Senior In Vivo Pharmacology Specialist

4 days ago


Cambridge, Massachusetts, United States Third Rock Ventures Full time
Senior In Vivo Pharmacology Specialist

A well-funded and highly innovative start-up from Third Rock Ventures is seeking a talented Senior In Vivo Pharmacology Specialist to join the Biology-In Vivo Pharmacology team. The ideal candidate will serve as the in vivo pharmacology representative for discovery-stage pipeline program(s) focused on antibody-driven diseases.

Key Responsibilities:

  • Design and manage in vivo biology functional experiments that support preclinical drug discovery, including PK/PD analysis, mechanism of action studies, and disease modeling.
  • Assist in managing internal in vivo pharmacology capabilities at a shared vivarium space, including some animal handling/sample collection.
  • Independently develop and execute quantitative assays for the analysis/characterization of ex vivo samples (ELISA, flow cytometry).
  • Manage out-sourced CRO-based workflows, including study design and data analysis.

Requirements:

  • Ph.D. in a relevant scientific area, such as immunology, cell/molecular biology, with 0-3 years of experience in Biotech/Pharma pharmacology groups or BA/BS in a relevant scientific area with 8+ years of experience in Biotech/Pharma industry within in vivo pharmacology.
  • Extensive experience in the design and execution of in vivo studies, particularly in assessing pharmacokinetics/pharmacodynamics (biologics experience preferred).
  • Experience in ex vivo sample analysis and data interpretation (immunophenotyping, ELISA).
  • Capacity to work within a dynamic matrix environment, with strong contribution to project strategy and execution.
  • Excellent communication, presentation, and inter-personal skills; superb organizational and problem-solving skills.


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