Current jobs related to Senior Scientist II, Bioanalytical - Boston, Massachusetts - Entrada Therapeutics
-
Bioanalytical Research Scientist
3 days ago
Boston, Massachusetts, United States Strand Therapeutics Full timeJob SummaryStrand Therapeutics is seeking a highly motivated and enthusiastic Co-op, Bioanalytical to join our Nonclinical/Translational Development team. As a member of our team, you will have the opportunity to work in a matrix-based environment and contribute to the future strategy of the company.Key ResponsibilitiesDevelop, optimize, qualify, and execute...
-
Boston, Massachusetts, United States PepGen Full timeJob OverviewPepGen is seeking a highly skilled and innovative Senior Research Scientist to join the Preclinical Research and Development group in Boston, Massachusetts. The successful candidate will be primarily responsible for the key aspects of the research and development, including pharmacology, of PepGen's Enhanced Delivery Oligonucleotide (EDO)...
-
Boston, Massachusetts, United States PepGen Full timeJob OpportunityPepGen is seeking a highly skilled and innovative Principal Scientist to join our Preclinical Research and Development team in Boston, Massachusetts. As a key member of our team, you will be responsible for leading the development, optimization, and execution of in vitro and in vivo nonclinical pharmacology studies.Key...
-
Research Scientist II
1 week ago
Boston, Massachusetts, United States Mass General Brigham Full timeJob Title: Research Lab Tech IIJob Summary:The Research Lab Tech II position involves conducting research and administrative tasks in a laboratory setting. Under the supervision of the Principal Investigator, the Research Lab Tech II will conduct independent and collaborative research involving molecular biology and microbiology techniques.Key...
-
Research Scientist II
1 month ago
Boston, Massachusetts, United States Mass General Brigham Full timeJob Title: Research Lab Tech IIJob Summary:The Research Lab Tech II position involves conducting research and administrative tasks in a laboratory setting. Under the supervision of the Principal Investigator, the Research Lab Tech II will conduct independent and collaborative research involving molecular biology and microbiology techniques.Key...
-
Senior Data Scientist
1 week ago
Boston, Massachusetts, United States Resource Informatics Group Full timeJob Title: Senior Data ScientistJob Summary:Resource Informatics Group is seeking a highly skilled Senior Data Scientist to join our team. As a Senior Data Scientist, you will be responsible for developing and implementing data-driven solutions to drive business growth and improve operational efficiency.Key Responsibilities:Design and develop predictive...
-
Senior Scientist Chair
7 days ago
Boston, Massachusetts, United States Aza Full timeJob Title: Senior Scientist ChairWe are seeking a highly accomplished scientific researcher to lead our Krause Marine Mammal Conservation Program as the Senior Scientist Chair. This full-time position comes with a range of benefits and a typical schedule of Monday - Friday from 9a - 5p EST.The Senior Scientist Chair will be responsible for leading the...
-
Senior Data Scientist
3 days ago
Boston, Massachusetts, United States Resource Informatics Group Full timeJob Title: Senior Data ScientistJob Summary:Resource Informatics Group is seeking a highly skilled Senior Data Scientist to join our team. As a Senior Data Scientist, you will be responsible for developing and implementing data-driven solutions to drive business growth and improve operational efficiency.Key Responsibilities:Design and develop advanced data...
-
Senior Data Scientist
1 week ago
Boston, Massachusetts, United States Motion Recruitment Full timeA leading pharmaceutical company is seeking a remote Senior Data Scientist to develop machine learning models for a customer-facing application.This company creates iconic brands in the medical beauty aesthetics sector.In this role, you will lead a team of data scientists and engineers to build and deploy machine learning models at scale.You will bring 7+...
-
Boston, Massachusetts, United States Tempus Full timeWe are seeking a highly motivated and solutions-oriented Data Scientist II to join our Real World Evidence (RWE) group within the Pharma R&D team at Tempus.The ideal candidate will have experience working with clinical and research data pipelines, and/or performing biostatistical, epidemiological, or real-world data analytics on observational healthcare...
-
Boston, Massachusetts, United States CRISPR Therapeutics Full timeJob OverviewCRISPR Therapeutics is a pioneering biotech company at the forefront of gene editing and therapeutics. We are seeking a highly skilled Senior/Principal Scientist to join our team and contribute to the development of next-generation mRNA technology and therapeutics.Key ResponsibilitiesDrive the discovery of innovative RNA/LNP delivery technologies...
-
Senior Formulations Scientist
1 week ago
Boston, Massachusetts, United States Elektrofi Inc Full timeJob Title: Senior Formulations ScientistWe are seeking a highly skilled Senior Formulations Scientist to join our team at Elektrofi Inc. As a key member of our formulation development team, you will play a crucial role in the development of our ultra-high concentration microparticle suspension products.Key Responsibilities:Lead the development of novel,...
-
Senior Data Scientist
7 days ago
Boston, Massachusetts, United States Motion Recruitment Full timeBoston, MARemoteFull Time$190k - $200kA leading US pharmaceutical company is seeking a remote Senior Data Scientist to build out the backend machine learning of a customer-facing application.This company creates iconic brands in the medical beauty aesthetics sector.In this role, you will lead and manage a small team of data scientists and build AI and ML...
-
Senior Research Scientist
3 days ago
Boston, Massachusetts, United States Extreme Event Solutions Full timeJob Title: Senior ScientistAt Extreme Event Solutions, we're seeking a highly skilled Senior Scientist to join our Research and Modeling department. As a key member of our wildfire modeling team, you'll work closely with stakeholders to develop, optimize, and deploy advanced computational models that simulate fire ignition, spread, and penetration into the...
-
Senior Scientist
6 days ago
Boston, Massachusetts, United States Takeda Full timeAbout the RoleAt Takeda, we are a forward-thinking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. As a Senior Scientist - Analytical Development, you will provide and drive theoretical/conceptual input to the design, development, and execution of research assignments for a specific project or projects...
-
Senior Research Scientist
1 week ago
Boston, Massachusetts, United States Boston Childrens Hospital Full timeJob SummaryThe Boston Children's Hospital is seeking a highly skilled and experienced Staff Scientist/Research Lead to join their Research and Evaluation team. This full-time, hybrid position is based in Boston, MA, and offers a competitive salary and benefits package.As a Staff Scientist/Research Lead, you will be responsible for leading daily operations of...
-
Research Scientist II
1 week ago
Boston, Massachusetts, United States Brigham & Women's Hospital(BWH) Full timeJob SummaryWe are seeking a highly motivated and detail-oriented Research Scientist II to join our team at Brigham & Women's Hospital(BWH). The successful candidate will have a strong background in biological research and experience in molecular biology, genomic, and cellular biology.Key ResponsibilitiesIndependently perform routine and non-routine...
-
Senior Data Scientist
1 week ago
Boston, Massachusetts, United States TechStarsGroup Full timeJob OverviewOur client, a venture-backed company, has developed a cutting-edge system to enhance the analysis and understanding of electronic medical records (EMRs). This system streamlines the review process by automating manual tasks and ensuring data security within the system. It intelligently screens and matches patient data to clinical criteria,...
-
Senior Data Scientist
3 weeks ago
Boston, Massachusetts, United States TechStarsGroup Full time{"h1": "Senior Data Scientist", "p": "At TechStarsGroup, we are seeking a highly skilled Senior Data Scientist to join our Clinical Data Science team. As a key member of our team, you will play a pivotal role in providing programming, advanced statistical, and machine learning expertise to support research initiatives focused on digital biomarkers and...
-
Senior Scientist, Computational Biology Expert
2 weeks ago
Boston, Massachusetts, United States Takeda Pharmaceutical Full timeAbout the Role:Takeda Pharmaceutical is a world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. We are seeking a Senior Scientist to join our multi-disciplinary Early Clinical Development team.The successful candidate will support clinical-stage portfolios, including biomarker discovery and biomarker-driven...
Senior Scientist II, Bioanalytical
4 months ago
What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible.
Our Endosomal Escape Vehicle (EEVTM)-therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues, resulting in an improved therapeutic index. Through this proprietary, versatile and modular approach, Entrada is advancing a robust development portfolio of RNA-, antibody- and enzyme-based programs for the potential treatment of neuromuscular, ocular, metabolic and immunological diseases, among others.
Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne who are exon 44, 45 and 50 skipping amenable. We have also partnered to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1.
We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.
The Perfect Addition to Our Team
As a member of the Bioanalytical group in the Product Development Team, you are versatile, self-motivated, timeline- and process-oriented, and look forward to rolling up your sleeves and diving into details, and overcoming obstacles. You will be responsible for mentoring members of the team and be accountable for their day-to-day operations and personal career development. You will successfully lead and coordinate bioanalytical support functions across various modalities, including oligonucleotide and biologics modalities, to perform both qualitative and quantitative bioanalysis in complex biological matrices. To accomplish these aims you will actively explore, investigate, and implement innovative technologies to meet program timelines. You will lead internal efforts to provide timely bioanalytical support for discovery projects and pre-IND clinical candidate studies. Additionally, you will be a key contributor to documents supporting regulatory filings and will have the opportunity to contribute to scientific publications.
You also enjoy a fast-paced environment and juggling competing priorities. You have excellent verbal and written communication skills, you follow up and follow through, bringing solutions to problems efficiently. You work successfully in a team environment with strong interpersonal skills to effectively build working relationships inside and outside the company.
The Opportunity
Work within the Bioanalytical Team to enable the full spectrum of EEV-conjugated modalities development from early discovery candidate selection through late-stage process development.
Responsibilities
Perform both qualitative and quantitative bioanalysis in various biological matrices (plasma, CSF, urine, and tissues, etc.) across different species. Generate high-quality data and reports in a timely manner to meet project deliverables.
Oversee bioanalytical deliverables supporting discovery project activities, candidate enabling studies, and clinical candidate IND enabling studies; provide scientific guidance and technical support on method development, qualification, and sample analysis in-house as well as at CROs.
Support the implementation of new and upcoming technologies/platforms both within and outside the field of expertise to meet challenging program needs.
Mentor and train team members and colleagues on scientific concepts and technical details regarding various bioanalytical approaches.
Lead troubleshooting efforts for bioanalytical assays; Proactively identify and solve technical challenges/bottlenecks to maintain/improve assay robustness and efficiency.
Implement processes to ensure timelines are met with data integrity; communicate and interface with stakeholders including discovery, preclinical, CMC, and external CROs to define and deliver strategies in a flexible manner to support project timelines across multiple programs.
Interpret and present bioanalytical data internally as well as in cross-functional team meetings; serve as an SME on behalf of the bioanalytical team for technical, strategic, and prioritization discussions to advance program objectives.
The Necessities
At Entrada, our passion for science, our devotion to patients and our values drives our behavior:
Humanity - We genuinely care about patients and about one another.
Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
Creativity - We are creative problem solvers.
Collaboration - We are more than the sum of our parts.
Curiosity - We have a growth mindset and push conventional thought and theory.
To thrive on our team, you will need to come with:
Demonstrated leadership acumen and strong project management/organizational skills; Proven track record of fostering a collaborative work environment.
Subject matter expert with extensive hands-on experience with developing, qualifying, implementing, and troubleshooting LC-MS/MS and ligand binding-based assays to support a variety of therapeutic modalities including oligonucleotides, biologics, and peptides.
Ability to work independently in a fast-paced, competing priority environment, as well as in a cross-collaborative team setting. Excellent communication skills (oral and written) and a track record of cross-disciplinary collaboration are essential.
Knowledge/experience of pharmacokinetics, drug metabolism, immunogenicity, and biomarker studies are highly desirable.
Experience with ligand binding assays such as ELISA and MSD is preferred.
Knowledge and experience with assay development, transfer, qualification, and validation to external CROs in a GLP/GxP environment is considered a plus.
The Perks
By becoming a team member here at Entrada, you'll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, paternity leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. Our location in the vibrant and growing Seaport District is close to all the best that the city of Boston has to offer.
Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.
Third Party Staffing Agencies
Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.
Privacy Statement
Entrada Therapeutics, Inc. (the "Entrada," "we," "us," or "our") respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information. Please reference our privacy statement here to understand how and when your data is being used.
