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Senior Scientist, In Vivo Gene Editing
2 months ago
About the Role:
Editas Medicine is seeking a highly motivated and talented Associate Scientist II to join our Preclinical Discovery team. As a key member of our team, you will be responsible for developing novel gene editing strategies for in vivo gene editing programs. Your expertise in cellular and in vivo biology will be instrumental in driving the development of delivery strategies for gene editing machinery into target cells in vivo.
Key Responsibilities:
- Develop and optimize molecular assays for evaluating editing outcomes of CRISPR-based therapeutics in an in vivo context.
- Work with primary cells and cell lines to support the pharmacology of CRISPR-based therapeutics.
- Support in vivo studies for evaluation of LNP targeting and biodistribution.
- Maintain an electronic lab notebook in a timely fashion.
- Analyze and present data within the organization.
- Collaborate with internal teams to develop assays for robust detection of LNP cargo, LNP dynamics, and LNP targeting.
Requirements:
- BS/MS in Biology or related discipline and 6+/4+ years of hands-on research experience in academic and/or pharmaceutical/biotech environment.
- Skilled in molecular assays including PCR and flow cytometry. Demonstrated knowledge in assay development and optimization.
- Cell culture experience and experience with cell-based assays.
- Animal handling experience is a must.
Preferred Qualifications:
- Hematopoietic stem cell culture experience is a plus.
- Self-motivated, result-driven with excellent attention to details and ability to independently execute protocols to drive assignments to completion.
- Team oriented and excel in a fast-paced and dynamic team environment.
- Excellent oral and written communication skills.
- Well-organized and excellent at multi-tasking.
- Ability to form hypotheses, think critically, extract conclusions from datasets to inform future studies.
Benefits:
Editas Medicine provides a comprehensive array of benefits to all employees, including a Blue Cross Blue Shield PPO Medical Plan, a company-funded Health Savings Account, Dental and Vision Insurance, Life and Disability Insurance, Dependent Care Account, Tuition Reimbursement, 401(k) plan with company match, Employee Stock Purchase Plan, Employee Assistance Plan, Wellness Programs, and a flexible Paid Time Off policy.
About Editas Medicine:
Editas Medicine is a biotechnology company dedicated to bringing transformative and life-changing therapies to people living with serious diseases. Our team is driven by a collective purpose to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing to develop novel gene editing strategies for in vivo gene editing programs.
Join Our Team:
We are committed to cultivating a culture where every individual feels valued and included. If you are a results-focused and collaborative professional with a passion for advancing transformative therapies, we invite you to apply. Together, we are leading the way towards a healthier and more equitable future.
