Senior Bioinformatics Scientist

4 weeks ago

Cambridge, Massachusetts, United States Flagship Ventures Full time
Unlock the Power of Computational Biology

We are seeking a highly skilled Senior Bioinformatics Scientist to join our Pioneering Medicines Translational Sciences Team. As a key member of our team, you will lead the computational efforts on drug discovery programs, integrating, analyzing, and interpreting omics data to drive target discovery, translational, and patient stratification efforts across disease areas.

Key Responsibilities:
  • Lead Translational Bioinformatics projects in various areas, including oncology, cardiovascular, renal, metabolic, and pulmonary diseases.
  • Coach other team members on strategic thinking and next-level synthesis and communication skills.
  • Propose, evaluate, and champion state-of-the-art computational omics approaches to answer key biological questions.
  • Mine genomics datasets to identify novel targets for small molecule and biological therapies.
  • Drive analyses or internalize expertise for a rich suite of data modalities: bulk and single-cell RNAseq/genomics, spatial genomics, proteomics, and state-of-the-art modeling techniques.
  • Work closely with in-vivo, in-vitro, and translational research teams to translate biological questions into analytical solutions.
  • Deliver impact to projects by identifying technical trends, both internal and external to your subject area.

Minimum Requirements:

  • Ph.D. in Bioinformatics, Computational Biology, Biological Sciences, or related discipline.
  • 4+ years of industry experience as a bioinformatics representative on drug discovery programs.
  • Understanding of biology and/or translational research and ability to address biological questions using computational approaches.
  • Succesful track record collaborating with cross-functional scientific teams.
  • Experience with state-of-the-art methods for next-generation sequencing data (NGS).
  • Experience integrating genetic, genomic, and pathway/network datasets with novel experimental data to derive biological understanding.
  • Fluency in R, Python, or any other broadly used programming languages and environments like Code Ocean, AWS, git.
  • Excellent problem-solving, teamwork, and communication skills, with an ability to effectively interact with people in a dynamic matrix environment.
  • Strong scientific curiosity and initiative.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status.

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