Senior Bioanalytical Scientist

3 days ago

Wilmington, Delaware, United States Incyte Full time
Job Title: Senior Bioanalytical Scientist

Join Incyte's Bioanalysis team as a Senior Bioanalytical Scientist and contribute to the discovery, development, and commercialization of novel medicines in oncology and inflammation and autoimmunity.

About the Role

We are seeking a highly motivated and experienced bioanalytical scientist to provide strategic support to the discovery, nonclinical and clinical development of biologic drugs. As a Senior Bioanalytical Scientist, you will be an integral project team member representing Bioanalysis on biologics research projects to ensure delivery of high quality data within project timelines to support regulatory filings.

Key Responsibilities
  • Conduct bioanalytical method development and validation and sample analysis to support Incyte discovery and development programs.
  • Manage resources and prioritize studies in close communications with different groups including bioanalytical scientists, toxicology, pharmacology, DMPK, clinical PK, clinical operations, and clinical scientist.
  • Provide sample analysis in support of clinical, toxicology, DMPK, pharmacology, and other studies.
  • Provide data to pharmacokineticists, toxicokineticists, DMPK, line management, and project teams as needed.
  • Compliance with GLP and GCP regulations, follow company policies and SOPs, as applicable.
  • Closely working with Quality Assurance to ensure data quality and compliance, as applicable.
  • Review bioanalytical data and bioanalytical reports.
  • Contribute to clinical study reports and IND/NDA submission documents, as required.
  • Troubleshoot assay and instrumentation problems.
  • Train and assist junior scientists in the group on large molecule PK and Immunogenicity method optimization and troubleshooting.
  • Present study results to working group as needed.
  • Act as a bioanalytical phase Principle Investigator, if needed.
  • Manage bioanalytical studies at CROs, if required.
Qualifications
  • BS/MS/PhD degree or equivalent in Life Sciences or related discipline.
  • At least 10 years (BS) /7 years (MS)/5 year (PhD) related experience in pharmaceutical companies or CROs.
  • Knowledge of DMPK is required.
  • Strong hands-on experience in large molecule PK assays and Immunogenicity assays, including Anti-drug Antibody (ADA) and Neutralizing Antibody (NAb assays).
  • A broad knowledge of drug discovery and development, especially DMPK knowledge, is desirable.
  • Must have GLP and GCP knowledge and experience working in a regulated environment, if assigned tasks in regulated bioanalysis.
  • Excellent oral and written communication skills are essential along with strong organizational skills.

  • Senior Medical Laboratory Scientist

    1 week ago

    Wilmington, Delaware, United States MLee Healthcare Staffing and Recruiting, Inc Full time

    {"Job Title": "Lead Medical Laboratory Scientist", "Job Summary": "We are seeking a highly skilled and experienced Lead Medical Laboratory Scientist to join our team at MLee Healthcare Staffing and Recruiting, Inc. The successful candidate will be responsible for overseeing the operational and technical aspects of our laboratory section, ensuring the smooth...

  • Senior Data Scientist to Director, Data Insights

    3 weeks ago

    Wilmington, Delaware, United States Incyte Full time

    About the RoleIncyte, a leading biopharmaceutical company, is seeking a highly skilled Senior Data Scientist to join our team as Director, Data Insights. As a key member of our organization, you will play a critical role in driving business decisions and advancing our mission to improve the lives of patients.Key ResponsibilitiesData Science Leadership:...

  • Scientist for Polymer Characterization and Development

    3 weeks ago

    Wilmington, Delaware, United States International Flavors & Fragrances Full time

    Job DescriptionThe Pharma Solutions business is embarking on a new chapter of growth as a trusted partner for the pharmaceutical industry with the announcement to sell Pharma Solutions to Roquette. This move will position Pharma Solutions to expand its industry leadership through continued investment in innovation to meet the evolving needs of pharmaceutical...

  • Senior Scientist

    3 weeks ago

    Wilmington, Delaware, United States Solenis Full time

    About SolenisSolenis is a leading global producer of specialty chemicals focused on delivering sustainable solutions for water-intensive industries, including consumer, industrial, institutional, food and beverage, and pool and spa water markets.As a world-class company, we offer a broad array of water treatment chemistries, process aids, functional...

  • Polymer Applications and Analytical Research Scientist

    3 weeks ago

    Wilmington, Delaware, United States International Flavors & Fragrances Full time

    Job DescriptionThe Pharma Solutions business is embarking on a new chapter of growth as a trusted partner for the pharmaceutical industry with the announcement to sell Pharma Solutions to Roquette. This move will position Pharma Solutions to expand its industry leadership through continued investment in innovation to meet the evolving needs of pharmaceutical...

  • Senior Research Scientist

    2 weeks ago

    Wilmington, Delaware, United States Solenis Full time

    About SolenisSolenis is a leading global producer of specialty chemicals focused on delivering sustainable solutions for water-intensive industries. Our product portfolio includes a broad array of water treatment chemistries, process aids, functional additives, and cleaners and disinfectants, as well as state-of-the-art monitoring and control systems.Our...

  • Senior Research Scientist

    2 weeks ago

    Wilmington, Delaware, United States Solenis Full time

    About SolenisSolenis is a leading global producer of specialty chemicals focused on delivering sustainable solutions for water-intensive industries. Our product portfolio includes a broad array of water treatment chemistries, process aids, functional additives, and cleaners and disinfectants, as well as state-of-the-art monitoring and control systems.Our...

  • Lead Chromatography Scientist

    4 weeks ago

    Wilmington, Delaware, United States BIOTECHNOLOGY COMPANY Full time

    Position Overview:We are seeking a highly skilled and driven Senior Scientist specializing in Chromatography to join a leading Biotechnology Company. This role is pivotal in advancing our research and development initiatives in the field of analytical science.Location: Wilmington, DelawareKey Responsibilities:Lead and manage innovative research projects...

  • Senior Research Scientist

    4 weeks ago

    Wilmington, Delaware, United States The Azek Company Full time

    Job SummaryWe are seeking a highly skilled and experienced Senior Research Scientist to join our team at The Azek Company. As a key member of our Research and Development department, you will be responsible for leading major projects in developing PVC decking with high levels of recycled PVC resin in the formulations.Key ResponsibilitiesDevelop and implement...

  • Lead Chromatography Scientist

    4 weeks ago

    Wilmington, Delaware, United States BIOTECHNOLOGY COMPANY Full time

    Position Overview:We are seeking a highly qualified Senior Scientist with a Ph.D. in chemistry or a related discipline to take on the role of Lead Research Scientist specializing in chromatography and mass spectrometry. This position is critical for driving innovation and application development within our biotechnology firm.Location: Wilmington, DelawareKey...

  • Senior Organic and Polymer Research Scientist

    4 weeks ago

    Wilmington, Delaware, United States Ashland Global Specialty Chemicals, Inc. Full time

    Ashland Global Specialty Chemicals, Inc. Are you an innovative thinker who thrives on exploration and improvement? Do you possess a deep curiosity about the mechanisms of chemistry and a desire to enhance their applications? If you are a dedicated problem-solver who enjoys collaborating with like-minded professionals, we want to connect with you. We are...

  • Senior Chromatography Expert

    46 minutes ago

    Wilmington, Delaware, United States BIOTECHNOLOGY COMPANY Full time

    Job Title: Senior Scientist-PhD ChromatographyOur client, a Biotechnology firm, is seeking a skilled and motivated Analytical Scientist with a Ph.D. in chemistry or a related field, possessing strong chromatography and mass spectrometry (LCMS) skills.This role requires at least 10 years of bench experience and extensive practical application of separations,...

  • Business Development Director

    6 days ago

    Wilmington, Delaware, United States Sapient Bioanalytics LLC Full time

    About the Role:We are seeking a highly motivated and detail-oriented Business Development Director to join our growing commercial team within the life sciences industry. As a rapidly growing start-up, we value team members who can function highly in a fast-paced environment and think and work well independently.Responsibilities:Develop and execute strategic...

  • Senior Polymer Scientist

    3 weeks ago

    Wilmington, Delaware, United States International Flavors and Fragrances Full time

    Job SummaryWe have an exciting opportunity for a Senior Analytical Chemist to join our Designed Enzymatic Biomaterials (DEB) Polymer Characterization team at our Experimental Station site in the United States.The Polymer Characterization team is part of the Advanced Analytical-Biosciences group in the Health and Biosciences (H&B) business unit of...

  • Senior Research Scientist

    3 weeks ago

    Wilmington, Delaware, United States DuPont de Nemours, Inc. Full time

    About the RoleWe are seeking a highly skilled and experienced Principal Investigator to lead the development of new polymer formulations for the Semiconductor Packaging domain. As a key member of our global R&D team, you will work closely with Marketing, Sales, Regulatory, and Integrated Operations to bring innovative new products to market and support new...

  • Senior Risk Analytics Specialist

    4 weeks ago

    Wilmington, Delaware, United States OneMain Financial Full time

    Senior Risk Analytics SpecialistLocation: Wilmington, DE (Hybrid)We are looking for an exceptional professional to become a vital member of our Risk Development team. As a Senior Risk Analytics Specialist, you will be instrumental in the execution and enhancement of credit risk strategies and models across our proprietary systems and external partnerships....

  • Senior Fermentation Engineering Specialist

    4 weeks ago

    Wilmington, Delaware, United States IFF Full time

    Senior Engineer, Microbial Physiology and Fermentation Join the innovative team at IFF, where we combine expertise in taste, scent, nutrition, and biosciences to deliver exceptional natural solutions to our clients. As part of our Health and Biosciences division, you will play a crucial role in advancing microbial product development, bridging the gap...

  • Senior Fermentation Process Engineer

    4 weeks ago

    Wilmington, Delaware, United States International Flavors & Fragrances Full time

    Position OverviewAs a Lead Engineer specializing in Microbial Physiology and Fermentation, you will play a pivotal role in advancing our innovative capabilities at International Flavors & Fragrances. This position offers a unique opportunity to contribute to our mission of delivering exceptional solutions in the fields of taste, scent, nutrition, and...

  • Senior Research Scientist, Biologic Formulations

    2 weeks ago

    Wilmington, Delaware, United States Incyte Full time

    Job SummaryThe Principal Research Investigator will lead the development of novel formulations and manufacturing processes for monoclonal antibodies and bispecific biologic products at Incyte Corporation.Key ResponsibilitiesConduct research to develop formulations, manufacturing processes, and primary container configurations for biologic...

  • Senior Microbial Fermentation Specialist

    4 weeks ago

    Wilmington, Delaware, United States International Flavors & Fragrances Full time

    Position Overview:As a pivotal member of the Health and Biosciences division, the Lead Fermentation Engineer will spearhead the development and optimization of fermentation processes. This role is essential in bridging the gap between innovative discovery and efficient manufacturing.Key Responsibilities:Oversee and mentor a dedicated team of fermentation...