Research Scientist, Translational Medicine
5 days ago
Bicycle Therapeutics Limited is a clinical-stage biopharmaceutical company dedicated to developing innovative medicines for underserved diseases. We are seeking a highly skilled Research Scientist to join our Translational Sciences team.
Job SummaryThe successful candidate will be responsible for overseeing data generation, analysis, and interpretation of clinical protocol-defined biomarker assays, managing clinical trial biomarker samples, and overseeing external assay development projects at Contract Research Organizations (CROs). This is a key role in our multifaceted team that works seamlessly across research and clinical functions to support clinical biomarker strategies.
Key Responsibilities- Design, conduct, and coordinate translational research activities at CROs, including assay development, execution, and analysis of clinical biomarker data.
- Identify, evaluate, and prioritize candidate predictive & pharmacodynamic biomarkers to support clinical development strategies.
- Support analysis and development of clinical biomarker datasets, including Next-Generation Sequencing (NGS), Immunohistochemistry (IHC), and In Situ Hybridization (ISH).
- Essential requirements:
- Experience with design, delivery, analysis, and interpretation of clinical biomarker assay techniques (e.g., comprehensive genomic profiling/NGS, ISH, and/or IHC).
- Clinical biomarker assay development experience in solid tumor/liquid biopsies.
- Demonstrated experience managing external projects at CROs.
- Translational science, translational medicine, or clinical research experience.
- Ability to collaborate, communicate, and present findings to scientists and non-scientists.
- Flexible, organized, and motivated scientist who enjoys working in a fast-paced, small company environment.
- Flexible working environment.
- Competitive reward, including annual company bonus.
- Medical, dental, and vision insurance for eligible employees and their families, with 100% of the premiums covered by the Company.
- Health and Dependent Care Flexible Spending Accounts.
- 401(k) plan with a 4% Company match and immediate vesting.
- Eligibility to accrue up to 23 paid time off days per full year worked, plus the option to buy up to 5 additional days.
- Employee assistance program.
- Employee recognition schemes.
- 10 Company holidays.
- Competitive Family Leave Policy.
- Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.
Bicycle Therapeutics Limited is an equal opportunities employer and welcomes applications from all qualified candidates. We are committed to building a diverse workforce that is representative of the communities we serve.
-
Research Scientist, Translational Sciences
4 weeks ago
Cambridge, Massachusetts, United States Bicycle Therapeutics Full timeJob Title: Research Scientist, Translational SciencesAt Bicycle Therapeutics, we are seeking a highly skilled Research Scientist to join our Translational Sciences team. As a key member of our team, you will be responsible for overseeing data generation, analysis, and interpretation of clinical protocol-defined biomarker assays, managing clinical trial...
-
Research Scientist, Translational Sciences
3 weeks ago
Cambridge, Massachusetts, United States Bicycle Therapeutics Full timeJob Title: Research Scientist, Translational SciencesAt Bicycle Therapeutics, we are seeking a highly skilled Research Scientist to join our Translational Sciences team. As a key member of our team, you will be responsible for overseeing data generation, analysis, and interpretation of clinical protocol-defined biomarker assays, managing clinical trial...
-
Cambridge, Massachusetts, United States Bicycle Therapeutics Limited Full timeJob DescriptionThe Research Scientist will be primarily responsible for overseeing data generation, analysis, and interpretation of clinical protocol defined biomarker assays, managing clinical trial biomarker samples, and overseeing external assay development projects at CROs.The successful candidate will be a key member of a multifaceted team that works...
-
Cambridge, Massachusetts, United States Moderna Therapeutics Full timeAbout the RoleWe are seeking a highly experienced and accomplished Director of Translational Research to join our Cancer Vaccine Research team at Moderna Therapeutics. As a key member of our research organization, you will be responsible for leading a team of scientists and researchers in the design, implementation, and execution of translational research...
-
Head of Biology and Translational Research
4 days ago
Cambridge, Massachusetts, United States Flagship Ventures Full timeJob SummaryFlagship Pioneering is seeking a visionary leader to spearhead our bioplatform innovation efforts. As the Head of Biology, you will be responsible for driving platform development, therapeutic target discovery, and validation. Your expertise in molecular and cellular biology, combined with your ability to lead and manage a team of scientists, will...
-
Cambridge, Massachusetts, United States Bristol Myers Squibb Full timeTransforming Patients' Lives through ScienceBristol Myers Squibb is a leading pharmaceutical company dedicated to transforming patients' lives through science. We are seeking a highly skilled and experienced Associate Director/Sr. Principal Scientist of Translational Medicine to join our team.The successful candidate will be responsible for leading...
-
Senior Translational Medicine Leader
4 weeks ago
Cambridge, Massachusetts, United States Astellas Pharma Full timeAbout the RoleWe are seeking a highly skilled and experienced Group Leader, Translational Medicine to join our team at Astellas Pharma. As a key member of our Translational Medicine team, you will be responsible for leading the development and implementation of our Translational Medicine strategy within a defined disease or primary focus area.Key...
-
Senior Translational Medicine Leader
3 days ago
Cambridge, Massachusetts, United States Astellas Pharma Full timeAbout the RoleWe are seeking a highly experienced and skilled Group Leader, Translational Medicine to join our team at Astellas Pharma. In this role, you will be responsible for leading the development and implementation of the Translational Medicine strategy within a defined disease or primary focus area.Key ResponsibilitiesLead a team of Translational...
-
Translational Medicine Group Leader
2 weeks ago
Cambridge, Massachusetts, United States Astellas Pharma, Inc. Full timeJob Title: Translational Medicine Group LeaderAstellas Pharma, Inc. is seeking a highly skilled and experienced Translational Medicine Group Leader to join our team. As a key member of our organization, you will be responsible for leading the development and implementation of the Translational Medicine strategy within a defined disease or primary focus...
-
Cambridge, Massachusetts, United States Bristol-Myers Squibb Full timeJob SummaryWe are seeking a highly skilled and experienced Associate Director/Senior Principal Scientist of Translational Medicine to join our team at Bristol-Myers Squibb. As a key member of our late-stage Translational Medicine group, you will be responsible for leading biomarker and clinical activities to support drug development programs in...
-
Research Scientist
4 weeks ago
Cambridge, Massachusetts, United States Mitsubishi Electric Research Labs Full timeJob Title: Research ScientistMitsubishi Electric Research Labs, Inc. is seeking a highly skilled Research Scientist to join our Electric Systems Automation team. As a key member of our team, you will conduct original research to advance the state-of-the-art in control and learning theory for industrial process planning, process optimization, and factory...
-
Research Scientist
4 weeks ago
Cambridge, Massachusetts, United States Mitsubishi Electric Research Labs Full timeJob Title: Research ScientistMitsubishi Electric Research Labs, Inc. is seeking a highly skilled Research Scientist to join our Optimization and Intelligent Robotics team.The successful candidate will be responsible for conducting innovative research in optimization algorithms, developing a research agenda impacting both the scientific community and the...
-
Translational Medicine Group Leader
4 days ago
Cambridge, Massachusetts, United States Astellas Pharma Full timeJob SummaryThe Translational Medicine Group Leader will lead the development and implementation of the Translational Medicine strategy within a defined disease or primary focus area. This position is responsible for developing the translational strategies for Astellas assets, taking accountability for day-to-day delivery aligned with approved...
-
Clinical Research Assistant
13 hours ago
Cambridge, Massachusetts, United States Prime Medicine Full timeJob Summary:Prime Medicine is seeking a highly motivated and detail-oriented Clinical Research Assistant to join our team. As a Clinical Research Assistant, you will play a key role in advancing biomarker strategies for early development and clinical stage programs at Prime Medicine. You will gain hands-on experience in various aspects of biomarker research,...
-
CNS Biomarker Research Scientist
2 months ago
Cambridge, Massachusetts, United States QurAlis Full timeABOUT QURALISQurAlis is at the forefront of neurobiology, striving to revolutionize the treatment landscape for neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our foundation is built on a team of esteemed neurobiologists from Harvard Medical School and Harvard University, dedicated to the discovery...
-
Research Scientist, Kidney Pharmacology
4 days ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Title: Research Scientist, Kidney PharmacologyJob Summary:We are seeking a highly motivated Research Scientist to join our interdisciplinary Discovery and Translational Pharmacology group in support of our efforts to progress novel medicines toward the clinic. This role will involve designing and implementing in vivo and ex vivo studies to identify new...
-
Research Scientist Cell Pharmacology
4 days ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Title: Research Scientist, Cell PharmacologyWe are seeking a highly motivated Research Scientist to join our Cell Pharmacology team at Novartis. As a key member of our team, you will contribute to advancing our understanding of disease biology, support target identification efforts, and work towards the discovery and optimization of new drugs for CVM.Key...
-
Senior Translational Data Scientist
4 weeks ago
Cambridge, Massachusetts, United States Bicycle Therapeutics Full timeJob Title: Senior Translational Data ScientistJob SummaryBicycle Therapeutics is seeking a highly skilled Senior Translational Data Scientist to join our Translational Sciences team. As a key member of our team, you will be responsible for leading the development, customization, and maintenance of a biomarker software solution to support our clinical-stage...
-
Research Scientist
4 days ago
Cambridge, Massachusetts, United States Novartis Group Companies Full timeJob Description SummaryWe are seeking a highly motivated Research Scientist to join our Cell Pharmacology team. The successful candidate will contribute to advancing our understanding of disease biology, target identification efforts, and the discovery and optimization of new drugs for CVM.Key Responsibilities:Support target identification, validation, and...
-
Research Scientist
3 weeks ago
Cambridge, Massachusetts, United States Mitsubishi Electric Research Labs Full timeJob OpportunityMitsubishi Electric Research Labs, Inc. is seeking a highly skilled Research Scientist to join our Electric Systems Automation team. As a premier research laboratory, we conduct application-motivated research and development that advances the frontiers of technology and makes lasting impacts on the world.Our team conducts fundamental research...