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Lead Analytical Chemist
2 months ago
We are seeking a highly skilled Senior Analytical Scientist to join our team at Addison Group. As a key member of our analytical team, you will be responsible for designing and executing experiments to fully characterize oligonucleotide drug substances and drug product materials.
Key Responsibilities- Experiment Design and Execution: Design and execute experiments to fully characterize oligonucleotide drug substances and drug product materials.
- Analytical Characterization: Demonstrate proficiency with analytical characterization techniques, including mass spectrometry, liquid chromatography, UV/Fluorescence, and electrophoresis.
- Scientific Innovation: Ability to independently conceive, develop, execute, and implement novel/advanced scientific techniques.
- Reporting and Communication: Report at project team meetings, write analytical development reports, and provide recommendations to management.
- Team Leadership: Manage and support junior team members.
- Collaboration: Collaborate with internal and external manufacturing partners to develop robust analytical methods.
- Interdisciplinary Collaboration: Participate in multidisciplinary teams, including Biology and Chemistry, to present results and recommendations to management.
- Quality Assurance: Ensure the quality of each delivered entity.
- Documentation: Maintain lab notebooks, report data with analysis of results in presentations and/or written reports to the scientific team.
- Education and Experience: The level of this position will depend on education and experience qualifications:
- Scientist - PhD: PhD in analytical, organic chemistry or a related discipline with minimum of 4 years of direct experience in oligonucleotide analysis and formulation.
- Scientist - PhD: PhD in analytical, organic chemistry or a related discipline with minimum of 1 year of direct experience in oligonucleotide analysis and formulation.
- Principal Research Associate - MS: MS in analytical, organic chemistry or a related discipline with minimum of 8 years of direct experience in oligonucleotide analysis and formulation.
- Industry Experience: Experience in the biotechnology and/or pharmaceutical industry is preferred, with direct experience with (semi)automated instruments.
- Method Development Skills: Strong method development skills, including experience with liquid chromatography, capillary electrophoresis, and mass spectrometry techniques.
- Software Proficiency: Proficiency with Chromeleon, Xcalibur, and Biopharma Finder is preferred.
- Project Management: Experience with managing project teams in a biotechnology organization is preferred.
- Publication History: A history of authoring publications and/or study reports.
- Teamwork: A deep commitment to working as part of teams to deliver breakthrough medicines.
- Communication and Organization: Excellent communication, organization, and time management skills and ability to work both independently and collaboratively.
