Mass Spectrometry Research Scientist

2 weeks ago


South San Francisco, California, United States Vicinitas Therapeutics Full time
Position Overview

Vicinitas Therapeutics is a pioneering biotechnology firm dedicated to the development of targeted protein stabilizers, specifically Deubiquitinase Targeting Chimeras (DUBTACs). Our mission is to leverage this innovative technology to address significant challenges in human health by creating next-generation therapies for previously untreatable disease-causing proteins.

Our Chemical Biology team plays a crucial role in the identification and advancement of DUBTACs through the implementation of state-of-the-art mass spectrometry (MS) methodologies. We are currently seeking a Mass Spectrometry Scientist to manage existing MS platforms and innovate new methodologies to facilitate the identification and validation of DUB recruiters and DUBTACs. The ideal candidate will be a collaborative, inquisitive, and adaptable team member who thrives on problem-solving and working alongside colleagues to achieve our research goals.

Key Responsibilities

  • Design and conduct cell-based screening experiments for proteomics studies.
  • Plan and execute mass spectrometry experiments aimed at elucidating the mechanism of action (MOA) of DUBTACs.
  • Mentor junior scientists within the Chemical Biology team, guiding them in the conceptualization and execution of mass spectrometry experiments.
  • Collaborate with teams in data analysis, protein sciences, and medicinal chemistry to ensure alignment with corporate objectives.

Qualifications

  • PhD in Biochemistry, Analytical Chemistry, Chemistry, or a related discipline.
  • 2-8 years of experience with high-resolution mass spectrometry instruments and techniques in proteomics.
  • Proficient in operating, maintaining, and troubleshooting mass spectrometry equipment, with a preference for experience with ThermoFisher or Bruker systems.
  • Demonstrated expertise in utilizing various software for mass spectrometry data analysis, with experience in developing automated data processing pipelines being advantageous.
  • Skilled in creating custom methods for sample preparation and mass spectrometry analysis to meet project objectives.
  • Strong communicator who exemplifies leadership and adapts to evolving conditions to consistently achieve scientific goals.

Compensation and Benefits

Expected Salary Range: Scientist I $120,000-$130,000 / Scientist II $130,000-$145,000. (Compensation will be commensurate with experience and expertise.)

In addition to competitive salaries, Vicinitas offers a comprehensive benefits package including:

  • Annual Bonuses
  • Equity Opportunities
  • Multiple Medical Plan Options
  • Dental and Vision Coverage
  • Short and Long-Term Disability Insurance
  • Group Life Insurance
  • Flexible Spending Accounts (FSA)
  • 401k Retirement Plan
  • Generous Holiday Schedule
  • Unlimited Flexible Time Off
  • Annual Year-End Shutdown

Vicinitas is committed to providing equal employment opportunities (EEO) to all employees and applicants without regard to any characteristic protected by applicable law.



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