Senior Scientist, Inflammation

1 month ago


South San Francisco, California, United States Amgen Full time

HOW MIGHT YOU DEFY IMAGINATION?

Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Senior Scientist, InflammationLive

What you will do

Lets do this. Lets change the world. The Department of Inflammation at AMGEN Inc. is currently seeking a dedicated senior scientist to contribute to our research efforts in developing new treatments for inflammatory and autoimmune diseases. This role requires a commitment to developing a deep understanding of the pathogenic mechanisms that underlie inflammation. In this vital role, you will be driving discovery efforts to identify how Amgens innovative modalities can improve the lives of patients who suffer from inflammatory and autoimmune diseases and related co-morbidities.Key Responsibilities:Identification of new therapeutic targets and preclinical validation. The candidate is expected to be continuously aware of scientific developments in immunology, inflammatory diseases and the constantly evolving landscape of unmet needs in patients with inflammatory disease.Work collaboratively with a team of expert scientists.Present research discoveries to AMGEN colleagues and scientific meetings (oral or poster presentations and publish scientific papers in peer-reviewed journals).Lead ethical, high-quality research experiments in accordance with regulatory agencies and compliance guidelines.Design or assist in the development of medium to low-throughput assays used to support both small and large molecule drug development programs.Independently design, perform, and analyze in vitro, ex vivo, in silico and in vivo laboratory experiments, including troubleshooting, optimization of assays, data collection, interpretation, biostatistical analysis, and presentation.It is critical that the candidate is familiar with immunology-related techniques and assays.Participation in cross-functional drug development teams as a key intellectual and technical contributor.Function optimally in a team-based or collaborative environment as part of a highly integrated team, possess excellent organizational, verbal, and written communication skills, and demonstrate the ability to produce reliable and reproducible results.WinWhat we expect of you We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Sr. Scientist with these qualifications. Basic Qualifications:Doctorate degree orMasters degree and 3 years of relevant experience orBachelors degree and 5 years of relevant experiencePreferred Qualifications:PhD with a degree in biology or a related discipline.5 or more years of experience in immunolhgy-related research in industry or academic settings.Willing to work in a team environment and possess good laboratory documentation skills.Postdoctoral research experience.Ability to perform in vitro assays to dissect the mechanism of action of therapeutic molecules.In vitro experience with cultured cell lines, siRNA transfection techniques, CRISPR, western blotting, quantitative PCR techniques, RNA/DNA isolation, scRNAseq, laboratory automation, high-content imaging technology, and fluorescence microscopy.ThriveWhat you can expect of us As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being. Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including: Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.A discretionary annual bonus program, or for field sales representatives, a sales-based incentive planStock-based long-term incentivesAward-winning time-off plans and bi-annual company-wide shutdownsFlexible work models, including remote work arrangements, where possibleApply nowfor a career that defies imagination Objects in your future are closer than they appear. Join us. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.



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