Lead Scientist in CRISPR Technology

1 week ago


Village of Tarrytown, United States Regeneron Pharmaceuticals, Inc Full time

We are looking for an innovative and experienced Principal Scientist to contribute to our target discovery initiatives utilizing CRISPR methodologies. The primary duties of this role encompass the creation of cell-based screening assays, execution and evaluation of CRISPR screens utilizing mammalian cell culture systems, and the validation of prospective hits.

A typical day may involve:

  1. Developing novel CRISPR-based tools and refining CRISPR screens through genome-wide and/or targeted gRNA libraries.
  2. Engaging with cultured mammalian cell lines and primary cells.
  3. Conducting flow cytometry, including FACS, and performing immunofluorescence assays.
  4. Validating CRISPR-mediated gene editing at RNA, protein expression, and functional levels.
  5. Executing experiments with cutting-edge molecular and cellular biology techniques.
  6. Designing experiments, analyzing and visualizing data, and presenting findings in laboratory meetings and within the organization.
  7. Maintaining precise and current electronic laboratory records.

This position may be suitable for you if:

  1. You excel in a creative environment and approach challenges with innovative solutions.
  2. You possess outstanding interpersonal abilities.
  3. You demonstrate strong communication and presentation skills.
  4. You can quickly adapt, adhering to laboratory protocols with meticulous attention to detail.
  5. You are capable of working autonomously as well as collaboratively.
  6. You can efficiently engage with diverse teams, whether large or small.

To qualify for this position, you should have:

A PhD in genetics, molecular biology, or cell biology, accompanied by 5-7 years of experience post-PhD. A comprehensive understanding of CRISPR technologies and forward genetics is essential.

The candidate must exhibit expertise in tissue culture and cell engineering techniques in vitro and/or ex-vivo; familiarity with CRISPR screens is advantageous, as well as experience in data analysis and bioinformatics.

Does this resonate with you? We encourage you to consider this opportunity.

Salary Range (annually)

$124,000 - $202,800.00



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