Scientist - In Vivo Pharmacology (Inflammation Research)

1 month ago


South San Francisco, California, United States Amgen Full time

HOW MIGHT YOU DEFY IMAGINATION?

You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world's leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Scientist - In Vivo Pharmacology (Inflammation Research)

Live

What you will do

Let's do this. Let's change the world. The Department of Inflammation Research is seeking a dedicated, driven and independent Scientist to join the In Vivo Pharmacology (IVP) group as part of a fast-paced, integrated and interactive research group exploring therapeutics for Inflammation, Autoimmune, and Rare Disease programs. In this vital role you will be responsible for designing and executing experiments exploring and understanding the pharmacology of drug targets; generating, communicating pharmacology and preclinical data to support the progression of research projects, and providing technical expertise to therapeutic area scientists.

Key Responsibilities:

  • In lab in vivo bench work
  • Design, execute, analyze and report in vivo and in vitro study results to project collaborators and teams.
  • Collaborate with in vivo pharmacology (IVP), therapeutic area (TA) scientists, and subject matter experts to ensure efficient in vivo pharmacology support.
  • Utilize in vivo pharmacology and animal models to validate and accelerate molecules through the research pipeline.
  • Present results at internal meetings and external conferences.
  • Publish experimental findings.

Win

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a driven, pro-active, independent, and enthusiastic scientist who wants to contribute to groundbreaking science and serve patients in a highly productive team environment with these qualifications.

Basic Qualifications:

Doctorate degree in Immunology or related disciplines

Or

Master's degree and 2 years of Immunology or related experience

Or

Bachelor's degree and 4 years of Immunology or related experience

Preferred Qualifications:

  • PhD degree in Immunology or related disciplines, or BS/MS degree with commensurate scientific / drug discovery experience and track record of scientific excellence and productivity.
  • Willingness and curiosity to learn and explore new areas of research
  • Experience designing and executing in vivo preclinical inflammation and autoimmune disease models. Experience with colitis (DSS, CD45RBhi T cell transfer, IL-10 KO), lupus (NZB/W, MRL-lpr, Imiquimod), and arthritis (CIA, CAIA) models preferred.
  • Hands-on experience in cellular, biochemical, histological, and molecular biology assay techniques (i.e. ELISA, MSD, multi-color flow cytometry, quantitative RT-PCR) preferred.
  • Computer literacy, especially proficiency with GraphPad Prism, Excel, PowerPoint and Word.
  • Attention to detail, excellent organizational and communication skills, accurate & timely record keeping and data analysis are essential.
  • Demonstrated track record of independent critical thinking and scientific achievement.
  • Demonstrated experience in pharmacology and in vivo models of inflammation/Immunology.
  • Ability to work in a flexible team-oriented environment

Thrive

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates' professional and personal growth and well-being.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.




  • South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...


  • San Francisco, California, United States city of San Elizario Full time

    About the RoleWe are seeking a highly skilled and experienced Senior Scientist to join our Inflammation Research team in San Elizario. As a key member of our team, you will be responsible for designing and executing experiments to explore and understand the pharmacology of drug targets, generating and communicating pharmacology and preclinical data to...

  • Sr. Scientist

    1 month ago


    South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products...


  • San Diego, California, United States Lundbeck Full time

    Are you ready to be part of a team where your contributions matter, the challenges are intricate, and you can witness the impact of your efforts? At Lundbeck, our unwavering commitment is to restore brain health, enabling every individual to reach their full potential. As a unique global biopharmaceutical entity, we focus exclusively on brain diseases. The...

  • Sr. Scientist

    1 month ago


    South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?If you feel like you're part of something bigger, it's because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world's leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better...


  • San Diego, California, United States Lundbeck Full time

    Join Our Mission: At Lundbeck, we are passionately committed to enhancing brain health, enabling individuals to reach their full potential. As a global biopharmaceutical leader, our focus is exclusively on brain disorders. The Lundbeck La Jolla Research Center serves as our North American hub for pioneering drug discovery, positioning us to deliver...


  • South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...


  • South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?You've worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world's leading...


  • San Mateo, California, United States Gilead Sciences Full time

    Job OverviewAt Gilead Sciences, we are dedicated to fostering a healthier world for everyone. With over 35 years of experience, we have been at the forefront of addressing critical health issues such as HIV, viral hepatitis, COVID-19, and cancer. Our commitment to developing innovative therapies is unwavering, and we strive to ensure these solutions are...


  • South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology...

  • Research Scientist

    2 weeks ago


    San Diego, California, United States Lundbeck Full time

    Are you interested in contributing to a mission that is impactful, tackling intricate challenges, and witnessing the outcomes of your efforts? At Lundbeck, our unwavering commitment is to restore brain health, enabling individuals to reach their full potential. As a unique global biopharmaceutical entity dedicated solely to brain disorders, Lundbeck's North...


  • South San Francisco, California, United States SonoThera Full time

    About SonoThera: SonoThera is a venture backed early stage highly innovative biopharmaceutical company that has developed a novel ultrasound-guided non-viral gene therapy platform to provide patients with the next generation of genetic medicines. Our platform can precisely and non-invasively target almost any organ in the body to deliver very large payloads...


  • South San Francisco, California, United States Amgen Full time

    HOW MIGHT YOU DEFY IMAGINATION?If you feel like youre part of something bigger, its because you are. At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies. We are global collaborators who achieve togetherresearching, manufacturing, and delivering ever-better products...


  • San Francisco, California, United States Parvus Therapeutics, Inc. Full time

    About the RoleWe are seeking a highly experienced Associate Director to lead our In Vivo Pharmacology Team and manage projects enabling the development of Navacims towards clinical evaluation. This role will also establish research and discovery efforts to foster our Parvus product pipeline growth.Key ResponsibilitiesDevelop and Conduct Immunological Models:...


  • San Francisco, California, United States Altos Labs Full time

    About the RoleWe are seeking a highly motivated and experienced Senior Scientist to join our In Vitro Pharmacology team at Altos Labs. As a key member of our team, you will be responsible for developing and optimizing in vitro and cellular assays for AAV gene therapy.Key ResponsibilitiesLead the development and optimization of in vitro and cellular assays...


  • South San Francisco, California, United States Rose International Full time

    Job SummaryWe are seeking a highly motivated and experienced Translational Research Scientist to join our team at Rose International. As a key member of our Translational Medicine department, you will play a crucial role in driving the development of new medicines and accelerating drug development timelines.Key ResponsibilitiesDesign, perform, and analyze in...


  • San Francisco, California, United States Altos Labs Full time

    Our MissionAt Altos Labs, we are dedicated to restoring cellular health and resilience through innovative rejuvenation techniques aimed at reversing diseases, injuries, and age-related disabilities. Our Core ValueWe embrace a singular Altos Value: Everyone is Responsible for Achieving Our Inspiring Mission.Diversity at AltosWe recognize that diverse...


  • San Diego, California, United States AnaptysBio Inc Full time

    Job SummaryAnaptysBio Inc is seeking a highly skilled Senior Scientist, Translational Pharmacology Specialist to join our team. As a key member of our translational pharmacology group, you will be responsible for designing, performing, interpreting, and recording in vitro cellular functional assays with lead candidate antibodies to achieve program goals.Key...


  • San Francisco, California, United States Altos Labs Full time

    Our MissionAt Altos Labs, we are dedicated to enhancing cellular health and resilience through innovative rejuvenation techniques aimed at reversing diseases, injuries, and age-related disabilities. Our Core ValueWe uphold a singular Altos Value: Collective Responsibility for Achieving Our Inspiring Mission.Diversity at AltosWe recognize that diverse...


  • South San Francisco, California, United States Amgen Foundation, Inc. Full time

    About the RoleWe are seeking a highly motivated and experienced Senior Research Scientist to join our Pharmacokinetics & Drug Metabolism (PKDM) department at our site in South San Francisco, California.The successful candidate will work in a team environment to characterize the absorption, distribution, metabolism, excretion and pharmacokinetic properties of...