Associate, Bioanalytical Operations

What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.

Our Endosomal Escape Vehicle (EEVTM)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.

Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45 and 50 skipping amenable. We have also partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.

We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.

The Perfect Addition to Our Team

As a member of the Bioanalytical group in the Product Development Team, you are versatile, self-motivated, timeline- and process-oriented, and look forward to rolling up your sleeves and diving into details and overcoming obstacles. You will be responsible for operational oversight within our bioanalytical team. You will successfully establish an infrastructure within the bioanalytical team to ensure smooth daily operations in lab activities, data management, internal/external communications, and finance planning/tracking. To accomplish these aims you will work in close collaboration with bioanalytical team members, as well as cross-functional teams including program management, operations, and finance. You will be actively engaged in all aspects of the bioanalytical team operations from establishing and monitoring reagent inventory to CAPEX management. Additionally, you will be a key contributor to team adherence to timelines as well as the various deliverables within the bioanalytical team and in collaboration with CROs.

You also enjoy a fast-paced environment and juggling competing priorities. You have excellent verbal and written communication skills, you follow up and follow through, bringing solutions to problems efficiently. You work successfully in a team environment with strong interpersonal skills to effectively build working relationships inside and outside the company.

The Opportunity

Work within the Bioanalytical Team to enable the full spectrum of EEV-conjugated modalities development from early discovery candidate selection through late-stage process development.

Responsibilities

• Plans and coordinates required sample management operational activities including collection, delivery, and analysis of biological samples.
• Adhere to current regulatory guidelines and compliance for sample storage.
• Act as a key point of contact for data management within the bioanalytical team, using platforms such as ELNs and LIMS.
• Implement a robust practice of collecting, organizing, protecting, and storing data within the team.
• Monitor and maintain project needs and necessary bioanalytical lab supplies, such as solvents, tubes, 96-well plates, etc. by routinely performing stock inventory, placing orders, and re-stocking.
• Communicate and work effectively and cooperatively with team members to ensure an integrated workflow from sample receipt to data/report delivery.
• Provide financial management and budget oversight for bioanalytical projects; communicate externally with vendors to provide project-specific financial updates.
• Facilitate meetings and plan and coordinate events, including supporting agendas and logistics, etc.
• Act as a key point of contact and resource for internal team members and external stakeholders regarding sample management, bioanalytical laboratory facilities, and bioanalytical vendors.
• May assist in writing reports, protocols, manuals, and other documentation as needed; may perform QC review of data/documentation as needed.
• Develop tools and processes that optimize project efficiency and effectiveness.

The Necessities

At Entrada, our passion for science, our devotion to patients and our values drives our behavior:

• Humanity - We genuinely care about patients and about one another.
• Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
• Creativity - We are creative problem solvers.
• Collaboration - We are more than the sum of our parts.
• Curiosity - We have a growth mindset and push conventional thought and theory.

To thrive on our team, you will need to come with:

• BS in a scientifically relevant field with 5 + years of industry experience in related roles.
• In-depth knowledge of Lab Operations procedures and applicable laboratory testing regulations.
• Working knowledge of quality assurance and quality control principles and in-depth knowledge of company-specific program requirements.
• Strong interpersonal, communication, organizational, financial, and time management skills.
• Ability to prioritize tasks, work under time constraints, and meet deadlines.
• Ability to assess and prioritize multiple tasks, projects, and demands.
• Excellent computer skills, including proficiency in Microsoft Office suite and web-based applications.
• Ability to establish and maintain effective working relationships with team members, managers, and those in cross-functional teams. #LI-JF1

By becoming a team member here at Entrada, you'll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.

Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.

Third Party Staffing Agencies

Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.

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