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Translational Medicine Group Leader
1 month ago
The Translational Medicine Group Leader will lead the development and implementation of the Translational Medicine strategy within a defined disease or primary focus area. This position is responsible for developing the translational strategies for Astellas assets, taking accountability for day-to-day delivery aligned with approved plans/budgets.
Key Responsibilities- Leads a team of Translational Medicine scientists, within a defined disease or primary focus area, to advance Astellas therapeutic area pipeline from Candidate Nomination (CN) to Proof-of-Concept (POC) to commercial launch.
- Develops a portfolio level Translational Medicine strategy informed by disease insights and benchmarked against key competitors.
- Partners with Primary Focus (PF) Development to contribute to design of overall development strategy and trial design, incorporating biomarker endpoints.
- Represents Translational Medicine on PF-LT and provides scientific and strategic guidance to portfolio and asset teams, including business development strategic partnerships.
- Builds and maintains strong internal and external collaborations including partnership with Research to drive increased quality of CN candidates.
- Drives innovation and incorporates new approaches and cutting-edge technologies to increase PTRS and efficiency.
- Provides optimal project resourcing and supports delivery of portfolio by targeting key project issues aligned with overall portfolio prioritization.
- Mentors and supports team members to develop high levels of productivity and engagement whilst also responsible for performance management of the group.
- Advanced science degree (PhD, PharmD, or MD).
- Typically 12+ years of relevant experience in drug discovery and development in biotech/pharmaceutical company or equivalent translational research experience at an academic institution.
- First-hand experience in the identification and validation of pharmacodynamic and patient selection biomarkers, biomarker assay qualification and clinical implementation.
- Extensive early development experience and demonstrated success in generating Translational Science/Translational Medicine deliverables that contributed to POC.
- A strong track record in delivering high quality translational science and clinical biomarker data to inform decisions and development strategy.
- Broad technical experience in commonly used biomarker assay technologies and fit-for-purpose assay qualification/validation.
- An innovation mindset with track record of incorporating new technologies in translational and biomarker research.
- Proven record of leading teams, developing people and obtaining high quality and timely results through influencing in a matrix environment.
This position is a hybrid role and can be based in US, Japan, UK or EU. Co-location within a globally recognized scientific center of excellence would be considered advantageous.
Astellas Pharma is committed to equality of opportunity in all aspects of employment.
