Current jobs related to Lead Scientist, Quantitative Clinical Pharmacology - Cambridge, Massachusetts - UCB
-
Senior Director, Quantitative Pharmacology Lead
2 weeks ago
Cambridge, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob Title: Senior Director, Quantitative PharmacologyRegeneron Pharmaceuticals is seeking a highly skilled Senior Director, Quantitative Pharmacology to join our team. As a key member of our Pharmacometrics group, you will be responsible for managing PMx support for multiple programs across various therapeutic areas.Key Responsibilities:Develop and implement...
-
Senior Quantitative Pharmacology Director
2 days ago
Cambridge, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob SummaryWe are seeking a highly skilled Associate Director, Quantitative Pharmacologist to support our research and development projects. The successful candidate will leverage their expertise in Quantitative Pharmacology to develop and implement strategic analyses, ensuring the highest quality and accuracy of analyses and documentation.Key...
-
In Vivo Pharmacology Expert
2 weeks ago
Cambridge, Massachusetts, United States Third Rock Ventures Full timeAssociate Scientist/Scientist, In Vivo PharmacologyWe are seeking a highly skilled Associate Scientist/Scientist to join our Biology-In Vivo Pharmacology team at Third Rock Ventures. As a key member of our team, you will serve as the in vivo pharmacology representative for discovery-stage pipeline programs focused on antibody-driven diseases.Key...
-
Cambridge, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob SummaryRegeneron Pharmaceuticals is seeking a highly skilled Senior Director, Quantitative Pharmacology to join our team. In this role, you will be responsible for managing PMx support for a number of programs in one or more therapeutic focus areas of the development portfolio.Key ResponsibilitiesDevelop and implement strategic analyses in support of...
-
Quantitative Pharmacology Director
1 week ago
Cambridge, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob Title: Associate Director, Quantitative PharmacologistWe are seeking a highly motivated Associate Director to join our team in Quantitative Pharmacology (QP). The successful candidate will be responsible for providing hands-on pharmacometrics support in one or more therapeutic focus areas.Key Responsibilities:Develop and implement strategic analyses in...
-
Quantitative Pharmacology Director
2 days ago
Cambridge, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob SummaryWe are seeking a highly motivated Associate Director in Quantitative Pharmacology to provide hands-on pharmacometrics support in one or more therapeutic focus areas.The successful candidate will be responsible for the successful and timely completion of QP-related activities, encompassing a broad array of deliverables.Key ResponsibilitiesDevelop...
-
Senior Director of Quantitative Pharmacology
2 weeks ago
Cambridge, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob SummaryWe are seeking a highly skilled Senior Director of Quantitative Pharmacology to join our team at Regeneron Pharmaceuticals. As a key member of our Pharmacometrics group, you will be responsible for managing PMx support for multiple programs across various therapeutic areas.Key ResponsibilitiesDevelop and implement strategic analyses to support...
-
Cambridge, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob SummaryWe are seeking a highly skilled Associate Director to lead our Quantitative Pharmacology team. As a key member of our research and development team, you will be responsible for providing expert-level pharmacometrics support to our therapeutic focus areas.Key ResponsibilitiesDevelop and implement strategic analyses to support research and...
-
Senior Quantitative Pharmacology Director
2 days ago
Cambridge, Massachusetts, United States Regeneron Pharmaceuticals Full timeJob DescriptionWe are seeking a highly motivated Associate Director in Quantitative Pharmacology to provide hands-on pharmacometrics support in one or more therapeutic focus areas.Key Responsibilities:Provide expert-level pharmacometrics support to research and development projects.Develop and implement strategic analyses to support research and development...
-
Cambridge, Massachusetts, United States Healthcare Businesswomen's Association Full timeJob Title: Research Scientist, Kidney PharmacologyWe are seeking a highly skilled Research Scientist to join our team in the Kidney Pharmacology department. The successful candidate will be responsible for designing and implementing in vivo and ex vivo studies to identify new therapeutic targets for renal diseases.Key Responsibilities:Conduct in vivo...
-
Research Scientist, Kidney Pharmacology
2 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Title: Research Scientist, Kidney PharmacologyJob Summary:We are seeking a highly motivated Research Scientist to join our interdisciplinary Discovery and Translational Pharmacology group in support of our efforts to progress novel medicines toward the clinic. This role will involve designing and implementing in vivo and ex vivo studies to identify new...
-
Research Scientist Cell Pharmacology
2 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Title: Research Scientist, Cell PharmacologyWe are seeking a highly motivated Research Scientist to join our Cell Pharmacology team at Novartis. As a key member of our team, you will contribute to advancing our understanding of disease biology, support target identification efforts, and work towards the discovery and optimization of new drugs for CVM.Key...
-
Principal Scientist
7 days ago
Cambridge, Massachusetts, United States Delphia Therapeutics Full timeAbout Delphia TherapeuticsDelphia Therapeutics is a biotechnology company pioneering a new field of cancer biology, Activation Lethality, to develop targeted cancer medicines that provide better outcomes for patients.The RoleWe are seeking a Principal Scientist / Associate Director, In Vivo Pharmacology to join our team and lead the development and execution...
-
Research Scientist Cell Pharmacology
3 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Title: Research Scientist, Cell PharmacologyWe are seeking a highly motivated Research Scientist to join our Cell Pharmacology team at Novartis Group Companies.About the Role:This is an exciting opportunity to advance our understanding of disease biology, contribute to target identification efforts, and work towards the discovery and optimization of new...
-
Cambridge, Massachusetts, United States Novartis International AG Full timeJob SummaryWe are seeking a highly skilled and experienced Senior Principal Scientist, Pharmacology to join our dynamic, multi-disciplinary team. As a key member of our team, you will play a crucial role in developing and applying in vivo models to evaluate novel cancer therapies in the early-stage drug discovery pipeline.Key ResponsibilitiesDevelop and...
-
Senior Scientist, Radioligand Modeling
4 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeAbout the RoleWe are seeking a highly skilled and experienced Translational or Clinical Modeler to accelerate radioligand discovery and development by facilitating rigorous decision-making with modeling and simulation. As a key member of our team, you will work in a multi-disciplinary environment, collaborating with cross-functional initiatives to drive...
-
Research Scientist
2 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Description SummaryWe are seeking a highly motivated Research Scientist to join our Cell Pharmacology team. The successful candidate will contribute to advancing our understanding of disease biology, target identification efforts, and the discovery and optimization of new drugs for CVM.Key Responsibilities:Support target identification, validation, and...
-
Research Scientist
7 days ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Description SummaryNovartis Group Companies is seeking a highly motivated Research Scientist to join our Cell Pharmacology team. The successful candidate will contribute to advancing our understanding of disease biology, target identification efforts, and the discovery and optimization of new drugs for CVM. The role involves collaboration with research...
-
Research Scientist, Cell Pharmacology Expert
1 week ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Title: Research Scientist, Cell PharmacologyWe are seeking a highly motivated Research Scientist to join our Cell Pharmacology team at Novartis. As a key member of our team, you will contribute to advancing our understanding of disease biology, target identification efforts, and the discovery and optimization of new drugs for CVM.Key...
-
Research Scientist, Kidney Pharmacology
2 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Description SummaryWe are seeking an innovative scientist to join our interdisciplinary Discovery and Translational Pharmacology group in support of our efforts to progress novel medicines toward the clinic. This role will involve designing and implementing in vivo and ex vivo studies to identify new therapeutic targets, with a focus on renal diseases,...
Lead Scientist, Quantitative Clinical Pharmacology
2 months ago
POSITION OVERVIEW
As a key member of our team, the Lead Scientist - Quantitative Clinical Pharmacology / PK-PD Specialist will concentrate on quantitative clinical pharmacology initiatives across various diseases and therapeutic domains. This role is pivotal in advancing both Early and Late Clinical Development at UCB, collaborating with cross-functional experts to formulate a comprehensive clinical development strategy. You will take charge of leading and executing an integrated PK-PD strategy (focusing on safety and efficacy) for designated projects, guiding the process from candidate selection through to lifecycle management.
Your responsibilities will include:
- Serving as the QCP/PK-PD lead on assigned Clinical Teams and project groups, ensuring that strategic QCP/PK-PD guidance is provided for study plans, designs, dose selections, and relevant operational insights.
- Engaging in Model-Based Drug Development to tackle complex challenges throughout the drug development process, ensuring the integration of PK-PD knowledge on an ongoing basis.
- Assuming the role of Development Scientist lead for the designated project when appropriate.
- Overseeing non-compartmental analysis of PK data, ensuring that essential PK-PD data is generated and analyzed, including population PK, PK-PD modeling, and simulation.
- Offering recommendations for clinical dosing and leading the quantitative clinical pharmacology contributions to regulatory documentation.
- Cultivating and sustaining relationships with external thought leaders and partners in the pharmaceutical sector, ensuring the publication of significant clinical pharmacology studies in reputable journals and presentations at relevant scientific conferences.
- M.D. and/or Ph.D. in a relevant scientific discipline.
- Experience in developing clinical plans with a focus on clinical pharmacology components, including regulatory considerations.
- Comprehensive understanding of pharmacodynamics, translational methods, and population pharmacokinetic-pharmacodynamic modeling.
The ideal candidate will possess essential clinical scientific skills, including:
- Proficiency in Clinical Pharmacology and the application of Modeling & Simulation.
- Ability to interpret clinical effects and understand pharmacological, physiological, and biochemical principles.
- Familiarity with in vivo/in vitro pharmacology.
- Experience in managing PK/PD modeling activities and understanding drug interactions.
- General knowledge of Biopharmaceutics, Biostatistics, and Pharmacogenomics.
The candidate should also demonstrate:
- Strong communication skills to convey quantitative clinical pharmacology activities effectively.
- Capability to contribute to interdisciplinary team discussions and lead sub-teams when necessary.
- Proactive problem-solving abilities and the capacity to anticipate program needs.
- Recognition as a scientific expert both internally and externally.
At UCB, we are committed to fostering an inclusive environment where every individual can thrive and contribute to our mission of creating value for patients.
As an Equal Opportunity Employer, we welcome diverse talent and adhere to principles of Affirmative Action, ensuring that all qualified applicants receive equal consideration for employment.
