Translational Research Scientist

2 months ago

South San Francisco, California, United States Intelliswift Software Inc Full time
About the Role

This is a molecular biology position in the Molecular Profiling group, performing gene expression profiling using targeted and NGS technologies to support basic research, preclinical and development activities, and translational biomarker work.

This high throughput lab requires an organized, highly motivated individual who is capable of multitasking projects in a collaborative environment.

Key Responsibilities
  • RNA/DNA isolation from various tissues/cells from human, non-human primate, and rodents.
  • Targeted gene expression profiling using NanoString or other RT-qPCR systems.
  • Library prep and QC of samples for use with NGS platforms.
  • NGS sequencing Illumina MiSeq and Novaseq platforms.
  • Presenting relevant data and results.
Requirements
  • B.S/B.A/M.S/PHD in biology, chemistry, biochemistry, or molecular biology.
  • Minimum 5+ years' experience in industry or academia, or equivalent combination of education and experience.
  • Knowledge in molecular biology techniques, including RNA/DNA isolation and NGS library preparation.
  • Experience with RNA/DNA QC platforms such as the Fragment analyzer, Agilent Bioanalyzer or Tapestation.
  • Experience with RT-qPCR methods and platforms.
  • Familiarity with NGS platforms, specifically Illumina MiSeq and Novaseq.
  • Ability to work up and troubleshoot new protocol methods centric to NGS platforms.
  • Good communication skills and ability to work in a team environment.
  • Ability to work independently and with minimal supervision.
  • Good organization and time management skills.
Preferred Qualifications
  • Experience with liquid automation for sample RNA/DNA isolation and NGS library prep.
  • Experience with multi-omics NGS platforms, low sorted cell populations, and/or single-cell RNAseq.
  • Experience with NGS analysis data visualization software such as Cell Ranger or BioTuring.
Familiarity with Computer Software
  • Illumina BaseSpace, Omicsoft, TIBCO Spotfire, Graphpad Prism, Ingenuity Pathway Analysis, Geneious.

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