Senior Formulation Engineer

1 day ago


Menlo Park, California, United States ReCode Therapeutics Full time
About the Role

We are seeking a highly skilled and motivated Senior Formulation Engineer to join our team at ReCode Therapeutics. As a key member of our LNP Process Development team, you will play a critical role in the development of robust scalable LNP-encapsulated nucleic acids formulations and manufacturing processes.

Key Responsibilities
  1. Formulation Development: Execute studies to define formulation components, vehicle, and primary container.
  2. Lab Operations: Operate common biopharmaceutical unit operations such as mixing, dialysis, tangential flow filtration, and sterile filtration.
  3. Process Optimization: Support efforts in fill/finish process optimization, process characterization, technology transfer, and regulatory documentation for our LNP formulations candidates.
  4. Collaboration and Communication: Interface with External Manufacturing, Quality and Regulatory organizations to execute on strategies for GLP or GMP batches.
  5. Characterization and Troubleshooting: Perform in-process characterization such as pH, particle size, encapsulation efficiency measurement etc. and support troubleshooting and technical investigations as needed.
  6. Pre-Formulation Assessments: Manage daily pre-formulation/material assessments of LNP screening and development.
  7. Documentation and Record-Keeping: Maintain thorough and detailed electronic lab notebooks and documentation records.
  8. Presentations and Meetings: Support and participate in R&D and project management meetings. Prepare PowerPoint slides and present your findings to multi-disciplinary teams.
  9. Lab Safety and Maintenance: Adhere to all laboratory safety requirements and procedures. Assist in maintaining general laboratory functionality and lab equipment.
  10. Supply Chain Management: Assist in ordering and receiving of lab supplies.
Requirements
  1. Education: S. or M.S. chemical engineering, bioengineering, pharmaceutical sciences.
  2. Foundation in Chemistry: Foundation in chemistry, materials science, bio-engineering, chemical engineering, or related field.
  3. Communication Skills: Strong written and oral communication skills, comfort with a "start-up environment".
  4. CAD Software: Familiarity using CAD software such as Solidworks AutoCAD is an advantage.
What We Offer
  1. Competitive Salary: $115,000 - $135,000.
  2. Benefits Package: No premium cost for employees - 100% subsidized by ReCode for full-time employees. Company 401k contribution. 15 days of company paid holidays, including a holiday shutdown (usually the last week of the year). Mental health support for employees & their families. FSA available, including a lifestyle spending account subsidized by company. Employee discounts at hotspots.


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