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Scientist, DMPK

4 months ago


Cambridge, United States Biogen Full time
Job Description

About This Role

Biogen is seeking a highly motivated scientist with excellent knowledge and experience in LC–MS/MS bioanalysis to join the Drug Metabolism and Pharmacokinetics (DMPK) department. The candidate will be responsible for bioanalytical support of discovery and development programs, including small molecule compounds and oligonucleotides. Experience in regulated bioanalysis and GLP studies is preferred. The candidate should be able to effectively manage and prioritize multiple projects to ensure timely support of the projects. Excellent communication and interpersonal skills are required, along with scientific thinking and problem–solving skills.

What You'll Do

Develop new bioanalytical methods for quantification of small molecule compounds and oligonucleotides (ASO, siRNA etc.) in biological matrices.

Analyze biological samples (plasma, CSF, tissue etc.) and timely deliver high quality bioanalytical data to support non–clinical and possible clinical studies.

Oversee non–GLP and GLP bioanalytical activities at CROs. Provide scientific guidance on method transfer/development, qualification/validation, and sample analysis at CROs.

Write and review study protocols and bioanalytical reports that are suitable for inclusion in registration dossiers.

Manage multiple projects within timelines according to high scientific and ethical standards.

Evaluate and implement new bioanalytical technologies for solving DMPK challenges or project needs.

Publish scientific papers and present at external scientific meetings.

Who You Are

You love bioanalysis and are passionate about applying bioanalysis to impact drug discovery and development. You love learning new technological skills and working through collaboration.