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Senior Scientist/Principal Scientist, Biomarker Discovery and Data Science
1 month ago
Company Overview:
Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. With a strong focus on innovation and entrepreneurship, Flagship has originated and fostered over 100 scientific ventures, resulting in over $90 billion in aggregate value.
Job Summary:
We are seeking a highly skilled and motivated Senior Scientist/Principal Scientist to join our team in Biomarker Discovery and Data Science. The successful candidate will design and implement novel approaches to handling biological data, focusing on biomarkers and expanding to multiple types of molecular and clinical data. The role will involve applying machine learning to develop generalizable models for discovery of biological markers of disease progression and deploying those models in select therapeutic areas.
Key Responsibilities:
- Develop and apply bioinformatics, computational biology, and machine learning tools to generate insights and hypotheses from high-dimensional molecular datasets.
- Improve model robustness to complex comorbidities, sources of variance, technical artifacts, and noise.
- Align time-series biological data with clinically relevant inflection points identified in electronic health records, clinical trials, or other sources.
- Identify and leverage internal and external datasets to address questions critical to FL84's core objectives and generate testable hypotheses.
- Develop clear, intuitive visualizations and communicate analysis results via presentations to a multi-disciplinary audience.
- Cultivate a data-centric company philosophy by helping to maintain best practices for code development, data management, and infrastructure.
- Monitor and evaluate new and emerging technologies and models and identify opportunities for collaboration within Flagship Pioneering companies, academia, and third parties.
Requirements:
- PhD or equivalent level of experience in Computational Biology, Bioinformatics, Systems Biology, Computer Science, or related field.
- At least 5 years post-doctoral experience in academia or industry for the rank of Principal Scientist.
- Practical programming and scripting skills, preferably in Python and R.
- Demonstrable knowledge of high-dimensional -omics data and tools for their analysis.
- Self-motivated, highly collaborative, and team-oriented with an ability to thrive in an entrepreneurial and multidisciplinary environment.
- Ability to independently lead and run research projects, while maintaining close communication with team members.
- Excellent communication and presentation skills.
About Flagship:
Flagship Pioneering is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status.
We recognize that there is no perfect candidate, and we encourage applications from individuals with diverse backgrounds and experiences. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way.
