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Senior Research Associate
2 months ago
Job Title: Senior Research Associate
Job ID: 24-03074
Location: Seattle-Dexter, WA, 98109
Duration: 12 Months contract on W2
* Hybrid - The GDEPD department adheres to an 80% onsite requirement for all lab based employees. This gives employees the flexibility to work at home 1 day per week.
*Top Skills:
- Experience with downstream processes development e.g. chromatography, filtration, TFF development, process-analytical technology (PAT)
- Experience with chromatography operation
- Experience with harvest filtration operation of biologics and/or viral vectors
- Experience with tangential flow filtration(TFF) or ultrafiltration/diafiltration(UF/DF) operation
- Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing
The associate will join the LVV Platform Development team working on vector biology and molecular optimization initiatives intended to drive next-generation viral vector platform development. Specifically, in the pursuit of end-to-end assessment of Client technologies and approaches, the associate will seek to become highly proficient in downstream purification of lentiviral vectors, while gaining familiarity with LVV analytical methods and their interpretation in the context of LVV attributes and biology. The associate will also have the unique opportunity to be exposed to a wide range of highly Client molecular designs, and to work collaboratively with a range of different groups doing different types of LVV development.
Basic Qualifications:
- STEM degree with 2+ years of relevant industry experience; title/compensation will ultimately be commensurate with education, experience, and skillset
- Experience with purification of biologics (mAbs, fc-fusion proteins) or viral vectors
- Hands on experience in biologics process development
- Independently motivated with ability to work in teams
- Ability to communicate clearly and concisely through oral presentation and technical writing
- Ability to leverage literature, internal and external resources to solve problems
Preferred Qualifications:
- Degree in biological, biomedical, or chemical engineering, biochemistry, or bio-related field
- Experience with AKTA chromatography skid operation
- Experience with tangential flow filtration or ultrafiltration/diafiltration operation
- Experience with depth filtration operation
- Experience with JMP for DoE design and analysis
- Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing
- Experience with mammalian cell culture operation
- Experience with downstream platform processes development e.g. chromatography resin screens, TFF flux excursions, depth filter screens.
The hourly rate for this position is between $54.00 – $59.00 per hour.
Compensation:
Factors that may affect starting pay within this range may include [geography/market, skills, education, experience, and other qualifications of the successful candidate].
Benefits:
Sunrise offers ACA-compliant medical coverage/dental insurance/vision insurance to all employees. We also offer Sick time benefits as required per State regulations.
