Computational Software Engineer

1 week ago


Santa Fe, New Mexico, United States Cadence Design Systems Full time

Company Overview:

Cadence Design Systems, through its division Cadence Molecular Sciences, stands at the forefront of computational molecular design. Our expertise lies in delivering rapid, robust, and scalable software solutions, alongside consulting services, highlighted by Orion – a pioneering cloud-native software-as-a-service platform for molecular modeling.

Position Overview:

In this role, you will engage with cutting-edge technologies in cloud computing, alongside Python and C++ development, to explore the intricate mechanisms of passive membrane permeability in drug-like compounds. Your contributions will significantly influence drug discovery efforts, impacting pharmaceutical and biotech sectors globally.

Key Responsibilities:

  • Develop state-of-the-art software tools aimed at enhancing drug discovery processes.
  • Conduct 3D molecular modeling, focusing on both ligand-based and structure-based design methodologies.
  • Generate bio-active conformers and model molecular properties and interactions in three dimensions.
  • Optimize molecular structures in situ and compute free energy values.
  • Assist clients in overcoming challenges related to drug discovery.

Technologies Utilized:

  • Programming Languages: Python, C++, Java, C#
  • Development Tools: CMake, SWIG, Git, Jupyter, Conda, Pip, Atlassian Suite (JIRA, Bitbucket, Fisheye)
  • Multi-platform development environments
  • Orion: A high-performance cloud platform for scientific computing

Qualifications:

  • Master's or PhD in Physics, Chemistry, Computational Biology, or a related discipline.
  • A strong desire to embrace new technologies and concepts.
  • 3-5+ years of experience in scientific development using Python and/or C++.
  • Familiarity with molecular modeling and drug discovery literature.
  • Comprehensive understanding of professional software development practices and tools.

Preferred Attributes:

  • Collaborative mindset and attention to detail.
  • Strong communication skills.
  • Innovative thinking in scientific and technical domains.
  • Curiosity and creativity in problem-solving.
  • Experience with large-scale software projects.
  • Ability to write new code when necessary and utilize existing code effectively.
  • Capability to manage development timelines while balancing features and deadlines.


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