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Research Scientist
2 months ago
Innova Solutions is seeking a highly skilled and motivated individual to join our team as a Research Associate. As a key member of our research team, you will play a critical role in conducting and analyzing hydrogen exchange experiments using mass spectrometry to analyze interactions between small molecules and target proteins.
Key Responsibilities:- Conduct and analyze various hydrogen exchange experiments on an assortment of cellular protein targets using mass spectrometry.
- Collaborate closely with computational scientists to utilize the resulting data for structural predictions.
- Support early discovery research through HDX and contribute to the development of new research projects.
- Develop and implement generic protein biochemistry workflows for specific situations, including buffer exchange, concentration measurement, serial dilutions, and buffer preparation.
- Work with a variety of chemicals, including guanidine hydrochloride, guanidine thiocyanate, hydrochloric acid, acetic acid, trifluoroacetic acid, phosphate, tris(2-carboxyethyl)phosphine, 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid, Pierce FlexMix calibration solution, pH meter calibration solution, methanol, acetonitrile, ammonium bicarbonate, carbonic acid, deuterium oxide, sodium hydroxide, sodium deuteroxide, glycine, histidine acetate, boric acid, deuterium oxide, experimental compounds synthesized on-demand at trace concentrations, peptides synthesized to order, recombinant proteins ranging in size from kilodaltons in low concentrations, and deoxyribonucleic acids.
- Detailed knowledge of mass spectrometry and standard tools utilized in protein biochemistry.
- Ability to perform buffer exchange, concentration measurement, serial dilutions, and buffer preparation.
- Previous experience with mass spectrometry and chromatographic separations.
- Experience with robotics, hydrogen exchange experiments, and/or computer programming in Python.
- Competitive pay range of $48-$58 per hour.
- Medical and pharmacy coverage.
- Dental and vision insurance.
- 401(k) plan.
- Health saving account (HSA) and flexible spending account (FSA).
- Life insurance.
- Pet insurance.
- Short-term and long-term disability.
- Accident and critical illness coverage.
- Pre-paid legal and ID theft protection.
- Sick time and paid leaves (as required by law).
- Employee Assistance Program (EAP).
