Senior Manager, Clinical Pharmacology South San Francisco

2 days ago


San Francisco, California, United States Pliantrx Full time
Job Title: Senior Manager, Clinical Pharmacology

Pliant Therapeutics is a leading biopharmaceutical company focused on the discovery and development of novel therapies for fibrotic diseases. As a Senior Manager, Clinical Pharmacology, you will play a critical role in shaping the company's clinical pharmacology strategy and ensuring the successful development of our pipeline.

Key Responsibilities:
  • Develop and execute clinical pharmacology plans for multiple indications, including fibrotic diseases.
  • Provide scientific input into study design, protocol development, and data analysis.
  • Collaborate with cross-functional teams to ensure seamless execution of clinical studies.
  • Develop and maintain relationships with contract research organizations and bioanalytic vendors.
  • Stay up-to-date with regulatory requirements and ensure compliance with GCP, company SOPs, and governing laws.
Requirements:
  • PhD degree in pharmaceutics, pharmacokinetics, pharmacology, or related discipline.
  • 4+ years of biotech/pharma drug development experience with deep expertise in clinical pharmacology.
  • Excellent working knowledge of clinical pharmacology, pharmacokinetics, pharmacodynamics, and translational medicine.
  • Strong understanding of modeling and simulation, population PK, PK/PD, and PBPK modeling concepts.
  • Experience with pharmacokinetics for small molecules and direct experience leveraging modeling and simulation to facilitate compound development and registration.
What We Offer:
  • Competitive annual base salary: $180K - $190K.
  • Benefits, equity, and annual target bonus for full-time positions.
  • Opportunity to work with a leading biopharmaceutical company in the fibrotic diseases space.
  • Collaborative and dynamic work environment.


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