Cell Culture Scientist II

2 weeks ago

Seattle, Washington, United States A-Alpha Bio Full time
Position Overview

A-Alpha Bio is a pioneering drug discovery firm based in Seattle, WA, focused on revolutionizing the development of impactful therapeutics. Our approach integrates high-throughput synthetic biology to assess protein-protein interactions at scale with advanced machine learning techniques to forecast protein binding behaviors. We collaborate with top pharmaceutical and biotechnology firms to facilitate the discovery of antibodies, molecular glues, and other drugs related to protein interactions. Additionally, we leverage our laboratory and computational resources to create and advance an internal pipeline of biologics and molecular glues aimed at enhancing human health.

Note: This position requires relocation to Seattle, WA.

Compensation: $73,000 - $87,000 annually

Employment Status: Exempt

Work Environment: Onsite

Supervisor: Senior Scientist, Protein Science

Role Responsibilities

We are on a mission to enhance human health by exploring the potential of protein-protein interactions. We are currently looking for a Research Associate II to join our Protein Science team, focusing on expanding our mammalian protein production capabilities.

  • Assist in the design and assembly of antibody-like molecules for therapeutic assessment.
  • Utilize strong sterile techniques to perform mammalian cell transfections for expressing designed molecules.
  • Support the purification and characterization of proteins developed through your contributions.
Key Duties
  • Execute molecular biology protocols and create protein expression constructs.
  • Manage the upkeep of cell cultures for protein production.
  • Conduct transient transfection experiments using appropriate cell lines.
  • Prepare transfectant supernatants for subsequent protein purification processes.
  • Maintain detailed records of protein expression activities in an electronic lab notebook and update the internal protein database.
  • Engage in learning opportunities related to downstream protein characterization and functional assays.
  • Present findings and experimental outcomes during interdisciplinary team meetings.
  • Perform additional responsibilities as assigned.
Qualifications & ExperienceRequired
  • Bachelor's degree in a relevant discipline with 2+ years of experience in an industrial biotechnology setting; or an equivalent combination of education and experience.
  • Proficiency in molecular biology techniques such as Gibson Assembly.
  • Experience in designing and ordering oligonucleotides and gene fragments.
  • Familiarity with construct sequence verification.
  • Understanding of protein production processes in a startup environment.
  • Strong communication and organizational abilities.
  • Capability to collaborate within dynamic startup teams.
  • Self-driven, intellectually curious, and enthusiastic about interdisciplinary research in a fast-paced setting.
Preferred
  • Experience with transient protein expression at a small to medium scale.
  • Familiarity with specific cell culture techniques.
  • Expertise in biolayer interferometry assays.
  • Knowledge of protein biophysical characterization methods.
  • Experience in antibody formatting and optimizing protein expression.

We provide competitive compensation, including benefits, flexible time off, and equity in a rapidly growing startup. Applicants must have legal authorization to work in the United States. Currently, A-Alpha Bio is unable to offer visa sponsorship.

About A-Alpha Bio

A-Alpha Bio is a biotechnology firm that utilizes synthetic biology and machine learning to analyze, predict, and engineer protein-protein interactions. Our AlphaSeq platform employs synthetic biology to experimentally measure millions of protein interaction affinities simultaneously. This binding data is integrated into our AlphaBind platform to train machine learning models that predict binding based on sequence. We utilize both platforms to discover and refine high-impact therapeutics for our pipeline and in collaboration with leading pharmaceutical and biotechnology companies.

Founded in 2018, A-Alpha Bio emerged from the University of Washington's Institute for Protein Design and Center for Synthetic Biology, which are home to exceptional and entrepreneurial scientists. Since our inception, we have concentrated on an oncology-focused internal pipeline alongside partnerships with pharma and biotech firms to collaboratively develop predictive machine learning models and discover drugs for various therapeutic areas. New team members can expect a fast-paced, dynamic, and interdisciplinary work environment. We are committed to building a diverse, meritocratic, and supportive team that embodies our values of integrity, ambition, teamwork, and making a positive impact on the world.

A-Alpha Bio is located in a custom-designed lab and office space in downtown Seattle. While the startup lifestyle can be demanding, we prioritize work-life balance. Our region is known for its exceptional outdoor activities, including hiking, biking, climbing, skiing, kayaking, and sailing. At A-Alpha, you will find a diverse group of individuals with various interests, from outdoor enthusiasts to gamers, chefs, explorers, sports fans, and artists. Whatever your passions, you will find a place at A-Alpha Bio.

  • Research Scientist in Cell Therapy

    2 weeks ago

    Seattle, Washington, United States SSi People Full time

    Key Qualifications:Extensive expertise in creating ligand binding assays (e.g., ELISA, MSD, AlphaLISA, Simple Plex, Luminex).PhD with a minimum of 1 year of relevant industry experience is preferred.Proficient in data analysis and experimental design/method development (e.g., 96-well plate map layouts).Position Overview:The Research Scientist will...

  • Scientist - Cell Therapy Research

    1 week ago

    Seattle, Washington, United States Dexian Full time

    Job Title: Scientist - Cell Therapy ResearchLocation: RemoteDuration: 12+ monthsPay Range: $60-65/hrAbout the Role:We are seeking a highly skilled Scientist to join our Cell Therapy Research team at Dexian. As a Scientist, you will play a critical role in supporting the development of our Allogeneic Cell Therapy pipeline programs.Key...

  • Cell Therapy Research Scientist

    2 weeks ago

    Seattle, Washington, United States Integrated Resources, Inc Full time

    Job OverviewPosition Title: Cell Therapy Research ScientistLocation: Seattle, WAContract Duration: 12 Months+ (Potential for Extension)Compensation: $61.08 /hr on W2Position Summary:The Research Scientist will autonomously design and implement plate-based assays to support the development and characterization of autologous and allogenic cell therapies...

  • Cell Therapy Scientist

    7 days ago

    Seattle, Washington, United States Bristol Myers Squibb Full time

    About This RoleBristol Myers Squibb is a leading biopharmaceutical company that is reimagining the future of cell therapy. We are seeking a highly skilled and motivated Senior Associate Scientist to join our Cell Therapy team.Key ResponsibilitiesPerform analytics testing, including qPCR, ddPCR, ELISA, molecular biology, and cell-based assays to support...

  • Lead Associate Scientist in Cell Therapy

    1 week ago

    Seattle, Washington, United States Bristol Myers Squibb Full time

    About Us At Bristol Myers Squibb, we are dedicated to making a significant impact on the lives of patients through innovative therapies. Our environment fosters creativity and collaboration, where each day presents unique challenges and opportunities for growth. Our commitment to excellence drives us to achieve breakthroughs in cell therapy, making a real...

  • Lead Associate Scientist in Cell Therapy

    2 weeks ago

    Seattle, Washington, United States Bristol Myers Squibb Full time

    Join Us at Bristol Myers Squibb At Bristol Myers Squibb, we are dedicated to transforming the lives of patients through innovative science and groundbreaking therapies. Our environment is dynamic and collaborative, where every team member plays a crucial role in advancing our mission. Here, you will find opportunities to grow your career in ways that are...

  • Lead Associate Scientist in Cell Therapy

    1 week ago

    Seattle, Washington, United States Bristol Myers Squibb Full time

    Join Us at Bristol Myers Squibb Engaging. Impactful. Transformative. These are not just words; they define the experience of working at Bristol Myers Squibb. Here, every day presents unique challenges and opportunities across various departments. From enhancing production processes to pioneering advancements in cell therapy, our work profoundly impacts...

  • Research Scientist II

    2 weeks ago

    Seattle, Washington, United States ECLARO Full time

    JOB TITLE: Associate Research ScientistLocation: Seattle, WA (100% Onsite)Duration: 12 months initial (potential extension/potential right to hire)Key Competencies:• Extensive proficiency in HPLC/UPLC methodologies.• Familiarity with nanoparticle analysis techniques such as DLS, MALS-FFF, NTA, and encapsulation efficiency.• Experience in mammalian...

  • Research Scientist II

    2 weeks ago

    Seattle, Washington, United States Integrated Resources, Inc Full time

    Position OverviewWe are seeking a dedicated Research Scientist II to contribute to our innovative projects in a dynamic research environment.Job LocationSeattle, WAContract Duration12 Months+Compensation$67.74/Hr. on W2Essential Skills Expertise in generating and analyzing qPCR and RT-PCR datasets Familiarity with capillary electrophoresis (preferably using...

  • Cell Therapy Research Associate

    2 weeks ago

    Seattle, Washington, United States Integrated Resources, Inc ( IRI ) Full time

    Position: Associate Research ScientistCompany: Integrated Resources, Inc (IRI)Location: Seattle, WAContract Duration: 12 monthsEssential Qualifications:• Bachelor’s degree in biological sciences, immunology, or a related field with a minimum of 2 years of pertinent experience, preferably in an industrial setting.• Alternatively, a Master’s degree...

  • Cell Therapy Research Associate

    2 weeks ago

    Seattle, Washington, United States Integrated Resources, Inc ( IRI ) Full time

    Position: Associate Research ScientistCompany: Integrated Resources, Inc (IRI)Duration: 12 monthsEssential Qualifications: • A Bachelor’s degree in biological sciences, immunology, or a related field with a minimum of 2 years of pertinent experience; industrial exposure is advantageous. • Alternatively, a Master’s degree with at least 1 year of...

  • Cell Therapy Developer

    1 week ago

    Seattle, Washington, United States TSR Consulting Services, Inc. Full time

    Job SummaryTSR Consulting Services, Inc. is seeking a highly skilled Assistant / Associate Scientist to join our team in a contracting role. As a key member of our scientific team, you will be responsible for performing studies, developing, and optimizing unit operations to support process and platform development programs.Key ResponsibilitiesDesign and...

  • Lead Research Scientist in Cell Therapy

    2 weeks ago

    Seattle, Washington, United States ECLARO Full time

    JOB TITLE: Senior Research AssociateLocation: Seattle, WA (ONSITE)Duration: 12 months initial (potential extension/potential right to hire)Work Schedule: Mon – Fri, Business Hours*Flexibility is required as needed for extended hours or weekends based on business requirements*KEY QUALIFICATIONSProficiency in cell-based assays including flow cytometry,...

  • Lead Research Scientist in Cell Therapy

    2 weeks ago

    Seattle, Washington, United States ECLARO Full time

    POSITION: Senior Research AssociateLocation: Seattle, WA (ONSITE)Contract Duration: Initial 12 months (with potential for extension or conversion)Work Schedule: Monday to Friday, Standard Business Hours*Flexibility is required for extended hours or weekends based on business needs*KEY SKILLS REQUIRED:Proficiency in cell-based assays including flow cytometry,...

  • Senior Scientist – Technology Innovation

    2 weeks ago

    Seattle, Washington, United States Allen Institute for Cell Science Full time

    The Allen Institute for Cell Science is dedicated to unraveling the intricacies of cellular biology to enhance our understanding and improve human health outcomes. Through a collaborative, open-science approach, we strive to propel foundational research, establish standards and models, and foster innovative ideas that can lead to significant advancements in...

  • Data Scientist II

    3 months ago

    Seattle, Washington, United States Amazon Full time

    Data Scientist IIJob ID: | Services LLCDESCRIPTIONThe Support Product and Services (SP&S) team focuses on improving advertisers support experience driving self-service support and contact support operations. The Support Products and Services team's vision is to empower Advertisers with the right assistance at the right time to enable them to confidently and...

  • Junior Research Scientist

    2 weeks ago

    Seattle, Washington, United States Innova Solutions Full time

    Junior Research Scientist - Biotechnology/R&D/Scientific ResearchJob Overview:Innova Solutions is seeking a dedicated Junior Research Scientist to join our dynamic team. This role is pivotal in supporting our research initiatives in the biotechnology sector.Key Responsibilities:Conduct routine evaluations of vector samples to assess quality characteristics...

  • Junior Research Scientist

    2 weeks ago

    Seattle, Washington, United States Tendencys Innovatios Full time

    Position: Associate Research ScientistCompany: Tendencys InnovationsJob Type: ContractLocation: OnsiteDuration: 12 monthsCompensation: $56 - $58 per hourRole Overview:As an Associate Research Scientist, your primary responsibilities will include:Conducting routine analyses of vector samples to assess quality attributes, supporting process development studies...

  • Junior Research Scientist

    2 weeks ago

    Seattle, Washington, United States Innova Solutions Full time

    Innova Solutions is seeking a Research Scientist AssociateJob Title: Research Scientist AssociatePosition Type: Full-time ContractDuration: 12 MonthsLocation: Seattle, WA OnsitePay Range: $65.52 /Per HourAs a Research Scientist Associate, your responsibilities will include:Key Skills:Proven experience with HPLC/UPLC methodologies.Familiarity with...

  • Junior Research Scientist in Biotechnology

    2 weeks ago

    Seattle, Washington, United States Tendencys Innovatios Full time

    Position: Junior Research ScientistCompany: Tendencys InnovatiosJob Type: ContractLocation: OnsiteOverview:As a Junior Research Scientist, you will engage in the routine evaluation of vector samples to assess quality attributes, contributing to process development studies through various biophysical methodologies and cellular assays.Key...