Current jobs related to Vice President, Immunology Translational Medicine - Watertown - Kymera Therapeutics, Inc.
-
Watertown, Massachusetts, United States Stratacuity: Proven Scientific Placement Full timeJob Title: Senior Vice President of Immunology and InflammationCompany: StratacuityLocation: Not specifiedFocus Area: Immunological DisordersPosition Overview: We are seeking an accomplished Senior Vice President to spearhead the advancement of groundbreaking oral degrader initiatives and manage translational immunology and inflammation endeavors. Leverage...
-
Watertown, United States Stratacuity: Proven Scientific Placement Full timeLocation: Watertown MA (Onsite)Science/Focus: Immunological DiseasesJob Overview: This role will lead the development of innovative oral degrader programs and oversee translational immunology and Inflammation projects, applying your expertise in immunology and Inflammation to drive progress and decision-making across our clients portfolio.Primary Job...
-
watertown, United States Stratacuity: Proven Scientific Placement Full timeLocation: Watertown MA (Onsite)Science/Focus: Immunological DiseasesJob Overview: This role will lead the development of innovative oral degrader programs and oversee translational immunology and Inflammation projects, applying your expertise in immunology and Inflammation to drive progress and decision-making across our clients portfolio.Primary Job...
-
Watertown, United States Stratacuity: Proven Scientific Placement Full timeLocation: Watertown MA (Onsite)Science/Focus: Immunological DiseasesJob Overview: This role will lead the development of innovative oral degrader programs and oversee translational immunology and Inflammation projects, applying your expertise in immunology and Inflammation to drive progress and decision-making across our clients portfolio.Primary Job...
-
Senior Immunology Director
4 weeks ago
Watertown, Massachusetts, United States Stratacuity: Proven Scientific Placement Full timeJob Title: Lead ImmunologistCompany: Stratacuity: Proven Scientific PlacementLocation: RemoteScience/Focus: Immunological DiseasesJob Overview: We are seeking a highly skilled Lead Immunologist to drive the development of innovative oral degrader programs and oversee translational immunology and inflammation projects. The ideal candidate will apply their...
-
Lead Immunologist and Translational Researcher
4 weeks ago
Watertown, Massachusetts, United States Stratacuity: Proven Scientific Placement Full timeJob Title: Lead ImmunologistCompany: Stratacuity: Proven Scientific PlacementLocation: Remote OpportunityScience/Focus: Immunological Diseases and Translational ResearchJob Overview: We are seeking a highly experienced Lead Immunologist to drive the development of innovative oral degrader programs and oversee translational immunology and inflammation...
-
Immunology and Inflammation Program Director
4 weeks ago
Watertown, Massachusetts, United States Stratacuity: Proven Scientific Placement Full time**Job Title:** Lead Immunologist**Company:** Stratacuity: Proven Scientific Placement**Location:** Remote Opportunity**Science/Focus:** Immunological Diseases and Translational Research**Job Overview:** We are seeking a highly experienced Lead Immunologist to drive the development of innovative oral degrader programs and oversee translational immunology and...
-
Watertown, Massachusetts, United States FMS USA Fresenius Mgmt Services Full timeRemote Opportunity: This position offers a fully remote work environment.PURPOSE AND SCOPE:The role is integral to advancing Fresenius Medical Care's mission, vision, core values, and commitment to exceptional customer service. Compliance with Fresenius Medical Care's regulatory framework and policy standards is paramount.KEY RESPONSIBILITIES:The Senior Vice...
-
Watertown, Massachusetts, United States Alloy Therapeutics Full timeCompany OverviewAlloy Therapeutics is a pioneering biotechnology ecosystem dedicated to empowering the global scientific community in the quest for superior medicines. By fostering a collaborative network of partners, we democratize access to essential pre-competitive tools, technologies, and services vital for the discovery and development of therapeutic...
-
Watertown, United States Alloy Therapeutics Full timeThe Company We are Alloy Therapeutics-a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic...
-
Watertown, Massachusetts, United States Alloy Therapeutics Full timeJob Title: Vice President of Antibody Discovery ProgramsAlloy Therapeutics is seeking a highly experienced and skilled Vice President of Antibody Discovery Programs to join our team in Waltham, MA. As a key member of our Antibody Discovery Services (ADS) team, you will play a pivotal role in shaping and leading strategies for our antibody discovery...
-
Vice President, Biostatistics
2 months ago
Watertown, United States Acrivon Therapeutics Full timeAcrivon is a clinical stage biopharmaceutical company developing precision oncology medicines that it matches to patients whose tumors are predicted to be sensitive to each specific medicine by utilizing Acrivon’s proprietary proteomics-based patient responder identification platform, Acrivon Predictive Precision Proteomics, or AP3. The AP3 platform is...
-
Watertown, Massachusetts, United States Alloy Therapeutics Full timeCompany OverviewAlloy Therapeutics is a pioneering biotechnology ecosystem dedicated to empowering the global scientific community in the quest for improved medicinal solutions. By fostering a collaborative network of partners, we democratize access to essential pre-competitive tools, technologies, and services crucial for the discovery and development of...
-
Vice President, Biostatistics
2 months ago
Watertown, United States Acrivon Therapeutics Full timeJob DescriptionJob DescriptionSalary: Acrivon is a clinical stage biopharmaceutical company developing precision oncology medicines that it matches to patients whose tumors are predicted to be sensitive to each specific medicine by utilizing Acrivon’s proprietary proteomics-based patient responder identification platform, Acrivon Predictive Precision...
-
Watertown, Massachusetts, United States Apellis Full timeJob SummaryWe are seeking a highly motivated and experienced scientist to join our Translational Development team at Apellis Pharmaceuticals, Inc. as a Postdoctoral Research Fellow in Translational Medicine. The successful candidate will play a crucial role in advancing our understanding of ocular diseases and developing therapeutic strategies for future...
-
Senior Scientist
3 weeks ago
Watertown, Massachusetts, United States Abata Therapeutics Full timeAbout UsAbata Therapeutics is a pioneering biotechnology company dedicated to developing innovative therapies for autoimmune diseases. Our mission is to transform lives by harnessing the power of regulatory T cells (Tregs) to restore homeostasis and enable a robust, durable response.The RoleWe are seeking an experienced and highly motivated Senior/Principal...
-
Vice President, Payer Sales
4 months ago
Watertown, United States Firefly Health Full timeJob DescriptionJob DescriptionBe a part of the team building the future of healthcare!Firefly Health delivers a refreshingly personal and convenient healthcare experience. Firefly works with payers and self-funded employers to offer advanced virtual-first primary care and virtual-first health plans that integrate care, coverage, and navigation, delivering...
-
Vice President of Operational Excellence
4 weeks ago
Watertown, Massachusetts, United States IASIS Healthcare Full timePosition Overview:The Vice President of Operational Excellence will collaborate closely with the Chief Operating Officer and executive leadership at IASIS Healthcare to spearhead organizational initiatives and bolster both clinical practices and administrative functions.This pivotal role aims to enhance clinical, operational, and financial outcomes by...
-
Investment Associate or Vice President
4 weeks ago
Watertown, Massachusetts, United States Windjammer Management Full timeCompany OverviewWindjammer Capital Investors is a distinguished private equity firm that specializes in acquiring control equity in middle-market enterprises. With a legacy dating back to 1990, the firm has successfully managed over $2 billion in committed capital, executing more than 60 platform investments and over 160 strategic add-ons. Our focus lies in...
-
Vice President of Operational Excellence
4 weeks ago
Watertown, Massachusetts, United States Markforged Full timeCompany OverviewMarkforged (NYSE: MKFG) is transforming the global manufacturing landscape, valued at over $1 trillion, enabling engineers to create anything they envision while minimizing environmental impact. With our cutting-edge 3D printing solutions, a dedicated team, esteemed clientele, and robust financial backing, we are poised for continued growth...
Vice President, Immunology Translational Medicine
4 months ago
Who we are:
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients' lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on delivering oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Kymera is also progressing degrader oncology programs that target undrugged or poorly drugged proteins to create new ways to fight cancer. Founded in 2016, Kymera has been recognized as one of Boston's top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.
How we work:
* PIONEER: We are courageous, resilient and rigorous in our mission to improve patients' lives through our revolutionary degrader medicines.
* COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
* BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.
How you'll contribute:
Reporting to the SVP, Translational Medicine, you will lead Translational Medicine efforts for Kymera's I/I portfolio, including our disclosed oral degrader programs in STAT6 (KT-621), TYK2 (KT-294), and Sanofi-partnered IRAK4 (KT-474).
* KT-621: In preclinical studies, KT-621, Kymera's first-in-class oral STAT6 degrader, demonstrated full inhibition of the IL-4/IL-13 pathway in all relevant human cell contexts with picomolar potency that was superior to dupilumab, and equivalent or superior efficacy to dupilumab in multiple preclinical efficacy studies.
* KT-294: In preclinical studies, KT-294 demonstrated picomolar to nanomolar potencies across all relevant human cell contexts evaluated, representing what Kymera believes is the only approach to TYK2 targeting that has the potential to recapitulate the human loss-of-function biology of near full pathway inhibition of Type I IFN, IL-12 and IL-23, while also sparing IL-10.
* KT-474: Following completion of Phase 1 and demonstration of target degradation, pathway inhibition, and preliminary activity in hidradenitis suppurativa (HS) and atopic dermatitis (AD) patients (results published in Nature Medicine), the program has transitioned to Sanofi which is responsible for conducting randomized, placebo-controlled Phase 2 studies in HS and AD that are ongoing.
You will apply your immunology biology and translational medicine experience to identify and solve challenges and drive efficient decision-making for all translational immunology projects, from assay development to clinical translation of immunology pipeline programs. You will also provide input on other I/I programs, as needed.
* Provide Translational Medicine and Immunology leadership to multiple drug discovery programs in Kymera's immunology pipeline, driving translational projects from discovery into early and late clinical development.
* Collaborate with key stakeholders to define clear translational trial endpoints.
* Bring a rigorous and efficient science-first philosophy to enable real-time analysis of clinical trial laboratory data.
* Direct efforts at both Contract Research Organizations and in Kymera's labs, as needed, to support clinical biomarker studies and drive progression within aggressive timelines.
* Enable program success through building external relationships to bring appropriate scientific experts to identify and solve key problems within programs.
* Represent the program team in discussions with management, scientific advisors, and external stakeholders.
* Work with management to ensure progress to goals and flexibly manage priorities in a dynamic scientifically rigorous small company environment.
* Mentor and provide guidance to translational medicine project leads.
What skills and experience you'll bring:
* PhD, MD/PhD in Immunology or related discipline with a minimum of 15 years of relevant experience in preclinical and clinical immunology, including project leadership experience. Training/experience in clinical laboratory medicine preferred.
* Expertise in the subject area of Immunology, with a track record of translating molecular understanding of disease processes into competitive clinical positioning of projects.
* Proven track record of developing and successfully implementing translational immunology, pharmacodynamic, and patient selection assays in Phase 1 and Phase 2 clinical trials.
* Experience in both large and small company environments is preferred.
* Strong communication skills, including track record of publications, presentations, and key contributions to regulatory documents (e.g. briefing documents, IND, NDA).
* Attention to detail and proven success in handling, analyzing, and presenting experimental and translational data to drive decision making.
* Excellent oral and written communication skills with the ability to manage discussions with a variety of audiences ranging from junior team members to Executive Team.
* Demonstrated capability to collaborate with, lead, influence and inspire team members, stakeholders, and peers.
* Enthusiastic, goal-driven, open-minded, creative and self-aware, with excellent communications, strategic and people-leadership skills.
* Willingness to "roll up your sleeves" and engage at the direct hands-on level to ensure that decisions are implemented and driven to results.
Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.
