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Translational Research Specialist II
2 months ago
Position: Translational Research Scientist II Associate
Location: South San Francisco, CA
Qualifications:
Educational Background:
B.S/B.A/M.S/Ph.D. in biology, chemistry, biochemistry, or molecular biology.
Experience Requirements:
- B.S/B.A with a minimum of 7+ years; Masters with 5+ years; Ph.D. with 3-4 years of relevant experience in industry or academia.
Essential Laboratory Skills:
- Proficiency in molecular biology techniques, including RNA/DNA isolation and NGS library preparation.
- Familiarity with RNA/DNA quality control platforms such as the Fragment Analyzer, Agilent Bioanalyzer, or Tapestation.
- Competence in RT-qPCR methods and platforms.
- Understanding of NGS platforms, particularly Illumina MiSeq and Novaseq.
- Knowledge of NGS data quality control and analysis workflows.
- Ability to develop and troubleshoot new protocols related to NGS platforms.
- Strong communication skills and comfort in a collaborative team setting.
- Capacity to work independently with minimal supervision.
- Excellent organizational and time management abilities.
Preferred Skills and Experience:
- Experience with liquid handling automation for RNA/DNA isolation and NGS library preparation.
- Familiarity with multi-omics NGS platforms, low sorted cell populations, and/or single-cell RNA sequencing.
Software Proficiency:
- Experience with NGS analysis data visualization tools such as Cell Ranger or BioTuring.
- Knowledge of software applications: Illumina BaseSpace, Omicsoft, TIBCO Spotfire, GraphPad Prism, Ingenuity Pathway Analysis, Geneious.
Personal Attributes:
- Collaborative mindset
- Team-oriented
- Highly organized
- Capable of multitasking
- Comfortable in cross-functional team environments
- Positive attitude
- Excellent communication skills
Key Responsibilities:
This role involves working within the Molecular Profiling group, focusing on gene expression profiling utilizing targeted and NGS technologies to support fundamental research, preclinical, and development activities, as well as translational biomarker initiatives.
The position demands a highly organized and motivated individual capable of managing multiple projects in a collaborative laboratory environment.
Core Duties Include:
- RNA/DNA extraction from various biological samples.
- Targeted gene expression profiling using NanoString or other RT-qPCR systems.
- Library preparation and quality control of samples for NGS applications.
- NGS sequencing on Illumina MiSeq and Novaseq platforms.
- Presentation of relevant data and findings.
