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Vice President of Antibody Discovery Programs

2 months ago

Watertown, United States Alloy Therapeutics Full time
The Company
We are Alloy Therapeutics-a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of our revenue in innovation and access to innovation. MAY THE BEST DRUG WIN.

Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, Switzerland, and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture.

This is an on-site and full-time position in Waltham, MA. At Alloy, we have an ethos of "Mentorship-By-Apprenticeship" in all of our positions. We strive to have workers in the office when needed to interact organically and face-to-face. Of course, as a lab-based operation, our cells and animals grow 7 days a week, 365 days per year. We respect and value our colleagues for their hard work that requires them to be in the lab every day. We ask our people who have more flexible accommodations, like this position, to appreciate their colleagues who have less flexibility. We are all one team

The Team
Alloy's Antibody Discovery Services (ADS) team is adding a new senior leadership position for a Vice President of Antibody Research Programs based in Waltham, Massachusetts. Our antibody discovery services team seamlessly integrates our proprietary in vivo, in vitro and in silico platforms to collaborate with others to discover and optimize antibody-based therapeutics. In this role, you'll work with a team of 50 colleagues in Waltham supported by a global Alloy team of nearly 100 people across our sites in Cambridge, UK, Basel, Switzerland and Athens, Georgia. At ADS, we employ cutting-edge technologies in molecular biology, protein sciences, B-cell cloning, phage and yeast display, novel antibody formats and analytics to identify and optimize antibody-based therapeutics. You will be a key member of the team overseeing antibody discovery strategies and program execution at the Waltham site with the goal of making medicine together with our external partners.

The Role
As the Vice President of Antibody Research Programs, you will play a pivotal role in shaping and leading strategies for our antibody discovery initiatives. This key leadership position entails driving the discovery of novel antibody-based therapeutics, including monoclonal and bispecific antibodies and T-cell receptor mimetic therapeutics. You will be personally responsible for overseeing dozens of therapeutic discovery programs every year by working collaboratively with a range of large pharma companies, emerging biotech companies and academic collaborators. In this role, you are guaranteed to be making medicine that will be in patients in the near term and, with any luck, will ultimately be approved therapeutics. We take our responsibility to our partners and their patients very seriously and we will ask you and your team to take great care as well.

A crucial aspect of this role involves providing a deep understanding of drug discovery projects to drive effective project strategies in collaboration with our partners. This is a highly scientific position that requires your expertise in antibodies specifically and drug discovery more generally. You will ensure executional excellence by evaluating scientific strategies, reviewing data in real time and making the necessary scientific adjustments to ensure a successful therapeutic discovery campaign. In addition, you will manage teams overseeing the successful completion of project activities, accomplishing shared objectives, and meeting rigorous partner timelines. Additionally, you will spearhead new technological innovation to implement and optimize cutting-edge technologies and to develop new methods, while also improving existing processes to advance therapeutic discovery projects with maximum efficiency. Our goal is always to be the most responsive and attentive discovery service partner in the industry.

Strong communication skills are essential for this role, as you will interact with a diverse group of stakeholders both within and outside the company. This involves providing regular project updates and presentations to internal stakeholders to ensure alignment with project goals and timelines, and addressing any potential issues or concerns promptly. You will also be responsible for partner communication throughout the project life cycles, including drafting research proposals, updating project status and timelines, and presenting final deliveries.

This role will report directly to the Senior Vice President of Antibody Discovery Services in Waltham, MA, with autonomy owning various stakeholders, projects, and tasks in a dynamic start-up environment while keeping up the pace of Alloy. You will have direct, daily contact with our CEO, President of Research, CSO and other C-level executives.

How You'll Drive Impact
  • Drive: Scientific direction and execution of monoclonal, bispecific and TCRm discovery projects.
  • Innovate: Ensure the application of cutting-edge technologies and methodologies in antibody discovery projects.
  • Collaborate: Integrate protein engineering and cutting edge efforts efficiently into product offerings and engage with external collaborators in discovery of biologics.
  • Deliver: Efficient execution of partner projects balancing quality, timelines, and costs, while ensuring successful completion of therapeutic discovery that meet our partners' objectives.
  • Lead: Marshall, inspire, and mentor a cross-functional team of scientists. Lead by example by going the extra mile to ensure we are successful delivering on projects.
  • Communicate: Communicate effectively with key stakeholders externally and internally, fostering productive interactions both upward and downward, and across teams at different sites.
Why We Value You
  • You have a PhD degree in a relevant scientific field (e.g. Biochemistry, Biotechnology, Biology).
  • You have a minimum of 8-10 years of experience and a strong understanding of antibody and early drug discovery and development.
  • You have a proven track record of success in leading and managing biologics discovery teams.
  • You have broad and deep experience with antibody discovery and engineering.
  • You have a strong background in the design and optimization of antibody-based therapeutics.
  • You have a proven track record of successful execution and delivery of projects within scope, budget, and timeline.
  • You have demonstrated the ability to work in a fast-paced, dynamic environment and adapt to changing priorities and deadlines.
  • You have excellent communication skills, both written and verbal, with the ability to effectively communicate with stakeholders at all levels.
  • You have excellent leadership and team management skills, with the ability to motivate and mentor team members.
Desired Multipliers
  • Experience working directly with external companies on scientific service offerings.
  • Ability to work across various US and international time zones.
  • Accommodate occasional travel as needed (10%).
Taking Care of Our People
We support the individuality of what people need to do outside of work to empower them to do their best at work. While you focus on making better medicine together, we focus on programs and benefits that support a diverse and growing team. Whether you're single, in a growing family, or nearing retirement, Alloy offers a variety of comprehensive and competitive benefits starting from day one.
Compensation
  • Competitive base and equity compensation commensurate with level of experience and independence
  • 401(k) company match
Health & Family
  • Generous personal and family medical, dental and vision benefits with 100% of premiums and deductibles covered
  • Company-paid disability (STD, LTD) and life insurance
  • Paid parental leave
  • Family planning support up to $45,000 (e.g., IVF/PGT, adoption, surrogacy, egg retrieval)
Unique Perks
  • Unlimited PTO (paid time off) and flexible schedules
  • Annual stipend for continuing education with commitment to your career through individualized professional development plan
  • Wellness and Extensive Employee Assistance Program (EAP) including resources for mental wellness

Diversity, Equity, and Inclusion
Here at Alloy, we democratize capabilities for discovering and developing therapeutic biologics. So, being diverse and inclusive isn't just something we strive for, it is who we are, and part of what we do each and every single day. We want to ensure that as an employee, you feel Alloy is a place where, no matter who you are, you feel safe, included, and that you have the opportunity to bring your unique self to work.

Alloy Therapeutics is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, sexual orientation, gender identity, veteran status, disability, or other legally protected status. If you are unable to submit an application because of incompatible assistive technology or a disability, please contact us at [email protected]. We will make every effort to respond to your request for disability assistance as soon as possible.