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Associate Scientist, Analytical Development
2 months ago
About Allogene:
Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR TTM) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of "off-the-shelf" CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. For more information, please visit , and follow @AllogeneTx on X (formerly Twitter) and LinkedIn.
About the role:
We are seeking a highly motivated Associate Scientist to join our Analytical Development group and contribute to the commercialization of allogenic CAR T therapies. The Associate Scientist will play a key role in CAR T cell therapy related analytical assay development and execution of drug product release and characterization assay.
The individual will work closely with peers in assay development, assay qualification, execution of the release and characterization assays, comprehensive risk assessments, and data synthesis that allows for the subsequent analytical assay tech transfer. This role will be based at the headquarters in South San Francisco, CA.
Responsibilities include, but are not limited to:
- Perform analytical assays such as PCR, ELISAs, cell-based potency assays and flow cytometry, etc., for cell therapy products. Maintain mammalian cell culture for testing.
- Maintain, calibrate, and operate analytical instruments. Maintain sample inventories.
- Ensure high-quality, timely documentation in electronic laboratory notebooks (ELN) with great attention to details.
- Coherently summarize and communicate experiments and findings and present study results at team meetings to internal stakeholders
- Assist in analytical method optimization, development, and qualification in support of product and process development and product characterization.
- Demonstrate strong accountability, organizational and interpersonal skills, and apply sound scientific and technical experience.
- Work collaboratively with cross-functional teams to meet deadline-dependent milestones and advance the development of Allogene's CAR T programs.
- Other duties as assigned.
Position Requirements & Experience:
- Bachelor's Degree with 0-3 years of relevant cell biology, immunology or biochemistry experience.
- Ability to work independently and as part of a team.
- Experience with cell culture, cell banking, and aseptic technique is required.
- Prior working knowledge of nucleic acid isolation, quantification, and PCR is preferred.
- Prior working knowledge in ELISA, FACS a plus.
- Experience with data analysis tools such as Prism, FlowJo and Microsoft Excel a plus.
- Working knowledge of quality control and assay qualification is a plus.
- Self-motivated, organized and detail-orientated, with a positive "can-do" attitude towards assigned tasks is expected.
- Candidates must be authorized to work in the U.S.
We offer a chance to work with talented people in a collaborative environment. Actual pay will be determined based on experience, qualifications, geographic location, business needs, and other job-related factors permitted by law.
As an equal opportunity employer, Allogene is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment and internships designed to create a stronger and better Allogene that is focused on developing life-changing products for patients.
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