Senior Translational Medicine Leader
2 days ago
We are seeking a highly skilled and experienced Group Leader, Translational Medicine to join our team at Astellas Pharma. As a key member of our Translational Medicine team, you will be responsible for leading the development and implementation of our Translational Medicine strategy within a defined disease or primary focus area.
Key Responsibilities- Lead a team of Translational Medicine scientists to advance our therapeutic area pipeline from Candidate Nomination to Proof-of-Concept to commercial launch.
- Develop a portfolio-level Translational Medicine strategy informed by disease insights and benchmarked against key competitors.
- Partner with Primary Focus Development to contribute to the design of overall development strategy and trial design, incorporating biomarker endpoints.
- Represent Translational Medicine on PF-LT and provide scientific and strategic guidance to portfolio and asset teams, including business development strategic partnerships.
- Build and maintain strong internal and external collaborations, including partnerships with Research to drive increased quality of CN candidates.
- Drive innovation and incorporate new approaches and cutting-edge technologies to increase PTRS and efficiency.
- Provide optimal project resourcing and support delivery of portfolio by targeting key project issues aligned with overall portfolio prioritization.
- Mentor and support team members to develop high levels of productivity and engagement, while also responsible for performance management of the group.
- Advanced science degree (PhD, PharmD, or MD).
- Typically 12+ years of relevant experience in drug discovery and development in biotech/pharmaceutical company or equivalent translational research experience at an academic institution.
- First-hand experience in the identification and validation of pharmacodynamic and patient selection biomarkers, biomarker assay qualification and clinical implementation.
- Extensive early development experience and demonstrated success in generating Translational Science/Translational Medicine deliverables that contributed to POC.
- A strong track record in delivering high-quality translational science and clinical biomarker data to inform decisions and development strategy.
- Broad technical experience in commonly used biomarker assay technologies and fit-for-purpose assay qualification/validation.
- An innovation mindset with a track record of incorporating new technologies in translational and biomarker research.
- Proven record of leading teams, developing people, and obtaining high-quality and timely results through influencing in a matrix environment.
This position is a hybrid role and can be based in the US, Japan, UK, or EU. Co-location within a globally recognized scientific center of excellence would be considered advantageous. At Astellas, we recognize the importance of work-life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home.
Benefits- Medical, Dental, and Vision Insurance
- Generous Paid Time Off options, including Vacation, Sick time, plus national holidays
- 401(k) match and annual company contribution
- Company-paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long-Term Incentive Plan for eligible positions
- Referral bonus program
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