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Senior Scientist, Genomics in Stem Cell Sciences Group

3 months ago


Cambridge, Massachusetts, United States Sana Biotechnology Full time

About the role

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Senior Scientist, you will report to the Senior Genomics Lead, and work under the broader direction of the Head of Stem Cell Sciences. Your daily responsibilities include the collection of in vitro and in vivo samples, and library preparation for genomic assays, including single cell genomics, CUT&TAG, CUT&RUN, WGS, and Amplicon-sequencing. You will also work closely with other wet-lab scientists within the team to coordinate and process samples, managing data log and annotations, and experimental design.

What you'll do

Library preparation of epigenetics and DNA assays (CUT&TAG, CUT&RUN, WGS, WES, Amplicon-sequencing)
Library preparation of assays related to single cells (scRNA-seq, scATAC-seq, scMultiome-seq, CITE-seq)
Assure the quality, integrity, and documentation of all data collection including compliance with all relevant lab safety and biosafety regulations
Capture and analyze in vitro cell samples as well as in vivo samples

What we're looking for
Advanced degree in cell biology or molecular biology with 5 years of experience
Experience in flow cytometry, including sorting of cells based on fluorescent labels
Experience with library preparation for single cell genomic assays, especially the 10x Genomics Platform
Experience with CUT&TAG and CUT&RUN library preparation
Proficiency in flow cytometry analysis and quantification (ie FlowJo)
Experience in cell isolation from tissues

What will separate you from the crowd
Experience with data management and recording of scientific protocols using benchling
Organization and project management skills

What you should know
The base pay range for this position at commencement of employment is expected to be between $145,000 and $175,000/year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience
How we work together for patients
Lead from every seat – we seek to understand, act with honesty, and engage in the crucial conversations
Thrive as a team – we hire amazing people, are intensely curious, and cultivate inclusion and personal connectivity
Make it happen – we value vigorous debate, alignment around our decisions, and resilient execution

Get to know us

At Sana, we believe that a diverse workforce strengthens us as a company and helps us to achieve our mission to meaningfully change the outcome of many human diseases. This belief is a pillar of our business and is critical to our success. Our goal is that Sana is the place for talented people to bring their authentic selves to work, to have a great career and to deeply, positively impact patients.

Core to our values, we believe there is nothing more important than the health and wellness of you and your family. For benefit eligible employees, we cover 100% of the cost for employee health coverage and offer generous time-off (various paid time off benefits, such as holidays, vacation, sick time, and parental leave), short- and long-term disability, employer paid basic life insurance, additional voluntary life insurance protection, financial wellness programs including financial planning resources, a 401(k) Plan with an immediately vested employer match, Tuition Reimbursement and Student Loan Repayment, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually. For more details on our benefits, visit Sana's Benefits Portal.

We are committed to providing a workplace free of discrimination and harassment based on race, color, religion, age, gender, national origin, ancestry, physical or mental or sensory disability (including the use of a trained guide dog or service animal by a person with a disability), genetic information, actual or perceived HIV or Hepatitis C infection, medical condition (cancer or a record or history of cancer and genetic characteristics), marital status, sexual orientation, sexual preference, pregnancy (including childbirth and related medical conditions), disability, veteran status, political ideology, social class (including caste/caste identity), taking or requesting statutorily protected leave, status as a victim of domestic violence, sexual assault or stalking, or any other basis prohibited by applicable law.

To perform this job successfully, you must be able to perform each job responsibility satisfactorily. The job description listed above is representative of the knowledge, skills, and/or abilities required for this position. Reasonable accommodations may be made to enable individuals with disabilities to perform the functions described above.