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Senior Translational Data Scientist

2 months ago

Cambridge, Massachusetts, United States Bicycle Therapeutics Full time
Job Title: Senior Translational Data ScientistJob Summary

Bicycle Therapeutics is seeking a highly skilled Senior Translational Data Scientist to join our Translational Sciences team. As a key member of our team, you will be responsible for leading the development, customization, and maintenance of a biomarker software solution to support our clinical-stage oncology portfolio assets.

Key Responsibilities
  • Lead the development, customization, and maintenance of a biomarker software solution to support clinical-stage oncology assets
    • Technically contribute to and strategically manage external programmers to develop data ingestion, processing, and wrangling pipelines
    • Lead the migration of internal R-scripts and Shiny apps onto the software solution
    • Support the integration, analysis, and visualization of biomarker and clinical data within and across targeted toxins and immune-oncology clinical trial programs
    • Provide platform training and support to Bicycle scientists
  • Support data management and integration of translationally focused preclinical and clinical datasets (e.g. Nanostring, NGS)
  • Support reverse translation analytics activities by integrating relevant internal and external datasets as well as developing clear analyses and visualizations
  • Work in a cross-functional environment and communicate effectively across project teams that consist of data scientists, translational scientists, IT managers/analysts, pharmacologists, clinical
  • Effectively document data transfer specs, R scripts, and data analysis processes
Requirements
  • Experience building, customizing, and/or using clinical biomarker software solutions
  • Strong computational skillset, including proficiency in at least one coding language (ideally R), and ability to perform the following tasks:
    • data ingestion, wrangling, integration, and analysis
    • design (both strategically and technically) bioinformatics pipelines
    • development of clear and effective data visualizations
    • understanding of Shiny apps (or other UI strategies)
  • Strong software engineering skills including familiarity with AWS, Posit, and Gitlab
  • Strong bioinformatics skills including experience analyzing sequencing data
  • Familiarity with the oncology field and oncology-focused biomarker datasets
  • Takes initiative, ask questions, and independently moves projects along in a fast-paced environment
  • Team player, conscientious, organized, and creative
What We Offer
  • Flexible working environment
  • Competitive reward including annual company bonus
  • Medical, dental, and vision insurance for eligible employees and their families with 100% of the premiums covered by the Company
  • Health and Dependent Care Flexible Spending Accounts
  • 401(k) plan with a 4% Company match and immediate vesting
  • Eligibility to accrue up to 23 paid time off days per full year worked, plus the option to buy up to 5 additional days
  • Employee assistance program
  • Employee recognition schemes
  • 10 Company holidays
  • Competitive Family Leave Policy
  • Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.

Bicycle Therapeutics is an equal opportunities employer and welcomes applications from all qualified candidates.