Scientist, In Vivo Pharmacology

2 weeks ago

Cambridge, United States Vaxess Technologies Full time

Location: Cambridge, MA


Vaxess Technologies is developing next generation vaccines and therapies based on its proprietary MIMIXTM Microneedle Array Patch technology. MIMIXTM enables self-administration of vaccines and therapeutics to the skin with potential for improved shelf-stability, tolerability, and efficacy. We are committed to enabling products that are accessible to patients around the world. Research & development at Vaxess is cross-disciplinary, integrating biology, chemistry, immunology, materials science, and engineering to address important unmet medical needs in vaccines and therapeutics. We are seeking a talented, collaborative, and highly motivated individual with expertise in animal models, pharmacology and immunology to join our core team of scientists and engineers. This is a unique opportunity to be part of a thriving clinical-stage biotech company bringing innovative technology to the global market.


Responsibilities


  • Lead design of immunogenicity and pharmacokinetic studies, engaging key internal and external stakeholders in the process. Support the design of IND-enabling safety and efficacy studies.
  • Manage direct reports in the preclinical group. Organize personnel support and other key resources to ensure successful study outcomes. Provide hands-on study support and cross-training as needed.
  • Manage external animal studies at CROs and ensure proper tech transfer of materials and protocols.
  • Engage with internal teams in research and early development, defining the questions critical for platform animal model and device development.
  • Present results in internal and external meetings and lead scientific report writing.
  • Develop or improve organizational tools to collate in vivo study endpoints for team-wide visibility.
  • Ensure compliance with IACUC and facilitate training and credentialing for new staff members.


Qualifications


  • PhD with 1-3 years of experience or BS/MS with at least 5 years of experience in pharmacology, biology, or related field of study in the biotech or pharmaceutical industry
  • Experience with pharmacokinetic and pharmacodynamic (PK/PD) study design and analysis is required
  • Hands-on experience with a variety of rodent models, including mice and rats, and experience managing or executing large animal experiments in swine or non-human primates
  • Proficiency interpreting clinical signs and basic animal health screening data
  • Experience training junior staff on various administration and blood sampling techniques
  • Familiarity with IACUC review and approval processes
  • Excellent verbal and written communication skills
  • Committed to working collaboratively with an interdisciplinary cross-functional team


Vaxess, a venture-backed clinical-stage life sciences company, is building a team of exceptional people to rapidly advance products on the MIMIXTM platform. We work closely as a team and thrive in a dynamic, exciting, and engaging work environment. If you’re interested in joining the Vaxess team, please submit your CV/resume to careers@vaxess.com.

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