Associate Principal Data Scientist, Single-Cell Genomics and AI

1 month ago


Cambridge, Massachusetts, United States Merck Full time

Job Description

Our Artificial Intelligence and Machine Learning (AI/ML) capabilities are vital catalysts for our mission to invent new medicines that save and enhance lives. The Data, AI, and Genome Sciences (DAGS) function at our organization adopts an AI/ML-first approach to enhance target and biomarker discovery by driving the understanding of complex disease mechanisms. As Associate Principal Data Scientist, you will leverage your quantitative, computational and AI/ML skills in single-cell Omics to drive the development of state-of-the-art multi-modal AI/ML models to discovery disease biology. You will collaborate with Computational Biologists, Data Scientists, Software Engineers, and AI/ML Engineers as part of a cross-functional team dedicated to identifying therapeutic targets.

Primary Responsibilities:

  • Collaborate with cross-functional team to identify research questions, data requirements, and develop appropriate machine learning solutions.
  • Develop and implement cutting-edge AI/ML and computational approaches to integrate, analyze, and model single-cell omics data including spatial transcriptomics to understand disease biology for target discovery.
  • Stay up to date with the latest advancements in single-cell omics technologies, multi-modal data integration and novel AI/ML modeling approaches and apply relevant advancements to improve existing methodologies and models.
  • Publish research findings in relevant conferences and journals, and actively contribute to the scientific community through knowledge sharing and collaborations.

Required Experience and Skills:

  • PhD in a relevant field such as mathematics, physics, computational biology, systems biology, or a related discipline, with 5+ years of experience in genomic technologies, single-cell genomics analysis, computational approaches, and AI/ML. Can consider MS and 8+ years of experience or BS and 12+ years of experience.
  • Strong understanding of single-cell genomics data, profiling techniques, analytic workflows and pipelines, algorithms, statistical approaches, and relevant tools.
  • Strong expertise and experience in modern AI/ML approaches, probabilistic modeling, causal inference, and advanced, cutting-edge computational approaches and technologies.
  • Proficiency in programming languages such as Python, and experience with deep learning frameworks and libraries like PyTorch.
  • Excellent communication skills and ability to work collaboratively in a multi-disciplinary team.

Preferred experience:

  • Relevant publications in scientific journals and experience contributing to research communities.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

#EligibleforERP

Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders). Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated. Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

EEOC Know Your Rights

EEOC GINA Supplement​

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

Learn more about your rights, including under California, Colorado and other US State Acts

U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, generally Tuesday, Wednesday and either Monday or Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Regular

Relocation:

Domestic/International

VISA Sponsorship:

Yes

Travel Requirements:

10%

Flexible Work Arrangements:

Hybrid

Shift:

Not Indicated

Valid Driving License:

No

Hazardous Material(s):

n/a

Required Skills:

Business Intelligence (BI), Database Design, Data Engineering, Data Modeling, Data Science, Data Visualization, Machine Learning, Project Management, Software Development, Stakeholder Relationship Management

Preferred Skills:

Job Posting End Date:

08/16/2024

*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Job Posting End Date:08/16/2024

A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID:R304692



  • Cambridge, Massachusetts, United States Sana Biotechnology Full time

    About the role Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Senior Scientist, you will report to the Senior Genomics Lead, and work under the broader...


  • Cambridge, Massachusetts, United States GC Therapeutics Full time

    Position: Scientist / Senior Scientist – Computational BiologyCompany OverviewGC Therapeutics is a pioneering company focused on genome-wide cell landscape exploration, utilizing an integrated synthetic biology and AI-driven platform for cell programming. Our proprietary technology platform, TFomeTM, developed in the lab of Professor George Church, a...


  • Cambridge, Massachusetts, United States Novartis Farmacéutica Full time

    Position Overview:As a Lead Scientist specializing in Clinical Genetics and Genomics, you will play a pivotal role in our Biomarker Development team. This position emphasizes hands-on experience in crafting and executing genetic and genomic assays, including both targeted and next-generation sequencing (NGS) technologies.Your analytical skills will be...


  • Cambridge, Massachusetts, United States Novartis Farmacutica Full time

    Position Title: Lead Scientist, Clinical Genetics and GenomicsLocation: USARole Overview: In this pivotal laboratory-based role within Biomarker Development, you will utilize your extensive expertise in the creation and execution of genetic and genomic assays, including both targeted and next-generation sequencing (NGS) technologies. Your data analysis...


  • Cambridge, Massachusetts, United States Merck Full time

    Job DescriptionThe Data, AI, and Genome Sciences department is looking for a passionate and talented computational biologist with expertise in the analysis of complex multi-readout and multi-scale genomics assays and imaging screens to join our Translational Genome Analytics research team.In this role, you will be at the cutting-edge of discovery research,...

  • Associate Scientist

    2 months ago


    Cambridge, Massachusetts, United States Intellia Therapeutics Full time

    Why Join Intellia?Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to...


  • Cambridge, Massachusetts, United States Intellia Therapeutics Full time

    Why Join Intellia?Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to...


  • Cambridge, Massachusetts, United States Vesalius Therapeutics Full time

    Bioinformatics Scientist Vesalius Therapeutics is on the lookout for a dedicated and innovative Bioinformatics Scientist eager to utilize single-cell genomic data to uncover the biological underpinnings of health and disease. The selected candidate will engage in the statistical design and evaluation of genomic studies (e.g., single-cell RNA sequencing,...

  • Research Scientist

    1 week ago


    Cambridge, Massachusetts, United States GC Therapeutics Full time

    Become a part of our visionary teamAt GC Therapeutics, we are at the forefront of genome-wide cellular research. Our innovative methodology merges synthetic biology with artificial intelligence to enhance cell programming. Our state-of-the-art technology platform, TFomeTM, facilitates the creation of revolutionary cell therapies that prioritize quality and...


  • Cambridge, Massachusetts, United States Relay Therapeutics Full time

    The Opportunity:We are seeking an innovative, collaborative, and motivated cell/molecular biologist to join our growing team. At Relay Therapeutics, we apply cutting edge technology towards the discovery, characterization, and optimization of small molecule therapeutics towards targets representing high, unmet medical needs. The successful candidate will...


  • Cambridge, Massachusetts, United States GC Therapeutics Full time

    In Vivo Research ScientistCompany OverviewGC Therapeutics is pioneering the exploration of genome-wide cell landscapes through an innovative synthetic biology and AI-driven platform for cell programming. Our proprietary pluripotent stem cell differentiation technology, TFomeTM, was developed in collaboration with Professor George Church's lab, a leader in...

  • Associate Scientist

    2 months ago


    Cambridge, Massachusetts, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...


  • Cambridge, Massachusetts, United States Harvard University Full time

    Job DescriptionWe are seeking a highly motivated postdoctoral researcher (or research associate) to join our team at Harvard University's Department of Organismic and Evolutionary Biology. The successful candidate will have expertise in comparative genomics and sequence analysis, with a strong interest in bioinformatics programming, data mining, and...


  • Cambridge, Massachusetts, United States Proclinical Full time

    Principal Associate Scientist for Analytical Development - Contract - Cambridge, MA Proclinical is actively seeking a Principal Associate Scientist. This is a temporary contract position based in Cambridge, Massachusetts, MA. Primary Responsibilities:This role is primarily focused on the initial characterization testing, annual re-qualification, and trending...


  • Cambridge, Massachusetts, United States MIT Full time

    **Job Summary**We are seeking a highly skilled Technical Associate II to join our team at the Koch Institute for Integrative Cancer Research (KI)-High Throughput Sciences (HTS). As a key member of our team, you will play a foundational role at the interface of basic science and automation to accelerate discoveries and shape the future of oncology.**Key...

  • Senior Scientist

    4 days ago


    Cambridge, Massachusetts, United States GC Therapeutics Full time

    Job Title: Senior Scientist - Assay DevelopmentGC Therapeutics is a pioneering genome-wide cell landscape exploration company that leverages an integrated synthetic biology and AI-driven platform for cell programming. Our patent-pending and proprietary pluripotent stem cell differentiation technology platform, TFomeTM, was developed in Professor George...


  • Cambridge, Massachusetts, United States GC Therapeutics Full time

    Position Title: In Vivo Research ScientistCompany OverviewGC Therapeutics stands at the forefront of genome-wide cellular exploration, leveraging an innovative synthetic biology and AI-driven platform for cellular programming. Our proprietary pluripotent stem cell differentiation technology, TFomeTM, was pioneered in the lab of Professor George Church, a...


  • Cambridge, Massachusetts, United States Merk Full time

    Job Requirements This posting has been created to pipeline talent for prospective roles that we anticipate will be needed in the future for our organization. By applying to this Pipeline Advertisement you will be submitting your interest to be contacted for future roles similar to what is described in the Pipeline Advertisement.The Senior AI/ML Data...


  • Cambridge, Massachusetts, United States GlaxoSmithKline Full time

    A career in Boston - main video - YouTube At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. We believe the Greater Boston area is an important hub...


  • Cambridge, Massachusetts, United States Intellia Therapeutics Full time

    Why Join Intellia?Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to...