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Principal Scientist, Immuno-Oncology
2 months ago
The Immunology & Inflammation department is seeking a skilled and ambitious Ph.D. scientist with a solid background in tumor immunology and/or autoimmunity to contribute to the discovery and development of novel therapeutics in the Cancer Immunology group at Regeneron. You will be responsible for designing and executing a variety of cell–based immunological assays and in vivo experiments using tumor and autoimmune mouse models. The successful candidate will be a member of a dynamic and creative team utilizing cutting–edge technologies to address outstanding questions in the field of cancer immunology and autoimmunity.
As a scientist in the Cancer Immunology team, activities include the following:
- Develop, optimize, and perform a variety of immunoassays to evaluate the impact of therapeutic candidates on immune cell function and phenotype, including advanced techniques such as multicolor flow cytometry and fluorescence microscopy.
- Independently plan and execute in vivo studies using tumor and autoimmune mouse models. These will include therapeutic treatment with injections through various routes (IP, IV, SC), blood and tissue collection for downstream analysis of immune responses.
- Analyze data using biological and statistical software such as OMIQ, Prism, Excel, etc.
- Work collaboratively with cross–functional scientists to drive target validation and therapeutic antibody development.
- Deliver impactful presentations to colleagues, including senior leadership.
- Write protocols and study reports, and maintain accurate electronic records.
- Routinely review relevant literature, attend scientific meetings, and maintain expertise in the field of Immunology and Immuno–Oncology.
- Train and manage research associates as needed.
This role requires a Ph.D. in immunology, immuno–oncology, or a related field with a strong record of innovation and publication and 5+ years of experience. Proven expertise in T cell biology with experience using mouse tumor and autoimmune models, including high–dimensional immunophenotyping, is required. Proficiency with fluorescence microscopy and advanced imaging techniques is a plus.
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations.
