Senior Associate Scientist, Translational Medicine and Biomarkers Imaging
2 weeks ago
About the Position
The Translational Medicine Biomarkers Imaging division at Biogen is at the forefront of a cutting-edge molecular imaging research initiative. This program focuses on the identification and evaluation of radiotracers and methodologies crucial for drug development. We are in search of a dedicated scientist with expertise in pharmacology techniques, both plate-based and tissue-based, utilizing radioligands in various biological systems, both in vitro and in vivo. This role is primarily laboratory-focused (80-90%) and requires close collaboration with Imaging team members and other program teams.
Key Responsibilities
- Assess the pharmacological properties of leading small molecules in vitro and in vivo using diverse molecular imaging techniques.
- Employ radiolabeled compounds such as [3H] and [18F] to conduct molecular pharmacology assays.
- Perform in vitro and ex vivo radioligand binding studies for plate-based and autoradiographic brain imaging.
- Process human and rodent tissues, including cryostat brain slicing and homogenate preparation for protein target isolation.
- Develop and optimize assays and methodologies for plate-based and ex vivo brain imaging studies.
- Handle animals, including brain dissection and administration of compounds or radioisotopes.
- Utilize target identification techniques through immunohistochemistry (IHC) and immunofluorescence.
- Present findings at team meetings and internal group discussions.
Who You Are
You are a highly driven and results-focused scientist with excellent communication skills, thriving in a collaborative setting. You will contribute to a team of scientists dedicated to the preclinical discovery of innovative Biomarker PET tracers for clinical trials targeting neurological disorders.
Qualifications
- Bachelor's degree with a minimum of 4-6 years of industry experience in pharma/biotech or CRO, or a Master's degree with at least 2-4 years of relevant experience.
- Proficiency in plate-based pharmacology techniques.
- Experience in compound handling and solution preparation.
- Knowledge of radioisotope handling.
- Experience in assay development and optimization.
- Competence in rodent handling, compound dosing, and tissue dissection.
- Familiarity with immunohistochemistry (IHC) techniques for target detection in brain tissues.
Preferred Qualifications
- Understanding of therapeutic areas related to neurology, particularly neurodegenerative diseases.
Why Join Biogen?
At Biogen, we are a global team committed to excellence and innovation. As a mid-sized biotechnology firm, we offer the stability and resources of an established organization while promoting an environment where individual contributions are valued. Our team consists of some of the most talented and passionate professionals, providing unparalleled opportunities for learning, growth, and skill enhancement. Together, we strive to deliver transformative medicines, with every role playing a crucial part in our mission. We are dedicated to fostering a culture of inclusion and belonging that reflects the diverse communities we serve. We believe that varied backgrounds, cultures, and perspectives strengthen our company and drive innovation.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by federal, state, or local law.
-
Cambridge, Massachusetts, United States Biogen Full timePosition OverviewBiogen's Translational Medicine Biomarkers Imaging division is at the forefront of a cutting-edge molecular imaging research initiative, focusing on the discovery and evaluation of radiotracers and methodologies applicable to drug development.Key ResponsibilitiesWe are in search of a dedicated scientist with a strong background in both...
-
Cambridge, Massachusetts, United States Biogen Full timePosition OverviewWe invite you to explore the opportunity to join Biogen's esteemed Translational Medicine Biomarkers Imaging team. This role is pivotal in advancing our innovative molecular imaging research initiatives, focusing on the development and assessment of radiotracers and methodologies essential for drug discovery.Key ResponsibilitiesAs a vital...
-
Cambridge, Massachusetts, United States BlueRock Therapeutics Full timeAbout the RoleWe are seeking a highly skilled Director of Imaging and Biomarkers, Translational Medicine to join our team at BlueRock Therapeutics. As a critical member of our Translational Medicine team, you will leverage your expertise in CNS, ophthalmic, and inflammation imaging to advance our development pipeline.Key ResponsibilitiesDevelop Translational...
-
Cambridge, Massachusetts, United States BlueRock Therapeutics Full timeDirector of Imaging and Biomarkers, Translational MedicineBlueRock Therapeutics, a premier engineered cell therapy organization under Bayer AG, is at the forefront of utilizing its innovative cell+gene platform to facilitate cellular differentiation and genetically modify cells, aiming to pioneer a new era of cellular therapies that cater to extensive...
-
Cambridge, Massachusetts, United States BlueRock Therapeutics Full timeDirector of Imaging and Biomarkers, Translational MedicineBlueRock Therapeutics, a pioneering entity under Bayer AG, stands at the forefront of engineered cell therapy, utilizing a distinctive cell+gene platform to guide cellular differentiation and genetically modify cells, paving the way for a new era of cellular medicines aimed at addressing widespread...
-
Cambridge, Massachusetts, United States BlueRock Therapeutics Full timeDirector of Imaging and Biomarkers in Translational MedicineBlueRock Therapeutics, a pioneering entity under Bayer AG, stands at the forefront of engineered cell therapy, utilizing a distinctive cell+gene platform to guide cellular differentiation and genetically modify cells, thereby crafting a new era of cellular medicines aimed at extensive patient...
-
Cambridge, Massachusetts, United States BlueRock Therapeutics Full timeAbout the RoleWe are seeking a highly skilled Director of Imaging and Biomarkers to join our Translational Medicine team at BlueRock Therapeutics. As a critical member of our team, you will leverage your expertise in CNS, ophthalmic, and inflammation imaging to advance our development pipeline.Key ResponsibilitiesDevelop Translational Strategies: Design and...
-
Cambridge, Massachusetts, United States Biogen Full timeAbout This Position The Translational Medicine Biomarkers Imaging team at Biogen is at the forefront of pioneering research in molecular imaging. We are dedicated to the exploration and development of innovative radiotracers and advanced methodologies that enhance our understanding of various medical conditions. Key Responsibilities Engage in...
-
Senior Director, Translation Imaging Lead
3 days ago
Cambridge, Massachusetts, United States Bayer Full timeAbout the RoleWe are seeking a highly experienced and skilled Senior Director, Translation Imaging Lead to join our team at Bayer. As a key member of our Clinical Development organization, you will play a critical role in driving the development of our clinical and biomarkers imaging portfolio.Key ResponsibilitiesDevelop and implement strategic guidance for...
-
CNS Biomarker Research Scientist
2 weeks ago
Cambridge, Massachusetts, United States QurAlis Full timeABOUT QURALISQurAlis is at the forefront of neurobiology, striving to revolutionize the treatment landscape for neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our foundation is built on a team of esteemed neurobiologists from Harvard Medical School and Harvard University, dedicated to the discovery...
-
CNS Biomarker Research Scientist
7 days ago
Cambridge, Massachusetts, United States QurAlis Full timeABOUT QURALISQurAlis is at the forefront of neurodegenerative research, dedicated to pioneering solutions for conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our mission is driven by a commitment to scientific excellence and innovative approaches to develop precision medicines that can transform patient outcomes. Our...
-
CNS Biomarker Research Scientist
1 week ago
Cambridge, Massachusetts, United States QurAlis Full timeABOUT QURALISQurAlis is at the forefront of neurobiology, dedicated to pioneering innovative solutions for neurodegenerative diseases. Our mission is to develop precise therapeutic interventions that significantly impact conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). With a foundation built by esteemed...
-
CNS Biomarker Research Scientist
2 weeks ago
Cambridge, Massachusetts, United States QurAlis Full timeABOUT QURALISQurAlis is at the forefront of neurodegenerative research, striving to develop innovative therapies. Our team is driven by a commitment to scientific excellence and a vision to transform the treatment landscape for conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our foundation is built upon the expertise...
-
Senior Scientist, Translational Research
1 week ago
Cambridge, Massachusetts, United States Bristol Myers Squibb Full timeJoin Our Team At Bristol Myers Squibb, we offer a unique opportunity to engage in work that is both challenging and impactful. Our environment fosters innovation and collaboration, where every team member contributes to transformative advancements in patient care. Here, you will find a place to grow your career alongside a diverse group of high-achieving...
-
Senior Scientist, Expert in Molecular Imaging
2 weeks ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timePosition OverviewThe Biomarker Development (BMD) division at Novartis BioMedical Research is in search of a Molecular Imaging Specialist to enhance our Clinical Imaging & Analytics team. This role involves providing strategic, scientific, technical, and operational guidance on the effective application of imaging in pharmaceutical development.This position...
-
CNS Biomarker Research Scientist
2 weeks ago
Cambridge, Massachusetts, United States QurAlis Full timeABOUT QURALISQurAlis is at the forefront of neurodegenerative research, dedicated to the development of innovative precision therapies aimed at transforming the treatment landscape for conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our team, composed of leading experts from prestigious institutions, is committed to...
-
Neuroscience Biomarker Researcher
1 week ago
Cambridge, Massachusetts, United States QurAlis Full timeABOUT QURALISQurAlis is at the forefront of neurodegenerative research, dedicated to pioneering innovative solutions for conditions such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our team, composed of esteemed neurobiologists from prestigious institutions, is committed to advancing precision medicine through rigorous...
-
Lead Scientist, Biomarker Development
5 days ago
Cambridge, Massachusetts, United States Novartis Farmacutica Full timeJob SummaryWe are seeking a highly skilled Senior Research Scientist to join our Clinical Genetics and Genomics team at Novartis Farmacutica. As a key member of our team, you will be responsible for developing and implementing innovative genetic and genomic biomarker assays, including targeted and NGS-based technologies.Key ResponsibilitiesDevelop, validate,...
-
Senior Manager, Oncology Clinical Biomarkers
2 weeks ago
Cambridge, Massachusetts, United States Moderna Therapeutics Full timePosition Overview:Moderna Therapeutics is on the lookout for a Senior Manager specializing in Clinical Biomarkers to spearhead and implement biomarker strategies across our clinical Oncology initiatives. This role will report directly to the Associate Director of Oncology, Clinical Biomarkers.The Senior Manager will collaborate closely with both internal...
-
Cambridge, Massachusetts, United States Moderna, Inc. Full timeThe Role:Moderna is seeking a Clinical Biomarker leader to drive biomarker assay plans across clinical stage oncology programs. This position reports to Modernas Director of Clinical Biomarkers. The Associate Director will work collaboratively across several clinical teams(internal, external CROs) to ensure biomarker assay development strategy, planning,...
