Senior Research Scientist, Translational Medicine
3 days ago
We are seeking a highly motivated Principal Scientist to drive our biomarker discovery and drug development efforts in immunology and respiratory diseases. The successful candidate will have a strong background in translational research, with expertise in preclinical and clinical sample collection/processing and molecular/immunological techniques/methods.
Key Responsibilities
- Partner with Research Immunology to lead preclinical biomarker discovery & development efforts to support research programs using cutting-edge techniques.
- Lead efforts to support clinical trials, generate biomarker data, and lead the analysis, interpretation, and presentation of results.
- Develop biomarker strategies, integrate biomarker activities in clinical trials, and lead early and late-stage clinical development decision-enabling biomarker strategies.
- Collaborate closely with internal partners, including Research, Bioanalytical Sciences, Clinical Sciences, Preclinical and Clinical Pharmacology, Biostatistics, Regulatory, and Bioinformatics, as well as with external partners.
- Write biomarker sections of clinical and non-clinical protocols, reports, and regulatory filings, publish results in high-quality journals, and present at external conferences.
Requirements
- PhD, MD, or MD/PhD with 3+ years postdoctoral or industry experience and prior experience with translational research in Immunology, Cell Biology, Respiratory, or other related fields.
- A deep technical understanding of preclinical and clinical sample collection/processing and molecular/immunological techniques/methods, including cell culture, primary cell isolation from tissues, immunostaining, immunoassays, cytometry, molecular biology, transcriptomics, genomic sequencing, and cellular immunology.
- A record of high-quality research as demonstrated by publications in top-tier journals and external presentations.
- Strong written and verbal communication skills and demonstrated success working on cross-functional research or clinical project teams.
Preferred Qualifications
- Expertise in obstructive pulmonary diseases (e.g., COPD, bronchiectasis) or related respiratory diseases.
- Prior biostatistics or bioinformatics experience (omics, pathway, network analysis, etc.) with programming skills in Python or R.
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