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Computational Software Engineer
2 months ago
Company Overview:
Cadence Design Systems, through its division Cadence Molecular Sciences, stands at the forefront of computational molecular design. We specialize in delivering robust, scalable software solutions and consulting services, exemplified by our cloud-native platform, Orion. This integrated software-as-a-service platform is designed for molecular modeling, providing unparalleled capabilities for the pharmaceutical, biologics, agrochemical, and flavor industries.
Position Overview:
As a Scientific Developer, you will engage with cutting-edge technologies in cloud computing and advanced molecular dynamics simulations. Your contributions will focus on elucidating the mechanistic aspects of passive membrane permeability for drug-like compounds, potentially influencing drug discovery processes globally.
Key Responsibilities:
- Develop state-of-the-art software tools tailored for drug discovery applications.
- Conduct 3D molecular modeling, including both ligand-based and structure-based design methodologies.
- Generate bioactive conformers and model molecular properties and interactions in three dimensions.
- Optimize molecular structures in situ and compute free energy values.
- Assist clients in addressing their drug discovery challenges through innovative solutions.
Technologies Utilized:
- Programming Languages: Python, C++, Java, C#
- Development Tools: CMake, SWIG, Git, Jupyter, Conda, Atlassian tools (JIRA, Bitbucket, Fisheye)
- Environment: Multi-platform development setup
- Orion: A high-performance cloud platform for scientific computing
Qualifications:
- Master's or PhD in Physics, Chemistry, Computational Biology, or a related discipline.
- A strong desire to explore new technologies and concepts.
- 3-5+ years of experience in scientific software development using Python and/or C++.
- Familiarity with molecular modeling and drug discovery literature.
- Comprehensive understanding of professional software development practices and tools.
Preferred Attributes:
- Team-oriented mindset with attention to detail.
- Strong communication skills.
- Innovative thinking in scientific and technical domains.
- Curiosity and creativity in problem-solving.
- Experience with large-scale software projects.
- Ability to write new code and utilize existing code effectively.
- Capability to manage development timelines while balancing feature delivery.