Research Scientist, Kidney Pharmacology Specialist

5 days ago


Cambridge, Massachusetts, United States Advanced Accelerator Applications (Italy) - S... Full time
About the Role

We are seeking a highly skilled Research Scientist to join our interdisciplinary Discovery and Translational Pharmacology group in support of our efforts to progress novel medicines toward the clinic.

Key Responsibilities
  • Design and implement in vivo and ex vivo studies to identify new therapeutic targets, with a focus on renal diseases, and to test and validate novel therapeutics for our priority diseases.
  • Conduct in vivo experiments with rodent models, primarily of kidney disease, including dosing novel therapeutics; pharmacokinetic and pharmacodynamic analyses; clinical observations including blood and urine collection; ultrasound, telemetry, and similar non-lethal readouts; and harvesting of tissues for analysis of efficacy.
  • Execute standard molecular biology techniques to evaluate therapeutic effect (such as RT-qPCR, ELISAs, and Western blots).
  • Establish collaborative working relationships with scientific partners across the Biomedical Research organization.
  • Implement established and novel technologies to ensure scientific excellence and impactful results.
  • Ability to present scientific results to project teams within DAx and in the broader Novartis community.
Requirements
  • B.A./B.S. or M.S. degree in a biological or chemical science discipline and 2+ years of relevant experience in a related field.
  • Hands-on experience with pre-clinical rodent models, including the ability to perform routine procedures including dosing (PO, IP, SC).
  • Experience with blood, urine, and tissue collection.
  • Proficiency performing biochemical assays (RT-qPCR, western blot, ELISA).
  • Ability to integrate into a highly-collaborative, multi-person team.
  • Fluency and excellent communication skills in English.
  • A desire and willingness to learn new, cutting-edge techniques.
  • Experience with rodent models of kidney disease.
  • Experience with advanced techniques related to kidney biology (eGFR, ultrasound).
Why Novartis

Our purpose is to reimagine medicine to improve and extend people's lives. Join us in this mission.

Commitment to Diversity and Inclusion /

The Novartis Group of Companies are Equal Opportunity Employers committed to maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.



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