Ppt, PRISM, & ImageJ.Responsible for demonstrating proficiency with various chromatographic techniques, capillary electrophoresis methodologies & in-depth biophysical characterization.Responsible for preparation and characterization of disease-relevant proteins in defined morphological states. Employ experience in guiding recombinant protein expression & purification.Employ experience with protein labeling & conjugation, as well as protein formulation & remediation. Prepare written documentation, reports & presentations of work & strategies.Work on the selection of targets or variants for therapeutic development & include the design, engineering & characterization of resulting therapeutics & their mechanisms of action.Employ experience with routine mass spectrometry workflows, including intact & subunit analysis.Responsible for project driven initiatives that will require scientific exploration & experimentation as well as close collaboration with scientists across the organization.Responsible for new technology development by expanding analytical expertise & custom assays, project leadership, hypothesis-driven experimentation, orientated towards discovering & developing novel therapeutics.
Qualifications
Must possess a Bachelors or foreign equivalent degree in Chemistry, Chemical Biology, Chemical Engineering, Biochemistry, Biophysics, or a highly related field of study plus 10 years of related progressive experience. In the alternative, employer will accept a Masters degree or foreign equivalent in Chemistry, Chemical Biology, Chemical Engineering, Biochemistry, Biophysics, or a highly related field of study plus 8 years of related progressive experience, or employer will accept a Ph.D. degree or foreign equivalent in Chemistry, Chemical Biology, Chemical Engineering, Biochemistry, Biophysics, or a highly related field of study plus an academic or industrial background. Must possess expertise/knowledge sufficient to adequately perform the duties of the job being offered. Expertise/knowledge may be gained through employment experience or education. Such expertise/knowledge cannot be quantified by time. Required expertise/knowledge includes: (i) developing, optimizing and executing new analytical methods and techniques to characterize complex proteins/glycoproteins, antigens and novel protein-based therapeutics; (ii) in-depth protein analytical characterization using a variety of techniques including: LCMS/MS, SE-HPLC, CE, CD, NMR, TEM, SE-HPLC-MALS, DLS, iCIEF; (iii) software such as Thermo Xcalibur, BSI PEAKS, PMI Byologic, Wyatt Astra, Wyatt Dynamics, MS Word, MS Excel, MS Ppt, PRISM, & ImageJ; (iv) various chromatographic techniques, capillary electrophoresis methodologies and in-depth biophysical characterization; (v) routine mass spectrometry workflows, including intact and subunit analysis; & (vi) expanding analytical expertise and custom assays, project leadership, hypothesis-driven experimentation, orientated towards discovering & developing novel therapeutics. Employer will accept any suitable combination of education, training or experience. Apply online at Refer to Req ID: REF24400D.


Additional Information

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term and long-term incentive programs.

AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVies policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.