Advisor - Peptide Discovery (San Diego, CA)
3 weeks ago
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
The Biotechnology Discovery Research group at Lilly's Biotechnology Center in San Diego discovers medicines that address significant unmet needs by integrating biology with innovative scientific capabilities in peptide, protein engineering and computational sciences. We collaborate with colleagues in both the discovery and development organizations, including scientists in therapeutic area biology, biomolecule formulation and developability, ADME, Toxicology, PK/PD, Statistics, Computational Sciences, clinical development, and more.
This is a technical position in the Peptide Discovery Team within Lilly Biotechnology Center in San Diego. The individual should demonstrate expertise in Display technology platforms to lead/support peptide discovery. The candidate will be an integral part of an innovative and interdisciplinary team that utilizes phage and mRNA display platforms to enable de novo peptide discovery and support peptide optimization at Lilly. The successful candidate must show a track record of innovation behavior, scientific curiosity, and desire to learn and implement new technologies and platforms. Excellent interpersonal, communication, and organizational skills are required for this position.
Key objectives and deliverables
Design and perform phage and mRNA display selections to identify target specific peptide therapeutics.
Design new libraries and codon boxes for Phage and mRNA display selections.
Hit characterization and optimization using different display technologies. The responsibility expands to improving affinity, potency, solubility, and introducing drug-like attributes of therapeutic peptides.
Integrate computational and structure-based information with display technologies for hit-to-lead optimization.
Collaborate and effectively communicate with project teams, cross-functional teams, and the Peptide Discovery team members.
Present data on regular basis in various internal meetings
Diligently maintain detailed, and well-organized records of experiments using Electronic Notebooks.
Requirements
Ph.D and/or postdoc in Chemistry, Biomedical Science, Biochemistry, Biotechnology, or a related subject with 0 to 4 years of industry experience and a strong focus on affinity driven selections to identify peptide hits and/or peptide synthesis.Master's degree with a minimum of 5 years of relevant experience in industry or Bachelor's degree with 10+ years of experience.
Additional Preferences Deep expertise in the incorporation of non-canonical amino acids into peptides or proteins using in vitro translation systems.
Deep understanding of molecular biology techniques to construct small- and large-scale peptide display libraries.
Knowledge and experience in peptide chemistry and synthesis.
Knowledge and experience in the use of computational methods during peptide hit-to-lead optimization. Knowledge with FACS and flow cytometry.
Self-motivated, strong work ethic, independent and results-oriented.
Ability to work independently as well as in cross-functional team settings.
Self-driven, imaginative, organized, focused, and able to work as part of a high-performing, high-paced team.
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women's Network, Working and Living with Disabilities. Learn more about all of our groups.
#WeAreLilly
-
Beach Lifeguard
3 days ago
San Diego, California, United States City of San Diego, CA Full timeJob SummaryWe are seeking highly skilled and dedicated individuals to join our team as Lifeguards in the City of San Diego, CA. As a Lifeguard, you will be responsible for ensuring the safety of beachgoers and swimmers, performing rescues, administering first aid, and enforcing aquatic beach regulations.Key ResponsibilitiesGuard swimmers at public beaches...
-
Audiologist - San Diego, CA
2 months ago
San Diego, California, United States San Diego Ear, Nose, & Throat Specialists Full timeAudiologists: Bring your excellent clinical skills and passion for patient care to Carlsbad, CaliforniaAt San Diego Ear, Nose & Throat, we are hiring a full-time or part-time Audio
-
Law Enforcement Professional
3 days ago
San Diego, California, United States Port of San Diego, CA Full timeJob SummaryWe are seeking a highly skilled and dedicated Law Enforcement Professional to join our team at the Port of San Diego. As a Harbor Police Officer, you will be responsible for maintaining law and order within the Port's jurisdiction, ensuring the safety and security of our employees, visitors, and assets.Key ResponsibilitiesPerform armed patrol of...
-
Home Care Aide
3 days ago
San Diego, California, United States A Caring Touch Home Care - San Diego, CA Full timeJob Summary: A Caring Touch Home Care - San Diego, CA is seeking a compassionate and experienced caregiver to provide companionship care to our clients in San Diego County.About the Role: As a caregiver, you will be responsible for engaging in activities with our clients, assisting with light housekeeping, dressing, bathing, and medication reminders. You...
-
San Diego, CA
1 month ago
San Diego, California, United States ProCare Therapy Full timeMinimum 1+ years speech therapy experience required.Speech Language Pathologist Needed In California | 24-25SYActively InterviewingWe are currently seeking an enthusiastic School Speech Pathologist to join our team in San Diego, CA. This role involves working alongside school administrators, teachers, and parents to deliver vital speech and language services...
-
Chief Executive Officer
21 hours ago
San Diego, California, United States Port of San Diego, CA Full timeAbout the Port of San DiegoThe Port of San Diego is a leading maritime and economic hub, managing San Diego Bay and its surrounding waterfront land. With a rich history dating back to 1962, the Port oversees two maritime cargo terminals, two cruise ship terminals, 22 public parks, and leases nearly 800 businesses around the bay.Our MissionThe Port of San...
-
In-Home Caregiver
14 hours ago
San Diego, California, United States Senior Helpers - San Diego Full timeJob OverviewWe are seeking a compassionate and dedicated In-Home Caregiver to join our team at Senior Helpers - San Diego. As a caregiver, you will play a vital role in providing high-quality care and support to seniors in their own homes.Key ResponsibilitiesAssist with personal care activities, such as bathing, dressing, and groomingPrepare meals and snacks...
-
San Diego, California, United States Cardiovascular Institute of San Diego Full timePosition: RadiologistLocation: San Diego, CAAbout Our Clinic: We are a state-of-the-art imaging clinic located in the heart of San Diego, committed to providing exceptional diagnostic services in a patient-focused environment. Our facility is equipped with the latest in imaging technology, and we take pride in maintaining a supportive and collaborative...
-
Marketing Lecturer Pool
3 days ago
San Diego, California, United States San Diego State University Full timeJob SummaryThe Department of Marketing at San Diego State University is seeking qualified candidates for part-time lecturer positions in marketing. As a lecturer, you will be responsible for teaching undergraduate and graduate courses in marketing, as well as advising students and participating in departmental service activities.ResponsibilitiesTeach...
-
San Diego Market Leader
3 days ago
San Diego, California, United States Dave's Hot Chicken San Diego Full timeJob DescriptionThe Director of Operations is a key role at Dave's Hot Chicken San Diego, responsible for overseeing the day-to-day operations and long-term success of our San Diego locations. This position leads and manages the Restaurant General Managers to help achieve the goals and objectives of our San Diego market.Key Responsibilities:Support strategic...
-
Legal Aid Professional
4 days ago
San Diego, California, United States Legal Aid Society Of San Diego Full timeJob SummaryWe are seeking a highly skilled and dedicated Staff Attorney to join our team at the Legal Aid Society of San Diego. As a Staff Attorney, you will play a critical role in providing legal services to low-income individuals and families in San Diego County.Key ResponsibilitiesSupervise and review cases generated through a legal advice hotline...
-
Caregiver for Seniors in North County San Diego
12 hours ago
San Diego, California, United States Qualicare North County San Diego Full timeJob DescriptionWork Near Your Home as a Caregiver for Seniors in North County San DiegoCompetitive Pay: $19-$22/hourPPE ProvidedMultiple Cities Served:North County San Diego: Oceanside, Vista, San Marcos, Escondido, Fallbrook, Poway, Carlsbad, Encinitas, Solana Beach, and Del Mar.Rest of San Diego County: City of San Diego, Chula Vista, Coronado, El Cajon,...
-
Caregiver - Senior Helpers San Diego
19 hours ago
San Diego, California, United States Senior Helpers - San Diego Full timeJob DescriptionJob Summary:We are seeking a compassionate and dedicated Caregiver to join our team at Senior Helpers - San Diego. As a Caregiver, you will provide high-quality, personalized care to our clients in the comfort of their own homes. If you are passionate about helping others and making a difference in someone's life, we encourage you to...
-
Wastewater Management Specialist
3 days ago
San Diego, California, United States County of San Diego Full timeJob SummaryCounty of San Diego is seeking a highly skilled Wastewater Treatment Plant Operator III to join our Operations & Maintenance team. As a key member of our team, you will be responsible for operating, maintaining, and repairing our wastewater treatment plants and sewer pump stations.Key Responsibilities:Operate and maintain complex wastewater...
-
Server - Water Grill San Diego
16 hours ago
San Diego, California, United States Water Grill San Diego Full timeJob DescriptionOverviewWater Grill San Diego is seeking a skilled and enthusiastic Server to join our team. As a Server, you will be responsible for providing exceptional customer service, ensuring a memorable dining experience for our guests, and contributing to the success of our restaurant.Key ResponsibilitiesTake food and beverage orders from guests,...
-
Host/Hostess - Water Grill San Diego
1 day ago
San Diego, California, United States Water Grill San Diego Full timeJob SummaryWe are seeking a highly skilled and customer-focused Host/Hostess to join our team at Water Grill San Diego. As a Front Desk Crewmember, you will be the first point of contact for our guests and will play a critical role in setting the tone for their dining experience.Key ResponsibilitiesGuest Service: Provide exceptional customer service to all...
-
Caregiver for Seniors in North County San Diego
17 hours ago
San Diego, California, United States Qualicare North County San Diego Full timeJob DescriptionWork Near Your Home as a Caregiver for Seniors in North County San DiegoCompetitive Pay and BenefitsQualicare North County San Diego is seeking several Caregivers to join our team. As a Caregiver, you will provide high-quality care and support to seniors in their homes.Responsibilities:Provide personal care and assistance to seniors with daily...
-
Lead Legal Advisor or Senior Legal Counsel
6 days ago
San Diego, California, United States San Diego Community Power Full timeJob OverviewWe are in search of skilled and driven legal professionals to become part of our dynamic team. We encourage you to explore our available opportunities below.OPEN POSITION ANNOUNCEMENTLead Legal Advisor or Senior Legal CounselPosition open until filled.About the Role: The Legal Department at San Diego Community Power is seeking a qualified...
-
San Diego, California, United States San Diego Unified Full timeJob SummaryThe San Diego Unified School District is seeking a highly skilled and dedicated Resource Teacher to support the STEM Department in the development and implementation of science education programs.Key Responsibilities:Develop and deliver high-quality science education programs for students in San Diego Unified School District.Collaborate with...
-
Caregiver for Seniors
3 days ago
San Diego, California, United States SENIOR HELPERS EAST SAN DIEGO Full timeAbout the RoleWe are seeking compassionate and dedicated Caregivers to join our team at Senior Helpers East San Diego. As a Caregiver, you will play a vital role in providing high-quality care and support to our senior clients in their homes.ResponsibilitiesAssist with daily activities such as meal preparation, transportation, light housekeeping, and...
