Principal Scientist

4 days ago


San Francisco, California, United States Amgen Full time
About the Role

We are seeking a highly skilled and experienced Principal Scientist to join our Soluble Biomarker Laboratory, Clinical Assay Development team at Amgen. As a key member of our team, you will be responsible for developing and evaluating clinical biomarker assays employing a variety of platforms to support our drug development efforts.

Key Responsibilities
  • Develop and qualify biomarker assays to support various clinical programs and assess soluble biomarkers.
  • Choose the most appropriate platform to address biomarker questions by employing innovative approaches.
  • Collaborate with scientists representing multiple therapeutic areas and work closely with groups in other functional areas.
  • Analyze, interpret, and present data to partners.
  • Work collaboratively with internal and external partners and manage vendors.
Requirements
  • Doctorate degree (PhD, PharmD, or MD) with 2 years of scientific/technical experience, or Master's degree with 5 years of experience, or Bachelor's degree with 7 years of experience.
  • Deep understanding of biomarker assay platforms, particularly those used to assess soluble biomarkers.
  • Firm understanding of quantitative LC/MS and proteomics platforms.
  • Basic understanding of disease biology and biomarker approaches in multiple therapeutic areas.
  • Experience working and coordinating with internal stakeholders and team members, as well as external partners.
  • Basic knowledge of working in a regulated environment.
  • Familiarity with processes and factors needed to evaluate, qualify, and manage CROs.
  • Project management skills to meet critical timelines associated with various activities necessary to support biomarker assessment of clinical samples.
  • Demonstrated track record of critical independent thinking, troubleshooting ability, and innovative approaches to solve complex questions.
  • Ability to multi-task and manage multiple studies, strong verbal and written communication skills, with a high degree of motivation, creativity, and collaborative qualities.
  • Experience with complex data analysis and interpretation.
About Amgen

At Amgen, our shared mission is to serve patients by developing innovative treatments that take care of others. We are committed to providing a work environment that supports the growth and well-being of our teammates. As a valued member of our team, you will have access to a comprehensive benefits package, including health and welfare plans, financial plans, work/life balance, and career development opportunities.

We are an Equal Opportunity employer and welcome applications from diverse candidates. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.


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