Soluble Biomarker Laboratory, Clinical Assay Development- Principal Scientist
5 days ago
HOW MIGHT YOU DEFY IMAGINATION?
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Principal Scientist-Soluble Biomarker Laboratory, Clinical Assay Development
What you will doLet’s do this. Let’s change the world. In this vital role you as an integral member of a dynamic group of scientists and platform experts will perform and evaluate clinical biomarker assays employing a variety of platforms to support our drug development efforts.
Responsibilities include but are not limited to:- Employ a wide variety of platforms in our biomarker laboratory to develop and qualify biomarker assays to support various clinical programs and assess soluble biomarkers.
- Choose the most appropriate platform to address biomarker questions by employing innovative approaches.
- Collaborate with scientists representing multiple therapeutic areas and work closely with groups in other functional areas.
- Analyze, interpret, and present data to the partners.
- Work collaboratively with internal and external partners and manage vendors.
We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a scientist with these qualifications.
Basic Qualifications:- Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 2 years of scientific/technical experience OR Master’s degree and 5 years of scientific/technical experience OR Bachelor’s degree and 7 years of scientific/technical experience.
- Deep understanding of biomarker assay platforms particularly those that are used to assess soluble biomarkers such as ELISA, Luminex, MSD, Simple Plex, and Simoa is required; Firm understanding of quantitative LC/MS and proteomics platforms such as O-Link and SomaLogic is preferred; knowledge of cell-based (including flow cytometry and immunohistochemistry) and genomics platforms is a plus.
- Basic understanding of disease biology and biomarker approaches in multiple therapeutic areas.
- Experience working and coordinating with internal stakeholders and team members as well as external partners such as CROs and vendors to support outsourced activities.
- Basic knowledge of working in a regulated environment; Review and draft requirements documents (SOPs, guidelines and work instructions).
- Familiarity with processes and factors needed to evaluate, qualify, and manage CROs.
- Experience working in a matrixed environment to implement biomarker assay development and validation employing innovative approaches to support clinical trials.
- Project management skills to meet critical timelines associated with various activities necessary to support biomarker assessment of clinical samples.
- Demonstrated track record of critical independent thinking, troubleshooting ability and innovative approaches to solve complex questions is highly desirable.
- Ability to multi-task and manage multiple studies, strong verbal and written communication skills with a high degree of motivation, creativity and collaborative qualities.
- Experience with complex data analysis and interpretation.
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
- Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
- Stock-based long-term incentives.
- Award-winning time-off plans and bi-annual company-wide shutdowns.
- Flexible work models, including remote work arrangements, where possible.
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
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