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Scientist, In Vivo Pharmacology
3 months ago
Location: Cambridge, MA
Vaxess Technologies is developing next generation vaccines and therapies based on its proprietary MIMIX™ Microneedle Array Patch technology. MIMIX™ enables self-administration of vaccines and therapeutics to the skin with potential for improved shelf-stability, tolerability, and efficacy. We are committed to enabling products that are accessible to patients around the world.
Research & development at Vaxess is cross-disciplinary, integrating biology, chemistry, immunology, materials
science, and engineering to address important unmet medical needs in vaccines and therapeutics. We are seeking a talented, collaborative, and highly motivated individual with expertise in animal models, pharmacology and
immunology to join our core team of scientists and engineers. This is a unique opportunity to be part of a thriving clinical-stage biotech company bringing innovative technology to the global market.
Responsibilities
- Lead design of immunogenicity and pharmacokinetic studies, engaging key internal and external stakeholders in the process. Support the design of IND-enabling safety and efficacy studies.
- Manage direct reports in the preclinical group. Organize personnel support and other key resources to ensure successful study outcomes. Provide hands-on study support and cross-training as needed.
- Manage external animal studies at CROs and ensure proper tech transfer of materials and protocols.
- Engage with internal teams in research and early development, defining the questions critical for platform animal model and device development.
- Present results in internal and external meetings and lead scientific report writing.
- Develop or improve organizational tools to collate in vivo study endpoints for team-wide visibility.
- Ensure compliance with IACUC and facilitate training and credentialing for new staff members.
Qualifications
- PhD with 1-3 years of experience or BS/MS with at least 5 years of experience in pharmacology, biology, or related field of study in the biotech or pharmaceutical industry
- Experience with pharmacokinetic and pharmacodynamic (PK/PD) study design and analysis is required
- Hands-on experience with a variety of rodent models, including mice and rats, and experience managing or executing large animal experiments in swine or non-human primates
- Proficiency interpreting clinical signs and basic animal health screening data
- Experience training junior staff on various administration and blood sampling techniques
- Familiarity with IACUC review and approval processes
- Excellent verbal and written communication skills
- Committed to working collaboratively with an interdisciplinary cross-functional team
Vaxess, a venture-backed clinical-stage life sciences company, is building a team of exceptional people to rapidly advance products on the MIMIX™ platform. We work closely as a team and thrive in a dynamic, exciting, and engaging work environment. If you’re interested in joining the Vaxess team, please submit your CV/resume to careers@vaxess.com.
